RecName: Full=Cathepsin K; AltName: Full=Cathepsin O; AltName: Full=Ca - Protein

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Lung macrophages utilize unique cathepsin K-dependent phagosomal machinery to degrade intracellular collagen. [Life Sci Alliance. 2023]
Lung macrophages utilize unique cathepsin K-dependent phagosomal machinery to degrade intracellular collagen.
Fabrik I, Bilkei-Gorzo O, Öberg M, Fabrikova D, Fuchs J, Sihlbom C, Göransson M, Härtlova A. Life Sci Alliance. 2023 Apr; 6(4). Epub 2023 Jan 25.
Cathepsin K regulates the tumor growth and metastasis by IL-17/CTSK/EMT axis and mediates M2 macrophage polarization in castration-resistant prostate cancer. [Cell Death Dis. 2022]
Cathepsin K regulates the tumor growth and metastasis by IL-17/CTSK/EMT axis and mediates M2 macrophage polarization in castration-resistant prostate cancer.
Wu N, Wang Y, Wang K, Zhong B, Liao Y, Liang J, Jiang N. Cell Death Dis. 2022 Sep 22; 13(9):813. Epub 2022 Sep 22.
Clinical and genetic characterization of three Russian patients with pycnodysostosis due to pathogenic variants in the CTSK gene. [Mol Genet Genomic Med. 2022]
Clinical and genetic characterization of three Russian patients with pycnodysostosis due to pathogenic variants in the CTSK gene.
Markova TV, Kenis V, Melchenko E, Guseva D, Osipova D, Galeeva N, Nagornova T, Dadali EL. Mol Genet Genomic Med. 2022 May; 10(5):e1904. Epub 2022 Mar 21.

RefSeq genomic sequence
See the genomic reference sequence for the CTSK gene (NG_011848.2).
RefSeq protein
See the reference protein sequence for cathepsin K preproprotein (NP_000387.1).

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Related structures

P43235 [Domain Mapping of Disease Mut...]
P43235
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
Evolutionary Trace of Functional Site [Evolutionary Trace of Functio...]
Evolutionary Trace of Functional Site

RecName: Full=Cathepsin K; AltName: Full=Cathepsin O; AltName: Full=Cathepsin O2...
RecName: Full=Cathepsin K; AltName: Full=Cathepsin O; AltName: Full=Cathepsin O2; AltName: Full=Cathepsin X; Flags: Precursor
gi|1168793|sp|P43235.1|CATK_HUMAN

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