RecName: Full=Gasdermin-D; AltName: Full=Gasdermin domain-containing p - Protein

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Palmitoylation at a conserved cysteine residue facilitates gasdermin D-mediated pyroptosis and cytokine release. [Proc Natl Acad Sci U S A. 2024]
Palmitoylation at a conserved cysteine residue facilitates gasdermin D-mediated pyroptosis and cytokine release.
Liu Z, Li S, Wang C, Vidmar KJ, Bracey S, Li L, Willard B, Miyagi M, Lan T, Dickinson BC, et al. Proc Natl Acad Sci U S A. 2024 Jul 16; 121(29):e2400883121. Epub 2024 Jul 9.
GSDMD suppresses keratinocyte differentiation by inhibiting FLG expression and attenuating KCTD6-mediated HDAC1 degradation in atopic dermatitis. [PeerJ. 2024]
GSDMD suppresses keratinocyte differentiation by inhibiting FLG expression and attenuating KCTD6-mediated HDAC1 degradation in atopic dermatitis.
Zhong Y, Huang T, Li X, Luo P, Zhang B. PeerJ. 2024; 12:e16768. Epub 2024 Jan 16.
Gasdermin D triggers cardiolipin-driven mitochondrial damage and pyroptosis. [Trends Immunol. 2024]
Gasdermin D triggers cardiolipin-driven mitochondrial damage and pyroptosis.
Cai Q, Shubhra QTH. Trends Immunol. 2024 Feb; 45(2):75-77. Epub 2024 Jan 18.

RefSeq protein isoforms
See 2 reference sequence protein isoforms for the GSDMD gene.

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P57764 [Domain Mapping of Disease Mut...]
P57764
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
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reagent reviews [ExactAntigen/Labome]
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ExactAntigen/Labome

RecName: Full=Gasdermin-D; AltName: Full=Gasdermin domain-containing protein 1; ...
RecName: Full=Gasdermin-D; AltName: Full=Gasdermin domain-containing protein 1; Contains: RecName: Full=Gasdermin-D, N-terminal; Short=GSDMD-NT; Short=hGSDMD-NTD; Contains: RecName: Full=Gasdermin-D, C-terminal; Short=GSDMD-CT; Short=hGSDMD-CTD; Contains: RecName: Full=Gasdermin-D, p13; AltName: Full=Gasdermin-D, 13 kDa; Short=13 kDa GSDMD; Contains: RecName: Full=Gasdermin-D, p40
gi|13124058|sp|P57764.1|GSDMD_HUMAN

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