CLINICAL GLOBAL IMPRESSION SCALE
(7/19/05)
00 | 00
1. SEVERITY OF ILLNESS OF DISEASE UNDER STUDY Considering your total clinical experience with this particular population, how
incapacitated has the subject been within the last week?
0 = Not assessed
1 = Normal, not at all incapacitated
2 = Borderline incapacitated
3 = Mildly incapacitated
4 = Moderately incapacitated
5 = Markedly incapacitated
6 = Severely incapacitated
7 = Among the most extremely incapacitated subjects
1 = Normal, not at all incapacitated
2 = Borderline incapacitated
3 = Mildly incapacitated
4 = Moderately incapacitated
5 = Markedly incapacitated
6 = Severely incapacitated
7 = Among the most extremely incapacitated subjects
THE NEXT TWO ITEMS MAY BE OMITTED AT THE INITIAL ASSESSMENT BY MARKING "NOT ASSESSED" FOR BOTH ITEMS
2. GLOBAL IMPROVEMENT - Rate total improvement whether or not, in your
judgment, it is due entirely to drug treatment. Compared to baseline, how much has the subject changed?
0 = Not assessed
1 = Very much improved
2 = Much improved
3 = Minimally improved
4 = No change
5 = Minimally worse
6 = Much worse
7 = Very much worse
1 = Very much improved
2 = Much improved
3 = Minimally improved
4 = No change
5 = Minimally worse
6 = Much worse
7 = Very much worse
3. EFFICACY INDEX - Rate this item on the basis of DRUG EFFECT ONLY Select the terms which best describe the degrees of therapeutic effect and side
effects and record the number in the box where the two items intersect.
- EXAMPLE: therapeutic effect is rated as "Moderate" and side effects are judged "Do not
significantly interfere with subject's functioning." Record 06 in question 3.
THERAPEUTIC EFFECT SIDE EFFECTS None Do not significantly interfere with subject's functioning Significantly interferes with subject's functioning Outweighs therapeutic effect MARKED - Vast improvement
Complete or nearly complete remission of all symptoms01 02 03 04 MODERATE - Decided improvement. Partial remission of symptoms 05 06 07 08 MINIMAL - Slight improvement which doesn't alter status of care of subject 09 10 11 12 UNCHANGED OR WORSE 13 14 15 16 NOT ASSESSED = 00