| | We aligned 2,812,455 human reads, available at http://www.ncbi.nih.gov/Traces, to build34 of the human genome, available at ftp://ftp.ncbi.nih.gov/genomes/H_sapiens/, using ssahaSNP. The settings for ssahaSNP were such that the candidate SNP base in the |
| | read was at least Phred Q=23, that its neighboring 5 bases on either side of the candidate SNP all had Phred quality values of >=15 and at least 9 of the 10 neighbors match. If the number of detected SNPs |
| | for the aligned segment of a read exceeded a rate of 15 SNPs per 1000 bases then that read alignment was ignored. If a read aligned to more than one place in the genome, then only the longest alignment with the fewest SNPs was reported. Trace data was g |
| | enerated by the Human Genome |
| | Sequencing Center, Baylor College of Medicine, through a grant from NIH. |
| | This SNP analysis was performed with permission from HGSC. |
| | The SNP reads are from a pool of 8 unrelated adult African Americans, 4 male and 4 female enrolled in Houston, TX. The pool does not have a name. The 8 samples were derived from the Baylor Polymorphism Resource which includes >500 ethnically diverse sampl |
| | es used as controls for allele frequency estimates and mutation analysis. |
| | The DNA was prepped from lymphoblastoid cell lines developed from 8 unrelated African American adults. The genomic DNA was then pooled with equal quantities from each subject and the pooled DNA used to construct the genomic libraries. The cell lines repre |
| | sent a subset of |
| | anonymous samples from healthy adults included in the Baylor Polymorphism Resource. |
| | There is a URL for reference to the Baylor Polymorphism Resource - www.cardiogene.org. |
