Name: rs2981582
Published: September 21, 2022
License: Open Access

Welcome to the Reference SNP (rs) Report

All alleles are reported in the Forward orientation. Click on the Variant Details tab for details on Genomic Placement, Gene, and Amino Acid changes. HGVS names are in the HGVS tab.

Reference SNP (rs) Report

This page reports data for a single dbSNP Reference SNP variation (RefSNP or rs) from the new redesigned dbSNP build.
Top of the page reports a concise summary for the rs, with more specific details included in the corresponding tabs below.
All alleles are reported in the Forward orientation. Use the Genomic View to inspect the nucleotides flanking the variant, and its neighbors.
For more information see Help documentation.

rs2981582

Current Build 156

Released September 21, 2022

Organism: Homo sapiens
Position: chr10:121592803 (GRCh38.p14) Help
The anchor position for this RefSNP. Includes all nucleotides potentially affected by this change, thus it can differ from HGVS, which is right-shifted. See here for details.
Alleles: A>G
Variation Type: SNV Single Nucleotide Variation
Frequency: A=0.396044 (114414/288892, ALFA)
A=0.418762 (110842/264690, TOPMED)
A=0.419230 (58636/139866, GnomAD) (+ 21 more)
A=0.40912 (32190/78682, PAGE_STUDY)
A=0.27560 (7788/28258, 14KJPN)
A=0.27822 (4663/16760, 8.3KJPN)
A=0.4052 (2595/6404, 1000G_30x)
A=0.4038 (2022/5008, 1000G)
A=0.3609 (1617/4480, Estonian)
A=0.3825 (1474/3854, ALSPAC)
A=0.3954 (1466/3708, TWINSUK)
A=0.2696 (790/2930, KOREAN)
A=0.4223 (799/1892, HapMap)
A=0.2800 (513/1832, Korea1K)
A=0.4407 (498/1130, Daghestan)
A=0.407 (406/998, GoNL)
A=0.328 (258/786, PRJEB37584)
A=0.412 (247/600, NorthernSweden)
A=0.259 (127/490, SGDP_PRJ)
A=0.375 (81/216, Qatari)
A=0.371 (78/210, Vietnamese)
G=0.45 (36/80, Ancient Sardinia)
A=0.25 (14/56, Siberian)
A=0.40 (16/40, GENOME_DK)

Clinical Significance: Reported in ClinVar
Gene : Consequence: FGFR2 : Intron Variant
Publications: 229 citations
Genomic View: See rs on genome

ALFA Allele Frequency
The ALFA project provide aggregate allele frequency from dbGaP. More information is available on the project page including descriptions, data access, and terms of use.

Release Version: 20231103111315

Population	Group	Sample Size	Ref Allele	Alt Allele
Total	Global	288986	A=0.396047	G=0.603953
European	Sub	252928	A=0.393515	G=0.606485
African	Sub	11332	A=0.48112	G=0.51888
African Others	Sub	392	A=0.551	G=0.449
African American	Sub	10940	A=0.47861	G=0.52139
Asian	Sub	3944	A=0.2898	G=0.7102
East Asian	Sub	3156	A=0.2909	G=0.7091
Other Asian	Sub	788	A=0.286	G=0.714
Latin American 1	Sub	1126	A=0.3872	G=0.6128
Latin American 2	Sub	4740	A=0.4006	G=0.5994
South Asian	Sub	380	A=0.350	G=0.650
Other	Sub	14536	A=0.40300	G=0.59700

Frequency tab displays a table of the reference and alternate allele frequencies reported by various studies and populations. Table lines, where Population="Global" refer to the entire study population, whereas lines, where Group="Sub", refer to a study-specific population subgroupings (i.e. AFR, CAU, etc.), if available. Frequency for the alternate allele (Alt Allele) is a ratio of samples observed-to-total, where the numerator (observed samples) is the number of chromosomes in the study with the minor allele present (found in "Sample size", where Group="Sub"), and the denominator (total samples) is the total number of all chromosomes in the study for the variant (found in "Sample size", where Group="Study-wide" and Population="Global").

Download

Study	Population	Group	Sample Size	Ref Allele	Alt Allele
Allele Frequency Aggregator	Total	Global	288892	A=0.396044	G=0.603956
Allele Frequency Aggregator	European	Sub	252852	A=0.393515	G=0.606485
Allele Frequency Aggregator	Other	Sub	14518	A=0.40295	G=0.59705
Allele Frequency Aggregator	African	Sub	11332	A=0.48112	G=0.51888
Allele Frequency Aggregator	Latin American 2	Sub	4740	A=0.4006	G=0.5994
Allele Frequency Aggregator	Asian	Sub	3944	A=0.2898	G=0.7102
Allele Frequency Aggregator	Latin American 1	Sub	1126	A=0.3872	G=0.6128
Allele Frequency Aggregator	South Asian	Sub	380	A=0.350	G=0.650
TopMed	Global	Study-wide	264690	A=0.418762	G=0.581238
gnomAD - Genomes	Global	Study-wide	139866	A=0.419230	G=0.580770
gnomAD - Genomes	European	Sub	75772	A=0.39219	G=0.60781
gnomAD - Genomes	African	Sub	41872	A=0.47927	G=0.52073
gnomAD - Genomes	American	Sub	13622	A=0.40611	G=0.59389
gnomAD - Genomes	Ashkenazi Jewish	Sub	3324	A=0.4233	G=0.5767
gnomAD - Genomes	East Asian	Sub	3128	A=0.3194	G=0.6806
gnomAD - Genomes	Other	Sub	2148	A=0.4250	G=0.5750
The PAGE Study	Global	Study-wide	78682	A=0.40912	G=0.59088
The PAGE Study	AfricanAmerican	Sub	32506	A=0.47065	G=0.52935
The PAGE Study	Mexican	Sub	10806	A=0.38220	G=0.61780
The PAGE Study	Asian	Sub	8318	A=0.2711	G=0.7289
The PAGE Study	PuertoRican	Sub	7916	A=0.4377	G=0.5623
The PAGE Study	NativeHawaiian	Sub	4534	A=0.2417	G=0.7583
The PAGE Study	Cuban	Sub	4230	A=0.3931	G=0.6069
The PAGE Study	Dominican	Sub	3828	A=0.4410	G=0.5590
The PAGE Study	CentralAmerican	Sub	2450	A=0.4098	G=0.5902
The PAGE Study	SouthAmerican	Sub	1980	A=0.4025	G=0.5975
The PAGE Study	NativeAmerican	Sub	1260	A=0.4008	G=0.5992
The PAGE Study	SouthAsian	Sub	854	A=0.337	G=0.663
14KJPN	JAPANESE	Study-wide	28258	A=0.27560	G=0.72440
8.3KJPN	JAPANESE	Study-wide	16760	A=0.27822	G=0.72178
1000Genomes_30x	Global	Study-wide	6404	A=0.4052	G=0.5948
1000Genomes_30x	African	Sub	1786	A=0.4933	G=0.5067
1000Genomes_30x	Europe	Sub	1266	A=0.4202	G=0.5798
1000Genomes_30x	South Asian	Sub	1202	A=0.3361	G=0.6639
1000Genomes_30x	East Asian	Sub	1170	A=0.3120	G=0.6880
1000Genomes_30x	American	Sub	980	A=0.421	G=0.579
1000Genomes	Global	Study-wide	5008	A=0.4038	G=0.5962
1000Genomes	African	Sub	1322	A=0.4947	G=0.5053
1000Genomes	East Asian	Sub	1008	A=0.3165	G=0.6835
1000Genomes	Europe	Sub	1006	A=0.4205	G=0.5795
1000Genomes	South Asian	Sub	978	A=0.344	G=0.656
1000Genomes	American	Sub	694	A=0.418	G=0.582
Genetic variation in the Estonian population	Estonian	Study-wide	4480	A=0.3609	G=0.6391
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.3825	G=0.6175
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.3954	G=0.6046
KOREAN population from KRGDB	KOREAN	Study-wide	2930	A=0.2696	G=0.7304
HapMap	Global	Study-wide	1892	A=0.4223	G=0.5777
HapMap	American	Sub	770	A=0.409	G=0.591
HapMap	African	Sub	692	A=0.499	G=0.501
HapMap	Asian	Sub	254	A=0.272	G=0.728
HapMap	Europe	Sub	176	A=0.398	G=0.602
Korean Genome Project	KOREAN	Study-wide	1832	A=0.2800	G=0.7200
Genome-wide autozygosity in Daghestan	Global	Study-wide	1130	A=0.4407	G=0.5593
Genome-wide autozygosity in Daghestan	Daghestan	Sub	626	A=0.454	G=0.546
Genome-wide autozygosity in Daghestan	Near_East	Sub	144	A=0.514	G=0.486
Genome-wide autozygosity in Daghestan	Central Asia	Sub	120	A=0.383	G=0.617
Genome-wide autozygosity in Daghestan	Europe	Sub	108	A=0.454	G=0.546
Genome-wide autozygosity in Daghestan	South Asian	Sub	98	A=0.26	G=0.74
Genome-wide autozygosity in Daghestan	Caucasus	Sub	34	A=0.59	G=0.41
Genome of the Netherlands Release 5	Genome of the Netherlands	Study-wide	998	A=0.407	G=0.593
CNV burdens in cranial meningiomas	Global	Study-wide	786	A=0.328	G=0.672
CNV burdens in cranial meningiomas	CRM	Sub	786	A=0.328	G=0.672
Northern Sweden	ACPOP	Study-wide	600	A=0.412	G=0.588
SGDP_PRJ	Global	Study-wide	490	A=0.259	G=0.741
Qatari	Global	Study-wide	216	A=0.375	G=0.625
A Vietnamese Genetic Variation Database	Global	Study-wide	210	A=0.371	G=0.629
Ancient Sardinia genome-wide 1240k capture data generation and analysis	Global	Study-wide	80	A=0.55	G=0.45
Siberian	Global	Study-wide	56	A=0.25	G=0.75
The Danish reference pan genome	Danish	Study-wide	40	A=0.40	G=0.60

Variant Details tab shows known variant placements on genomic sequences: chromosomes (NC_), RefSeqGene, pseudogenes or genomic regions (NG_), and in a separate table: on transcripts (NM_) and protein sequences (NP_). The corresponding transcript and protein locations are listed in adjacent lines, along with molecular consequences from Sequence Ontology. When no protein placement is available, only the transcript is listed. Column "Codon[Amino acid]" shows the actual base change in the format of "Reference > Alternate" allele, including the nucleotide codon change in transcripts, and the amino acid change in proteins, respectively, allowing for known ribosomal slippage sites. To view nucleotides adjacent to the variant use the Genomic View at the bottom of the page - zoom into the sequence until the nucleotides around the variant become visible.

Genomic Placements

Sequence name	Change
GRCh38.p14 chr 10	NC_000010.11:g.121592803A>G
GRCh37.p13 chr 10	NC_000010.10:g.123352317A>G
FGFR2 RefSeqGene (LRG_994)	NG_012449.2:g.10656T>C

Gene: FGFR2, fibroblast growth factor receptor 2 (minus strand)

Molecule type	Change	Amino acid[Codon]	SO Term
FGFR2 transcript variant 1	NM_000141.5:c.109+906T>C	N/A	Intron Variant
FGFR2 transcript variant 3	NM_001144913.1:c.109+906T… NM_001144913.1:c.109+906T>C	N/A	Intron Variant
FGFR2 transcript variant 4	NM_001144914.1:c.109+906T… NM_001144914.1:c.109+906T>C	N/A	Intron Variant
FGFR2 transcript variant 5	NM_001144915.2:c.109+906T… NM_001144915.2:c.109+906T>C	N/A	Intron Variant
FGFR2 transcript variant 6	NM_001144916.2:c.109+906T… NM_001144916.2:c.109+906T>C	N/A	Intron Variant
FGFR2 transcript variant 7	NM_001144917.2:c.109+906T… NM_001144917.2:c.109+906T>C	N/A	Intron Variant
FGFR2 transcript variant 8	NM_001144918.2:c.109+906T… NM_001144918.2:c.109+906T>C	N/A	Intron Variant
FGFR2 transcript variant 9	NM_001144919.2:c.109+906T… NM_001144919.2:c.109+906T>C	N/A	Intron Variant
FGFR2 transcript variant 16	NM_001320658.2:c.109+906T… NM_001320658.2:c.109+906T>C	N/A	Intron Variant
FGFR2 transcript variant 2	NM_022970.3:c.109+906T>C	N/A	Intron Variant
FGFR2 transcript variant 11	NM_023029.2:c.109+906T>C	N/A	Intron Variant
FGFR2 transcript variant 15	NM_001320654.2:c.	N/A	Genic Upstream Transcript Variant
FGFR2 transcript variant 14	NR_073009.2:n.	N/A	Intron Variant
FGFR2 transcript variant X1	XM_006717708.4:c.166+906T… XM_006717708.4:c.166+906T>C	N/A	Intron Variant
FGFR2 transcript variant X2	XM_006717710.5:c.166+906T… XM_006717710.5:c.166+906T>C	N/A	Intron Variant
FGFR2 transcript variant X3	XM_017015920.3:c.166+906T… XM_017015920.3:c.166+906T>C	N/A	Intron Variant
FGFR2 transcript variant X4	XM_017015921.3:c.166+906T… XM_017015921.3:c.166+906T>C	N/A	Intron Variant
FGFR2 transcript variant X10	XM_017015924.3:c.166+906T… XM_017015924.3:c.166+906T>C	N/A	Intron Variant
FGFR2 transcript variant X11	XM_017015925.3:c.166+906T… XM_017015925.3:c.166+906T>C	N/A	Intron Variant
FGFR2 transcript variant X6	XM_024447887.2:c.166+906T… XM_024447887.2:c.166+906T>C	N/A	Intron Variant
FGFR2 transcript variant X7	XM_024447888.2:c.166+906T… XM_024447888.2:c.166+906T>C	N/A	Intron Variant
FGFR2 transcript variant X8	XM_024447889.2:c.166+906T… XM_024447889.2:c.166+906T>C	N/A	Intron Variant
FGFR2 transcript variant X5	XM_024447890.2:c.166+906T… XM_024447890.2:c.166+906T>C	N/A	Intron Variant
FGFR2 transcript variant X9	XM_024447891.2:c.166+906T… XM_024447891.2:c.166+906T>C	N/A	Intron Variant

Clinical Significance tab shows a list of clinical significance entries from ClinVar associated with the variation, per allele. Click on the RCV accession (i.e. RCV000001615.2) or Allele ID (i.e. 12274) to access full ClinVar report.

Allele: G (allele ID: 45591 )

ClinVar Accession	Disease Names	Clinical Significance
RCV002054528.4	FGFR2 related craniosynostosis	Benign

Aliases tab displays HGVS names representing the variant placements and allele changes on genomic, transcript and protein sequences, per allele. HGVS name is an expression for reporting sequence accession and version, sequence type, position, and allele change. The column "Note" can have two values: "diff" means that there is a difference between the reference allele (variation interval) at the placement reported in HGVS name and the reference alleles reported in other HGVS names, and "rev" means that the sequence of this variation interval at the placement reported in HGVS name is in reverse orientation to the sequence(s) of this variation in other HGVS names not labeled as "rev".

Placement	A=	G
GRCh38.p14 chr 10	NC_000010.11:g.121592803=	NC_000010.11:g.121592803A>G
GRCh37.p13 chr 10	NC_000010.10:g.123352317=	NC_000010.10:g.123352317A>G
FGFR2 RefSeqGene (LRG_994)	NG_012449.2:g.10656=	NG_012449.2:g.10656T>C
FGFR2 transcript variant 1	NM_000141.4:c.109+906=	NM_000141.4:c.109+906T>C
FGFR2 transcript variant 1	NM_000141.5:c.109+906=	NM_000141.5:c.109+906T>C
FGFR2 transcript variant 3	NM_001144913.1:c.109+906=	NM_001144913.1:c.109+906T>C
FGFR2 transcript variant 4	NM_001144914.1:c.109+906=	NM_001144914.1:c.109+906T>C
FGFR2 transcript variant 5	NM_001144915.1:c.109+906=	NM_001144915.1:c.109+906T>C
FGFR2 transcript variant 5	NM_001144915.2:c.109+906=	NM_001144915.2:c.109+906T>C
FGFR2 transcript variant 6	NM_001144916.1:c.109+906=	NM_001144916.1:c.109+906T>C
FGFR2 transcript variant 6	NM_001144916.2:c.109+906=	NM_001144916.2:c.109+906T>C
FGFR2 transcript variant 7	NM_001144917.1:c.109+906=	NM_001144917.1:c.109+906T>C
FGFR2 transcript variant 7	NM_001144917.2:c.109+906=	NM_001144917.2:c.109+906T>C
FGFR2 transcript variant 8	NM_001144918.1:c.109+906=	NM_001144918.1:c.109+906T>C
FGFR2 transcript variant 8	NM_001144918.2:c.109+906=	NM_001144918.2:c.109+906T>C
FGFR2 transcript variant 9	NM_001144919.1:c.109+906=	NM_001144919.1:c.109+906T>C
FGFR2 transcript variant 9	NM_001144919.2:c.109+906=	NM_001144919.2:c.109+906T>C
FGFR2 transcript variant 16	NM_001320658.2:c.109+906=	NM_001320658.2:c.109+906T>C
FGFR2 transcript variant 2	NM_022970.3:c.109+906=	NM_022970.3:c.109+906T>C
FGFR2 transcript variant 11	NM_023029.2:c.109+906=	NM_023029.2:c.109+906T>C
FGFR2 transcript variant X1	XM_006717708.4:c.166+906=	XM_006717708.4:c.166+906T>C
FGFR2 transcript variant X2	XM_006717710.5:c.166+906=	XM_006717710.5:c.166+906T>C
FGFR2 transcript variant X3	XM_017015920.3:c.166+906=	XM_017015920.3:c.166+906T>C
FGFR2 transcript variant X4	XM_017015921.3:c.166+906=	XM_017015921.3:c.166+906T>C
FGFR2 transcript variant X10	XM_017015924.3:c.166+906=	XM_017015924.3:c.166+906T>C
FGFR2 transcript variant X11	XM_017015925.3:c.166+906=	XM_017015925.3:c.166+906T>C
FGFR2 transcript variant X6	XM_024447887.2:c.166+906=	XM_024447887.2:c.166+906T>C
FGFR2 transcript variant X7	XM_024447888.2:c.166+906=	XM_024447888.2:c.166+906T>C
FGFR2 transcript variant X8	XM_024447889.2:c.166+906=	XM_024447889.2:c.166+906T>C
FGFR2 transcript variant X5	XM_024447890.2:c.166+906=	XM_024447890.2:c.166+906T>C
FGFR2 transcript variant X9	XM_024447891.2:c.166+906=	XM_024447891.2:c.166+906T>C

Submissions tab displays variations originally submitted to dbSNP, now supporting this RefSNP cluster (rs). We display Submitter handle, Submission identifier, Date and Build number, when the submission appeared for the first time. Direct submissions to dbSNP have Submission ID in the form of an ss-prefixed number (ss#). Other supporting variations are listed in the table without ss#.

157 SubSNP, 24 Frequency, 1 ClinVar submissions

No	Submitter	Submission ID	Date (Build)
1	SC_JCM	ss4196009	Nov 05, 2001 (101)
2	COX	ss4383844	Mar 26, 2002 (103)
3	BCM_SSAHASNP	ss10590154	Jul 11, 2003 (116)
4	WI_SSAHASNP	ss12067027	Jul 11, 2003 (116)
5	CSHL-HAPMAP	ss19878615	Feb 27, 2004 (120)
6	SSAHASNP	ss20699878	Apr 05, 2004 (121)
7	PERLEGEN	ss23605537	Sep 20, 2004 (123)
8	ABI	ss38524476	Mar 15, 2006 (126)
9	PERLEGEN	ss69093877	May 18, 2007 (127)
10	STRUEWING	ss71651721	May 21, 2007 (130)
11	ILLUMINA	ss74972407	Dec 07, 2007 (129)
12	AFFY	ss76583667	Dec 07, 2007 (129)
13	KRIBB_YJKIM	ss80746050	Dec 14, 2007 (130)
14	HGSV	ss81629183	Dec 14, 2007 (130)
15	HGSV	ss81681437	Dec 14, 2007 (130)
16	HGSV	ss84217602	Dec 14, 2007 (130)
17	HUMANGENOME_JCVI	ss97690747	Feb 03, 2009 (130)
18	SNP500CANCER	ss105440200	Feb 03, 2009 (130)
19	BGI	ss106707859	Feb 03, 2009 (130)
20	1000GENOMES	ss109812842	Jan 24, 2009 (130)
21	1000GENOMES	ss113931414	Jan 25, 2009 (130)
22	KRIBB_YJKIM	ss119452166	Dec 01, 2009 (131)
23	ENSEMBL	ss131849495	Dec 01, 2009 (131)
24	GMI	ss155640126	Dec 01, 2009 (131)
25	ILLUMINA	ss160604438	Dec 01, 2009 (131)
26	COMPLETE_GENOMICS	ss168780501	Jul 04, 2010 (132)
27	COMPLETE_GENOMICS	ss171248228	Jul 04, 2010 (132)
28	ILLUMINA	ss173546621	Jul 04, 2010 (132)
29	COMPLETE_GENOMICS	ss174785842	Jul 04, 2010 (132)
30	PAGE_STUDY	ss181341901	Jul 04, 2010 (132)
31	BUSHMAN	ss202114964	Jul 04, 2010 (132)
32	BCM-HGSC-SUB	ss207374847	Jul 04, 2010 (132)
33	1000GENOMES	ss224983724	Jul 14, 2010 (132)
34	1000GENOMES	ss235363912	Jul 15, 2010 (132)
35	1000GENOMES	ss242034432	Jul 15, 2010 (132)
36	GMI	ss280803156	May 04, 2012 (137)
37	PJP	ss290948691	May 09, 2011 (134)
38	ILLUMINA	ss410927685	Sep 17, 2011 (135)
39	PAGE_STUDY	ss469414480	May 04, 2012 (137)
40	PAGE_STUDY	ss469996489	May 04, 2012 (137)
41	ILLUMINA	ss480734226	May 04, 2012 (137)
42	ILLUMINA	ss480750009	May 04, 2012 (137)
43	ILLUMINA	ss481632131	Sep 08, 2015 (146)
44	ILLUMINA	ss485161810	May 04, 2012 (137)
45	EXOME_CHIP	ss491441433	May 04, 2012 (137)
46	ILLUMINA	ss537154995	Sep 08, 2015 (146)
47	TISHKOFF	ss562260226	Apr 25, 2013 (138)
48	SSMP	ss657492375	Apr 25, 2013 (138)
49	ILLUMINA	ss778513881	Sep 08, 2015 (146)
50	ILLUMINA	ss780684129	Sep 08, 2015 (146)
51	ILLUMINA	ss783027161	Sep 08, 2015 (146)
52	ILLUMINA	ss783357559	Sep 08, 2015 (146)
53	ILLUMINA	ss783986964	Sep 08, 2015 (146)
54	CLINVAR	ss831878788	Nov 05, 2013 (136)
55	ILLUMINA	ss832284748	Sep 08, 2015 (146)
56	ILLUMINA	ss833970180	Sep 08, 2015 (146)
57	EVA-GONL	ss988003899	Aug 21, 2014 (142)
58	JMKIDD_LAB	ss1077358634	Aug 21, 2014 (142)
59	1000GENOMES	ss1339378413	Aug 21, 2014 (142)
60	HAMMER_LAB	ss1397594591	Sep 08, 2015 (146)
61	DDI	ss1426467758	Apr 01, 2015 (144)
62	EVA_GENOME_DK	ss1575402325	Apr 01, 2015 (144)
63	EVA_DECODE	ss1597683038	Apr 01, 2015 (144)
64	EVA_UK10K_ALSPAC	ss1625605694	Apr 01, 2015 (144)
65	EVA_UK10K_TWINSUK	ss1668599727	Apr 01, 2015 (144)
66	EVA_SVP	ss1713217801	Apr 01, 2015 (144)
67	ILLUMINA	ss1751951486	Sep 08, 2015 (146)
68	ILLUMINA	ss1751951487	Sep 08, 2015 (146)
69	HAMMER_LAB	ss1806604686	Sep 08, 2015 (146)
70	ILLUMINA	ss1917852390	Feb 12, 2016 (147)
71	WEILL_CORNELL_DGM	ss1931361777	Feb 12, 2016 (147)
72	ILLUMINA	ss1946295211	Feb 12, 2016 (147)
73	ILLUMINA	ss1959301178	Feb 12, 2016 (147)
74	GENOMED	ss1967243413	Jul 19, 2016 (147)
75	JJLAB	ss2026417697	Sep 14, 2016 (149)
76	ILLUMINA	ss2094789373	Dec 20, 2016 (150)
77	ILLUMINA	ss2095017822	Dec 20, 2016 (150)
78	USC_VALOUEV	ss2154694917	Dec 20, 2016 (150)
79	HUMAN_LONGEVITY	ss2178726637	Dec 20, 2016 (150)
80	SYSTEMSBIOZJU	ss2627675782	Nov 08, 2017 (151)
81	ILLUMINA	ss2632772623	Nov 08, 2017 (151)
82	ILLUMINA	ss2632772624	Nov 08, 2017 (151)
83	ILLUMINA	ss2635020002	Nov 08, 2017 (151)
84	ILLUMINA	ss2635020003	Nov 08, 2017 (151)
85	GRF	ss2698956109	Nov 08, 2017 (151)
86	ILLUMINA	ss2710722945	Nov 08, 2017 (151)
87	GNOMAD	ss2894272913	Nov 08, 2017 (151)
88	AFFY	ss2984925575	Nov 08, 2017 (151)
89	AFFY	ss2985573693	Nov 08, 2017 (151)
90	SWEGEN	ss3007274302	Nov 08, 2017 (151)
91	ILLUMINA	ss3021282738	Nov 08, 2017 (151)
92	BIOINF_KMB_FNS_UNIBA	ss3026997949	Nov 08, 2017 (151)
93	CSHL	ss3349347416	Nov 08, 2017 (151)
94	ILLUMINA	ss3626552452	Oct 12, 2018 (152)
95	ILLUMINA	ss3626552453	Oct 12, 2018 (152)
96	ILLUMINA	ss3630794291	Oct 12, 2018 (152)
97	ILLUMINA	ss3632967750	Oct 12, 2018 (152)
98	ILLUMINA	ss3633665696	Oct 12, 2018 (152)
99	ILLUMINA	ss3634428033	Oct 12, 2018 (152)
100	ILLUMINA	ss3634428034	Oct 12, 2018 (152)
101	ILLUMINA	ss3635357784	Oct 12, 2018 (152)
102	ILLUMINA	ss3636112809	Oct 12, 2018 (152)
103	ILLUMINA	ss3637108538	Oct 12, 2018 (152)
104	ILLUMINA	ss3637878746	Oct 12, 2018 (152)
105	ILLUMINA	ss3640135374	Oct 12, 2018 (152)
106	ILLUMINA	ss3640135375	Oct 12, 2018 (152)
107	ILLUMINA	ss3641007803	Oct 12, 2018 (152)
108	ILLUMINA	ss3641302159	Oct 12, 2018 (152)
109	ILLUMINA	ss3642879572	Oct 12, 2018 (152)
110	ILLUMINA	ss3644547981	Oct 12, 2018 (152)
111	URBANLAB	ss3649484749	Oct 12, 2018 (152)
112	ILLUMINA	ss3651642390	Oct 12, 2018 (152)
113	ILLUMINA	ss3651642391	Oct 12, 2018 (152)
114	ILLUMINA	ss3653696835	Oct 12, 2018 (152)
115	EGCUT_WGS	ss3674693315	Jul 13, 2019 (153)
116	EVA_DECODE	ss3690836827	Jul 13, 2019 (153)
117	ILLUMINA	ss3725195676	Jul 13, 2019 (153)
118	ACPOP	ss3737747337	Jul 13, 2019 (153)
119	ILLUMINA	ss3744372754	Jul 13, 2019 (153)
120	ILLUMINA	ss3744729000	Jul 13, 2019 (153)
121	ILLUMINA	ss3744729001	Jul 13, 2019 (153)
122	EVA	ss3748702163	Jul 13, 2019 (153)
123	PAGE_CC	ss3771588546	Jul 13, 2019 (153)
124	ILLUMINA	ss3772229232	Jul 13, 2019 (153)
125	ILLUMINA	ss3772229233	Jul 13, 2019 (153)
126	PACBIO	ss3786809588	Jul 13, 2019 (153)
127	PACBIO	ss3791968613	Jul 13, 2019 (153)
128	PACBIO	ss3796850754	Jul 13, 2019 (153)
129	KHV_HUMAN_GENOMES	ss3814059434	Jul 13, 2019 (153)
130	EVA	ss3832372541	Apr 26, 2020 (154)
131	EVA	ss3839727673	Apr 26, 2020 (154)
132	EVA	ss3845202456	Apr 26, 2020 (154)
133	SGDP_PRJ	ss3875220396	Apr 26, 2020 (154)
134	KRGDB	ss3923399818	Apr 26, 2020 (154)
135	KOGIC	ss3968829535	Apr 26, 2020 (154)
136	EVA	ss3984642209	Apr 26, 2021 (155)
137	EVA	ss3985505515	Apr 26, 2021 (155)
138	EVA	ss4017512275	Apr 26, 2021 (155)
139	TOPMED	ss4869198206	Apr 26, 2021 (155)
140	TOMMO_GENOMICS	ss5199827882	Apr 26, 2021 (155)
141	1000G_HIGH_COVERAGE	ss5285742554	Oct 16, 2022 (156)
142	EVA	ss5315508837	Oct 16, 2022 (156)
143	EVA	ss5396545637	Oct 16, 2022 (156)
144	HUGCELL_USP	ss5481137875	Oct 16, 2022 (156)
145	1000G_HIGH_COVERAGE	ss5580559704	Oct 16, 2022 (156)
146	SANFORD_IMAGENETICS	ss5624260940	Oct 16, 2022 (156)
147	SANFORD_IMAGENETICS	ss5650254514	Oct 16, 2022 (156)
148	TOMMO_GENOMICS	ss5746300922	Oct 16, 2022 (156)
149	EVA	ss5799827535	Oct 16, 2022 (156)
150	YY_MCH	ss5811952461	Oct 16, 2022 (156)
151	EVA	ss5825066767	Oct 16, 2022 (156)
152	EVA	ss5847381557	Oct 16, 2022 (156)
153	EVA	ss5847612794	Oct 16, 2022 (156)
154	EVA	ss5849775095	Oct 16, 2022 (156)
155	EVA	ss5880848713	Oct 16, 2022 (156)
156	EVA	ss5941561313	Oct 16, 2022 (156)
157	EVA	ss5979341577	Oct 16, 2022 (156)
158	1000Genomes	NC_000010.10 - 123352317	Oct 12, 2018 (152)
159	1000Genomes_30x	NC_000010.11 - 121592803	Oct 16, 2022 (156)
160	The Avon Longitudinal Study of Parents and Children	NC_000010.10 - 123352317	Oct 12, 2018 (152)
161	Genome-wide autozygosity in Daghestan	NC_000010.9 - 123342307	Apr 26, 2020 (154)
162	Genetic variation in the Estonian population	NC_000010.10 - 123352317	Oct 12, 2018 (152)
163	The Danish reference pan genome	NC_000010.10 - 123352317	Apr 26, 2020 (154)
164	gnomAD - Genomes	NC_000010.11 - 121592803	Apr 26, 2021 (155)
165	Genome of the Netherlands Release 5	NC_000010.10 - 123352317	Apr 26, 2020 (154)
166	HapMap	NC_000010.11 - 121592803	Apr 26, 2020 (154)
167	KOREAN population from KRGDB	NC_000010.10 - 123352317	Apr 26, 2020 (154)
168	Korean Genome Project	NC_000010.11 - 121592803	Apr 26, 2020 (154)
169	Northern Sweden	NC_000010.10 - 123352317	Jul 13, 2019 (153)
170	The PAGE Study	NC_000010.11 - 121592803	Jul 13, 2019 (153)
171	Ancient Sardinia genome-wide 1240k capture data generation and analysis	NC_000010.10 - 123352317	Apr 26, 2021 (155)
172	CNV burdens in cranial meningiomas	NC_000010.10 - 123352317	Apr 26, 2021 (155)
173	Qatari	NC_000010.10 - 123352317	Apr 26, 2020 (154)
174	SGDP_PRJ	NC_000010.10 - 123352317	Apr 26, 2020 (154)
175	Siberian	NC_000010.10 - 123352317	Apr 26, 2020 (154)
176	8.3KJPN	NC_000010.10 - 123352317	Apr 26, 2021 (155)
177	14KJPN	NC_000010.11 - 121592803	Oct 16, 2022 (156)
178	TopMed	NC_000010.11 - 121592803	Apr 26, 2021 (155)
179	UK 10K study - Twins	NC_000010.10 - 123352317	Oct 12, 2018 (152)
180	A Vietnamese Genetic Variation Database	NC_000010.10 - 123352317	Jul 13, 2019 (153)
181	ALFA	NC_000010.11 - 121592803	Apr 26, 2021 (155)
182	ClinVar	RCV002054528.4	Oct 16, 2022 (156)

History tab displays RefSNPs (Associated ID) from previous builds (Build) that now support the current RefSNP, and the dates, when the history was updated for each Associated ID (History Updated).

Associated ID	History Updated (Build)
rs45631640	May 23, 2008 (130)
rs56718061	May 23, 2008 (130)

Added to this RefSNP Cluster:

Submission IDs	Observation SPDI	Canonical SPDI	Source RSIDs
ss81629183, ss81681437, ss84217602	NC_000010.8:123342306:A:G	NC_000010.11:121592802:A:G	(self)
65951, ss76583667, ss109812842, ss113931414, ss168780501, ss171248228, ss174785842, ss202114964, ss207374847, ss280803156, ss290948691, ss480734226, ss1397594591, ss1597683038, ss1713217801, ss2635020002, ss2635020003, ss3642879572	NC_000010.9:123342306:A:G	NC_000010.11:121592802:A:G	(self)
51836866, 28796322, 20431563, 2359111, 12833607, 30577212, 11032202, 731442, 191679, 13403707, 27237376, 7211271, 57797189, 28796322, 6389751, ss224983724, ss235363912, ss242034432, ss480750009, ss481632131, ss485161810, ss491441433, ss537154995, ss562260226, ss657492375, ss778513881, ss780684129, ss783027161, ss783357559, ss783986964, ss832284748, ss833970180, ss988003899, ss1077358634, ss1339378413, ss1426467758, ss1575402325, ss1625605694, ss1668599727, ss1751951486, ss1751951487, ss1806604686, ss1917852390, ss1931361777, ss1946295211, ss1959301178, ss1967243413, ss2026417697, ss2094789373, ss2095017822, ss2154694917, ss2627675782, ss2632772623, ss2632772624, ss2698956109, ss2710722945, ss2894272913, ss2984925575, ss2985573693, ss3007274302, ss3021282738, ss3349347416, ss3626552452, ss3626552453, ss3630794291, ss3632967750, ss3633665696, ss3634428033, ss3634428034, ss3635357784, ss3636112809, ss3637108538, ss3637878746, ss3640135374, ss3640135375, ss3641007803, ss3641302159, ss3644547981, ss3651642390, ss3651642391, ss3653696835, ss3674693315, ss3737747337, ss3744372754, ss3744729000, ss3744729001, ss3748702163, ss3772229232, ss3772229233, ss3786809588, ss3791968613, ss3796850754, ss3832372541, ss3839727673, ss3875220396, ss3923399818, ss3984642209, ss3985505515, ss4017512275, ss5199827882, ss5315508837, ss5396545637, ss5624260940, ss5650254514, ss5799827535, ss5825066767, ss5847381557, ss5847612794, ss5941561313, ss5979341577	NC_000010.10:123352316:A:G	NC_000010.11:121592802:A:G	(self)
RCV002054528.4, 68085639, 366226563, 510256, 25207536, 810015, 80138026, 84743861, 12789307823, ss831878788, ss2178726637, ss3026997949, ss3649484749, ss3690836827, ss3725195676, ss3771588546, ss3814059434, ss3845202456, ss3968829535, ss4869198206, ss5285742554, ss5481137875, ss5580559704, ss5746300922, ss5811952461, ss5849775095, ss5880848713	NC_000010.11:121592802:A:G	NC_000010.11:121592802:A:G	(self)
ss10590154, ss12067027	NT_030059.10:41790874:A:G	NC_000010.11:121592802:A:G	(self)
ss19878615, ss20699878	NT_030059.11:42100842:A:G	NC_000010.11:121592802:A:G	(self)
ss4196009, ss4383844, ss23605537, ss38524476, ss69093877, ss71651721, ss74972407, ss80746050, ss97690747, ss105440200, ss106707859, ss119452166, ss131849495, ss155640126, ss160604438, ss173546621, ss181341901, ss410927685, ss469414480, ss469996489	NT_030059.13:74156780:A:G	NC_000010.11:121592802:A:G	(self)

Publications tab displays PubMed articles citing the variation as a listing of PMID, Title, Author, Year, Journal, ordered by Year, descending.

229 citations for rs2981582

PMID	Title	Author	Year	Journal
17529967	Genome-wide association study identifies novel breast cancer susceptibility loci.	Easton DF et al.	2007	Nature
17529973	A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer.	Hunter DJ et al.	2007	Nature genetics
17997823	Clinical correlates of low-risk variants in FGFR2, TNRC9, MAP3K1, LSP1 and 8q24 in a Dutch cohort of incident breast cancer cases.	Huijts PE et al.	2007	Breast cancer research
18224312	Pharmacogenetics: data, concepts and tools to improve drug discovery and drug treatment.	Brockmöller J et al.	2008	European journal of clinical pharmacology
18285324	Common variation in the fibroblast growth factor receptor 2 gene is not associated with endometriosis risk.	Zhao ZZ et al.	2008	Human reproduction (Oxford, England)
18326623	Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33.	Gold B et al.	2008	Proceedings of the National Academy of Sciences of the United States of America
18355772	Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers.	Antoniou AC et al.	2008	American journal of human genetics
18437204	Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics.	Garcia-Closas M et al.	2008	PLoS genetics
18462018	Allele-specific up-regulation of FGFR2 increases susceptibility to breast cancer.	Meyer KB et al.	2008	PLoS biology
18478591	Studies of genes in the FGF signaling pathway and oral clefts with or without dental anomalies.	Menezes R et al.	2008	American journal of medical genetics. Part A
18483326	FGFR2 is a breast cancer susceptibility gene in Jewish and Arab Israeli populations.	Raskin L et al.	2008	Cancer epidemiology, biomarkers & prevention
18535005	The search for genes contributing to endometriosis risk.	Montgomery GW et al.	2008	Human reproduction update
18612136	Discriminatory accuracy from single-nucleotide polymorphisms in models to predict breast cancer risk.	Gail MH et al.	2008	Journal of the National Cancer Institute
18681954	Breast cancer susceptibility loci and mammographic density.	Tamimi RM et al.	2008	Breast cancer research
18708391	Breast cancer risk polymorphisms and interaction with ionizing radiation among U.S. radiologic technologists.	Bhatti P et al.	2008	Cancer epidemiology, biomarkers & prevention
18772892	Can genes for mammographic density inform cancer aetiology?	Kelemen LE et al.	2008	Nature reviews. Cancer
18785201	Novel breast cancer risk alleles and endometrial cancer risk.	McGrath M et al.	2008	International journal of cancer
18845558	Genetic variants in fibroblast growth factor receptor 2 (FGFR2) contribute to susceptibility of breast cancer in Chinese women.	Liang J et al.	2008	Carcinogenesis
18973230	Breast cancer susceptibility alleles and ovarian cancer risk in 2 study populations.	Gates MA et al.	2009	International journal of cancer
19005751	Low penetrance breast cancer predisposition SNPs are site specific.	Mcinerney N et al.	2009	Breast cancer research and treatment
19028704	Hormone-dependent effects of FGFR2 and MAP3K1 in breast cancer susceptibility in a population-based sample of post-menopausal African-American and European-American women.	Rebbeck TR et al.	2009	Carcinogenesis
19088016	Genetic susceptibility loci for breast cancer by estrogen receptor status.	Garcia-Closas M et al.	2008	Clinical cancer research
19092773	Breast cancer susceptibility: current knowledge and implications for genetic counselling.	Ripperger T et al.	2009	European journal of human genetics
19094228	The influence of genetic variation in 30 selected genes on the clinical characteristics of early onset breast cancer.	Tapper W et al.	2008	Breast cancer research
19119171	AXIS inhibition protein 2, orofacial clefts and a family history of cancer.	Menezes R et al.	2009	Journal of the American Dental Association (1939)
19219042	Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1.	Zheng W et al.	2009	Nature genetics
19223389	FGFR2 variants and breast cancer risk: fine-scale mapping using African American studies and analysis of chromatin conformation.	Udler MS et al.	2009	Human molecular genetics
19232126	Association between breast cancer susceptibility loci and mammographic density: the Multiethnic Cohort.	Woolcott CG et al.	2009	Breast cancer research
19304784	Association between invasive ovarian cancer susceptibility and 11 best candidate SNPs from breast cancer genome-wide association study.	Song H et al.	2009	Human molecular genetics
19454617	Genetic variation in the chromosome 17q23 amplicon and breast cancer risk.	Kelemen LE et al.	2009	Cancer epidemiology, biomarkers & prevention
19497954	Histone-acetylated control of fibroblast growth factor receptor 2 intron 2 polymorphisms and isoform splicing in breast cancer.	Zhu X et al.	2009	Molecular endocrinology (Baltimore, Md.)
19519208	Polygenic susceptibility to breast cancer: current state-of-the-art.	Ghoussaini M et al.	2009	Future oncology (London, England)
19536173	Association of FGFR2 gene polymorphisms with the risk of breast cancer in population of West Siberia.	Boyarskikh UA et al.	2009	European journal of human genetics
19567422	Risk of estrogen receptor-positive and -negative breast cancer and single-nucleotide polymorphism 2q35-rs13387042.	Milne RL et al.	2009	Journal of the National Cancer Institute
19607694	Low-risk susceptibility alleles in 40 human breast cancer cell lines.	Riaz M et al.	2009	BMC cancer
19639606	Correcting "winner's curse" in odds ratios from genomewide association findings for major complex human diseases.	Zhong H et al.	2010	Genetic epidemiology
19738052	A risk variant in an miR-125b binding site in BMPR1B is associated with breast cancer pathogenesis.	Saetrom P et al.	2009	Cancer research
19789366	Evaluation of 11 breast cancer susceptibility loci in African-American women.	Zheng W et al.	2009	Cancer epidemiology, biomarkers & prevention
19861516	Variation in the FGFR2 gene and the effects of postmenopausal hormone therapy on invasive breast cancer.	Prentice RL et al.	2009	Cancer epidemiology, biomarkers & prevention
19931039	Using lifetime risk estimates in personal genomic profiles: estimation of uncertainty.	Yang Q et al.	2009	American journal of human genetics
20054709	Birth weight, breast cancer susceptibility loci, and breast cancer risk.	Tamimi RM et al.	2010	Cancer causes & control
20056625	Variation in the FGFR2 gene and the effect of a low-fat dietary pattern on invasive breast cancer.	Prentice RL et al.	2010	Cancer epidemiology, biomarkers & prevention
20056641	Multiple genetic variants in telomere pathway genes and breast cancer risk.	Shen J et al.	2010	Cancer epidemiology, biomarkers & prevention
20085711	Leveraging genetic variability across populations for the identification of causal variants.	Zaitlen N et al.	2010	American journal of human genetics
20126254	Rare variants create synthetic genome-wide associations.	Dickson SP et al.	2010	PLoS biology
20146796	Familial relative risks for breast cancer by pathological subtype: a population-based cohort study.	Mavaddat N et al.	2010	Breast cancer research
20193855	rs2981582 is associated with FGFR2 expression in normal breast.	Sun C et al.	2010	Cancer genetics and cytogenetics
20237344	Performance of common genetic variants in breast-cancer risk models.	Wacholder S et al.	2010	The New England journal of medicine
20299982	Evaluating cancer epidemiologic risk factors using multiple primary malignancies.	Kuligina E et al.	2010	Epidemiology (Cambridge, Mass.)
20300826	Current evidence on the relationship between three polymorphisms in the FGFR2 gene and breast cancer risk: a meta-analysis.	Zhang J et al.	2010	Breast cancer research and treatment
20348248	Genetic and epigenetic mechanisms down-regulate FGF receptor 2 to induce melanoma-associated antigen A in breast cancer.	Zhu X et al.	2010	The American journal of pathology
20364400	Quantitative assessment of the effect of FGFR2 gene polymorphism on the risk of breast cancer.	Jia C et al.	2010	Breast cancer research and treatment
20453838	Genome-wide association study identifies five new breast cancer susceptibility loci.	Turnbull C et al.	2010	Nature genetics
20484103	Genetic and clinical predictors for breast cancer risk assessment and stratification among Chinese women.	Zheng W et al.	2010	Journal of the National Cancer Institute
20505153	A compendium of genome-wide associations for cancer: critical synopsis and reappraisal.	Ioannidis JP et al.	2010	Journal of the National Cancer Institute
20530438	Unique SNP in CD44 intron 1 and its role in breast cancer development.	Zhou J et al.	2010	Anticancer research
20554749	FGFR2 and other loci identified in genome-wide association studies are associated with breast cancer in African-American and younger women.	Barnholtz-Sloan JS et al.	2010	Carcinogenesis
20585100	Genome-wide association studies of cancer.	Stadler ZK et al.	2010	Journal of clinical oncology
20605201	Gene-environment interactions in 7610 women with breast cancer: prospective evidence from the Million Women Study.	Travis RC et al.	2010	Lancet (London, England)
20664043	Incidence of breast cancer and its subtypes in relation to individual and multiple low-penetrance genetic susceptibility loci.	Reeves GK et al.	2010	JAMA
20677155	[Association of FGFR2 gene polymorphism with estrogen receptor positive breast cancer detected by fluorescent quantitative PCR].	Ren L et al.	2010	Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics
20699374	Evaluation of breast cancer susceptibility loci in Chinese women.	Long J et al.	2010	Cancer epidemiology, biomarkers & prevention
20718042	Pooled versus individual genotyping in a breast cancer genome-wide association study.	Huang Y et al.	2010	Genetic epidemiology
20853316	FGFR2 intronic SNPs and breast cancer risk: associations with tumor characteristics and interactions with exogenous exposures and other known breast cancer risk factors.	Marian C et al.	2011	International journal of cancer
20956782	Assessment of clinical validity of a breast cancer risk model combining genetic and clinical information.	Mealiffe ME et al.	2010	Journal of the National Cancer Institute
20957429	Discriminatory accuracy and potential clinical utility of genomic profiling for breast cancer risk in BRCA-negative women.	Comen E et al.	2011	Breast cancer research and treatment
20959865	Genome-wide association of breast cancer: composite likelihood with imputed genotypes.	Politopoulos I et al.	2011	European journal of human genetics
21037853	Breast cancer in the personal genomics era.	Ellsworth RE et al.	2010	Current genomics
21049069	Identification of Novel Susceptibility Genes for Breast Cancer - Genome-Wide Association Studies or Evaluation of Candidate Genes?	Meindl A et al.	2009	Breast care (Basel, Switzerland)
21060860	Common genetic variants and modification of penetrance of BRCA2-associated breast cancer.	Gaudet MM et al.	2010	PLoS genetics
21102626	Caution in generalizing known genetic risk markers for breast cancer across all ethnic/racial populations.	Chen F et al.	2011	European journal of human genetics
21118973	Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk prediction.	Antoniou AC et al.	2010	Cancer research
21132113	Direct-to-Consumer Genetic and Genomic Testing: Preparing Nurse Practitioners for Genomic Healthcare.	Loud JT et al.	2010	The journal for nurse practitioners
21194473	Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study.	Milne RL et al.	2010	Breast cancer research
21203894	Cancer susceptibility variants and the risk of adult glioma in a US case-control study.	Egan KM et al.	2011	Journal of neuro-oncology
21382839	Relation of FGFR2 genetic polymorphisms to the association between oral contraceptive use and the risk of breast cancer in Chinese women.	Xu WH et al.	2011	American journal of epidemiology
21415360	Common genetic variants associated with breast cancer in Korean women and differential susceptibility according to intrinsic subtype.	Han W et al.	2011	Cancer epidemiology, biomarkers & prevention
21418638	FGFR2 protein expression in breast cancer: nuclear localisation and correlation with patient genotype.	Martin AJ et al.	2011	BMC research notes
21445572	Genetic polymorphisms and breast cancer risk: evidence from meta-analyses, pooled analyses, and genome-wide association studies.	Peng S et al.	2011	Breast cancer research and treatment
21468051	Polygenic susceptibility to prostate and breast cancer: implications for personalised screening.	Pashayan N et al.	2011	British journal of cancer
21475998	Replication of five GWAS-identified loci and breast cancer risk among Hispanic and non-Hispanic white women living in the Southwestern United States.	Slattery ML et al.	2011	Breast cancer research and treatment
21497291	Evaluation of nanofluidics technology for high-throughput SNP genotyping in a clinical setting.	Chan M et al.	2011	The Journal of molecular diagnostics
21514219	Genetic variants associated with breast-cancer risk: comprehensive research synopsis, meta-analysis, and epidemiological evidence.	Zhang B et al.	2011	The Lancet. Oncology
21596841	Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium.	Broeks A et al.	2011	Human molecular genetics
21639959	Annual conference on hereditary cancers 2009 szczecin, poland. 10-11 december 2009. Abstracts.	Jakubowska A et al.	2011	Hereditary cancer in clinical practice
21655367	In search of breast cancer culprits: suspecting the suspected and the unsuspected.	Dimri GP et al.	2008	Breast cancer
21702935	Genetic variants in the MRPS30 region and postmenopausal breast cancer risk.	Huang Y et al.	2011	Genome medicine
21748294	Correlation of breast cancer susceptibility loci with patient characteristics, metastasis-free survival, and mRNA expression of the nearest genes.	Riaz M et al.	2012	Breast cancer research and treatment
21767389	Allele-specific regulation of FGFR2 expression is cell type-dependent and may increase breast cancer risk through a paracrine stimulus involving FGF10.	Huijts PE et al.	2011	Breast cancer research
21791674	Interactions between genetic variants and breast cancer risk factors in the breast and prostate cancer cohort consortium.	Campa D et al.	2011	Journal of the National Cancer Institute
21795498	Confirmation of 5p12 as a susceptibility locus for progesterone-receptor-positive, lower grade breast cancer.	Milne RL et al.	2011	Cancer epidemiology, biomarkers & prevention
21795501	Replication of breast cancer GWAS susceptibility loci in the Women's Health Initiative African American SHARe Study.	Hutter CM et al.	2011	Cancer epidemiology, biomarkers & prevention
21822685	Genetic variants of fibroblast growth factor receptor 2 (FGFR2) are associated with breast cancer risk in Chinese women of the Han nationality.	Chen F et al.	2012	Immunogenetics
21844186	Common breast cancer susceptibility loci are associated with triple-negative breast cancer.	Stevens KN et al.	2011	Cancer research
21852243	Fine-mapping of breast cancer susceptibility loci characterizes genetic risk in African Americans.	Chen F et al.	2011	Human molecular genetics
21869864	An integrative genomics approach to biomarker discovery in breast cancer.	Hicks C et al.	2011	Cancer informatics
21965274	Breast cancer susceptibility polymorphisms and endometrial cancer risk: a Collaborative Endometrial Cancer Study.	Healey CS et al.	2011	Carcinogenesis
22028405	Estimating causal effects of genetic risk variants for breast cancer using marker data from bilateral and familial cases.	Dudbridge F et al.	2012	Cancer epidemiology, biomarkers & prevention
22045194	Combined effect of low-penetrant SNPs on breast cancer risk.	Harlid S et al.	2012	British journal of cancer
22053997	Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2.	Mulligan AM et al.	2011	Breast cancer research
22087758	Single nucleotide polymorphisms associated with risk for contralateral breast cancer in the Women's Environment, Cancer, and Radiation Epidemiology (WECARE) Study.	Teraoka SN et al.	2011	Breast cancer research
22269215	Breast cancer risk assessment with five independent genetic variants and two risk factors in Chinese women.	Dai J et al.	2012	Breast cancer research
22303333	Replication of GWAS "Hits" by Race for Breast and Prostate Cancers in European Americans and African Americans.	Barnholtz-Sloan JS et al.	2011	Frontiers in genetics
22314178	Breast cancer risk prediction and individualised screening based on common genetic variation and breast density measurement.	Darabi H et al.	2012	Breast cancer research
22332084	Research advances at the Institute for Nutritional Sciences at Shanghai, China.	Chen Y et al.	2011	Advances in nutrition (Bethesda, Md.)
22357627	Evaluation of 19 susceptibility loci of breast cancer in women of African ancestry.	Huo D et al.	2012	Carcinogenesis
22433456	Reproductive aging-associated common genetic variants and the risk of breast cancer.	He C et al.	2012	Breast cancer research
22452962	A genome-wide association study identifies a breast cancer risk variant in ERBB4 at 2q34: results from the Seoul Breast Cancer Study.	Kim HC et al.	2012	Breast cancer research
22454379	Common breast cancer susceptibility variants in LSP1 and RAD51L1 are associated with mammographic density measures that predict breast cancer risk.	Vachon CM et al.	2012	Cancer epidemiology, biomarkers & prevention
22532573	The role of genetic breast cancer susceptibility variants as prognostic factors.	Fasching PA et al.	2012	Human molecular genetics
22726230	Interactive effect of genetic susceptibility with height, body mass index, and hormone replacement therapy on the risk of breast cancer.	Harlid S et al.	2012	BMC women's health
22747683	Genetic variants associated with breast size also influence breast cancer risk.	Eriksson N et al.	2012	BMC medical genetics
22778704	The association between single-nucleotide polymorphisms of ORAI1 gene and breast cancer in a Taiwanese population.	Chang WC et al.	2012	TheScientificWorldJournal
22867275	Genetic predisposition, parity, age at first childbirth and risk for breast cancer.	Butt S et al.	2012	BMC research notes
22910930	Genome-Wide Association Studies (GWAS) breast cancer susceptibility loci in Arabs: susceptibility and prognostic implications in Tunisians.	Shan J et al.	2012	Breast cancer research and treatment
22926736	Low penetrance alleles as risk modifiers in familial and sporadic breast cancer.	Esteban Cardeñosa E et al.	2012	Familial cancer
22965832	Association of common genetic variants with breast cancer risk and clinicopathological characteristics in a Chinese population.	Chan M et al.	2012	Breast cancer research and treatment
22972951	Prediction of breast cancer risk by genetic risk factors, overall and by hormone receptor status.	Hüsing A et al.	2012	Journal of medical genetics
23107584	Identifying breast cancer risk loci by global differential allele-specific expression (DASE) analysis in mammary epithelial transcriptome.	Gao C et al.	2012	BMC genomics
23136140	Genetic susceptibility loci for subtypes of breast cancer in an African American population.	Palmer JR et al.	2013	Cancer epidemiology, biomarkers & prevention
23143756	Associations of polymorphisms in the genes of FGFR2, FGF1, and RBFOX2 with breast cancer risk by estrogen/progesterone receptor status.	Cen YL et al.	2013	Molecular carcinogenesis
23184080	Assessing interactions between the associations of fibroblast growth factor receptor 2 common genetic variants and hormone receptor status with breast cancer risk.	Wang H et al.	2013	Breast cancer research and treatment
23221726	Gene-environment interactions for breast cancer risk among Chinese women: a report from the Shanghai Breast Cancer Genetics Study.	Li H et al.	2013	American journal of epidemiology
23225170	Genetic variants in FGFR2 and MAP3K1 are associated with the risk of familial and early-onset breast cancer in a South-American population.	Jara L et al.	2013	Breast cancer research and treatment
23354978	Genetic variants associated with breast cancer risk for Ashkenazi Jewish women with strong family histories but no identifiable BRCA1/2 mutation.	Rinella ES et al.	2013	Human genetics
23435034	Breast cancer susceptibility associated with rs1219648 (fibroblast growth factor receptor 2) and postmenopausal hormone therapy use in a population-based United States study.	Andersen SW et al.	2013	Menopause (New York, N.Y.)
23462807	Single-nucleotide polymorphisms associated with outcome in metastatic renal cell carcinoma treated with sunitinib.	Beuselinck B et al.	2013	British journal of cancer
23486537	Comparison of genetic variation of breast cancer susceptibility genes in Chinese and German populations.	Barzan D et al.	2013	European journal of human genetics
23535825	Common genetic determinants of breast-cancer risk in East Asian women: a collaborative study of 23 637 breast cancer cases and 25 579 controls.	Zheng W et al.	2013	Human molecular genetics
23544014	Evidence of gene-environment interactions between common breast cancer susceptibility loci and established environmental risk factors.	Nickels S et al.	2013	PLoS genetics
23593120	Evaluating genome-wide association study-identified breast cancer risk variants in African-American women.	Long J et al.	2013	PloS one
23635555	The relationship between eight GWAS-identified single-nucleotide polymorphisms and primary breast cancer outcomes.	Bayraktar S et al.	2013	The oncologist
23650637	Deconvoluting complex tissues for expression quantitative trait locus-based analyses.	Seo JH et al.	2013	Philosophical transactions of the Royal Society of London. Series B, Biological sciences
23717390	Identification of a breast cancer susceptibility locus at 4q31.22 using a genome-wide association study paradigm.	Sapkota Y et al.	2013	PloS one
23776363	The genetics of breast cancer: risk factors for disease.	Collins A et al.	2011	The application of clinical genetics
23893088	The associations between a polygenic score, reproductive and menstrual risk factors and breast cancer risk.	Warren Andersen S et al.	2013	Breast cancer research and treatment
23912956	Associations with growth factor genes (FGF1, FGF2, PDGFB, FGFR2, NRG2, EGF, ERBB2) with breast cancer risk and survival: the Breast Cancer Health Disparities Study.	Slattery ML et al.	2013	Breast cancer research and treatment
23949966	Search for genetic modifiers of IRF6 and genotype-phenotype correlations in Van der Woude and popliteal pterygium syndromes.	Leslie EJ et al.	2013	American journal of medical genetics. Part A
24025454	Hereditary breast cancer: ever more pieces to the polygenic puzzle.	Bogdanova N et al.	2013	Hereditary cancer in clinical practice
24054997	Association between rs2981582 polymorphism in the FGFR2 gene and the risk of breast cancer in Mexican women.	Murillo-Zamora E et al.	2013	Archives of medical research
24171766	Common low-penetrance risk variants associated with breast cancer in Polish women.	Ledwoń JK et al.	2013	BMC cancer
24218030	Replication of breast cancer susceptibility loci in whites and African Americans using a Bayesian approach.	O'Brien KM et al.	2014	American journal of epidemiology
24266904	Breast cancer prediction using genome wide single nucleotide polymorphism data.	Hajiloo M et al.	2013	BMC bioinformatics
24340245	Adiposity, inflammation, genetic variants and risk of post-menopausal breast cancer findings from a prospective-specimen-collection, retrospective-blinded-evaluation (PRoBE) design approach.	Yan XS et al.	2013	SpringerPlus
24359602	Common breast cancer risk variants in the post-COGS era: a comprehensive review.	Maxwell KN et al.	2013	Breast cancer research
24373701	Breast cancer susceptibility loci in association with age at menarche, age at natural menopause and the reproductive lifespan.	Warren Andersen S et al.	2014	Cancer epidemiology
24454457	Case-control study on the fibroblast growth factor receptor 2 gene polymorphisms associated with breast cancer in chinese han women.	Liu CL et al.	2013	Journal of breast cancer
24510657	Evaluating 17 breast cancer susceptibility loci in the Nashville breast health study.	Han MR et al.	2015	Breast cancer (Tokyo, Japan)
24771903	Breast Cancer Risk - From Genetics to Molecular Understanding of Pathogenesis.	Fasching PA et al.	2013	Geburtshilfe und Frauenheilkunde
24792587	Reproductive windows, genetic loci, and breast cancer risk.	Warren Andersen S et al.	2014	Annals of epidemiology
24832084	Cross-cancer pleiotropic analysis of endometrial cancer: PAGE and E2C2 consortia.	Setiawan VW et al.	2014	Carcinogenesis
24895409	Post-GWAS gene-environment interplay in breast cancer: results from the Breast and Prostate Cancer Cohort Consortium and a meta-analysis on 79,000 women.	Barrdahl M et al.	2014	Human molecular genetics
24941967	Breast cancer risk assessment using genetic variants and risk factors in a Singapore Chinese population.	Lee CP et al.	2014	Breast cancer research
25027274	Testing calibration of risk models at extremes of disease risk.	Song M et al.	2015	Biostatistics (Oxford, England)
25057183	A robust association test for detecting genetic variants with heterogeneous effects.	Yu K et al.	2015	Biostatistics (Oxford, England)
25253900	Breast Cancer Risk - Genes, Environment and Clinics.	Fasching PA et al.	2011	Geburtshilfe und Frauenheilkunde
25255808	Additive interactions between susceptibility single-nucleotide polymorphisms identified in genome-wide association studies and breast cancer risk factors in the Breast and Prostate Cancer Cohort Consortium.	Joshi AD et al.	2014	American journal of epidemiology
25270516	Association of physical activity and polymorphisms in FGFR2 and DNA methylation related genes with breast cancer risk.	Xi J et al.	2014	Cancer epidemiology
25333473	A study on genetic variants of Fibroblast growth factor receptor 2 (FGFR2) and the risk of breast cancer from North India.	Siddiqui S et al.	2014	PloS one
25611573	Association of breast cancer risk loci with breast cancer survival.	Barrdahl M et al.	2015	International journal of cancer
25677745	Rationale for targeting fibroblast growth factor receptor signaling in breast cancer.	André F et al.	2015	Breast cancer research and treatment
26070784	Genetic risk variants associated with in situ breast cancer.	Campa D et al.	2015	Breast cancer research
26113264	Functional annotation of HOT regions in the human genome: implications for human disease and cancer.	Li H et al.	2015	Scientific reports
26157456	Using parental phenotypes in case-parent studies.	Shi M et al.	2015	Frontiers in genetics
26379965	Associations of immunity-related single nucleotide polymorphisms with overall survival among prostate cancer patients.	Miles FL et al.	2015	International journal of clinical and experimental medicine
26421298	Heterogeneity of Breast Cancer Associations with Common Genetic Variants in FGFR2 according to the Intrinsic Subtypes in Southern Han Chinese Women.	Liang H et al.	2015	BioMed research international
26559640	Automated amplicon design suitable for analysis of DNA variants by melting techniques.	Ekstrøm PO et al.	2015	BMC research notes
26728143	Variants of FGFR2 and their associations with breast cancer risk: a HUGE systematic review and meta-analysis.	Cui F et al.	2016	Breast cancer research and treatment
26770289	Association of polymorphisms with a family history of cancer and the presence of germline mutations in the BRCA1/BRCA2 genes.	Fernandes GC et al.	2016	Hereditary cancer in clinical practice
26803517	Relationship between five GWAS-identified single nucleotide polymorphisms and female breast cancer in the Chinese Han population.	He Y et al.	2016	Tumour biology
26866629	Using family members to augment genetic case-control studies of a life-threatening disease.	Chen L et al.	2016	Statistics in medicine
26884359	Genetic predisposition to ductal carcinoma in situ of the breast.	Petridis C et al.	2016	Breast cancer research
26911390	TNRC9 rs12443621 and FGFR2 rs2981582 polymorphisms and breast cancer risk.	Chen Y et al.	2016	World journal of surgical oncology
27079684	Genome-wide association studies and epigenome-wide association studies go together in cancer control.	Verma M et al.	2016	Future oncology (London, England)
27121612	Text mining for precision medicine: automating disease-mutation relationship extraction from biomedical literature.	Singhal A et al.	2016	Journal of the American Medical Informatics Association
27236187	FGFR2 risk SNPs confer breast cancer risk by augmenting oestrogen responsiveness.	Campbell TM et al.	2016	Carcinogenesis
27572905	Genetic variants in FGFR2 and TNRC9 genes are associated with breast cancer risk in Pakistani women.	Mazhar A et al.	2016	Molecular medicine reports
27708667	Admixture Mapping of African-American Women in the AMBER Consortium Identifies New Loci for Breast Cancer and Estrogen-Receptor Subtypes.	Ruiz-Narváez EA et al.	2016	Frontiers in genetics
27825120	Trans-ethnic follow-up of breast cancer GWAS hits using the preferential linkage disequilibrium approach.	Zhu Q et al.	2016	Oncotarget
28098224	Association of Genome-Wide Association Study (GWAS) Identified SNPs and Risk of Breast Cancer in an Indian Population.	Nagrani R et al.	2017	Scientific reports
28117391	Functional PTGS2 polymorphism-based models as novel predictive markers in metastatic renal cell carcinoma patients receiving first-line sunitinib.	Cebrián A et al.	2017	Scientific reports
28178648	Polymorphisms of ESR1, UGT1A1, HCN1, MAP3K1 and CYP2B6 are associated with the prognosis of hormone receptor-positive early breast cancer.	Kuo SH et al.	2017	Oncotarget
28205043	A polygenic risk score for breast cancer risk in a Taiwanese population.	Hsieh YC et al.	2017	Breast cancer research and treatment
28521414	Association of FGFR2 rs2981582, SIRT1 rs12778366, STAT3 rs744166 gene polymorphisms with pituitary adenoma.	Glebauskiene B et al.	2017	Oncology letters
28757652	Genetic Breast Cancer Susceptibility Variants and Prognosis in the Prospectively Randomized SUCCESS A Study.	Hein A et al.	2017	Geburtshilfe und Frauenheilkunde
28985766	Mutations in BRCA1, BRCA2 and other breast and ovarian cancer susceptibility genes in Central and South American populations.	Jara L et al.	2017	Biological research
29104507	Fibroblast Growth Factor Receptor 2 Signaling in Breast Cancer.	Lei H et al.	2017	International journal of biological sciences
29372690	Association of single nucleotide polymorphisms in FGF-RAS/MAP signalling cascade with breast cancer susceptibility.	Dankova Z et al.	2017	General physiology and biophysics
29382703	Common Genetic Variation and Breast Cancer Risk-Past, Present, and Future.	Lilyquist J et al.	2018	Cancer epidemiology, biomarkers & prevention
29433565	Genetic determinants of sporadic breast cancer in Sri Lankan women.	Sirisena ND et al.	2018	BMC cancer
29560110	Evaluation of three polygenic risk score models for the prediction of breast cancer risk in Singapore Chinese.	Chan CHT et al.	2018	Oncotarget
29652634	Emerging applications of genome-editing technology to examine functionality of GWAS-associated variants for complex traits.	Smith AJP et al.	2018	Physiological genomics
29709729	Smoking and FGFR2 rs2981582 variant independently modulate male breast cancer survival: A population-based study in Tuscany, Italy.	Zanna I et al.	2018	Breast (Edinburgh, Scotland)
29872343	Association of FGFR2 and PI3KCA genetic variants with the risk of breast cancer in a Chinese population.	Wang Y et al.	2018	Cancer management and research
30206133	FGFR2 gene polymorphism rs2981582 is associated with non-functioning pituitary adenomas in Chinese Han population: a case-control study.	Zhu B et al.	2018	Bioscience reports
30285756	Subtype-specific associations between breast cancer risk polymorphisms and the survival of early-stage breast cancer.	Fu F et al.	2018	Journal of translational medicine
30359238	Effects of FGFR gene polymorphisms on response and toxicity of cyclophosphamide-epirubicin-docetaxel-based chemotherapy in breast cancer patients.	Chen L et al.	2018	BMC cancer
30399423	SIRT1 rs12778366, FGFR2 rs2981582, STAT3 rs744166, LIPC rs10468017, rs493258 and LPL rs12678919 genotypes and haplotype evaluation in patients with age-related macular degeneration.	Liutkeviciene R et al.	2019	Gene
30527746	Fibroblast Growth Factor Receptor-2 Polymorphism rs2981582 is Correlated With Progression-free Survival and Overall Survival in Patients With Metastatic Clear-cell Renal Cell Carcinoma Treated With Sunitinib.	Vanmechelen M et al.	2019	Clinical genitourinary cancer
30594178	A genome wide SNP genotyping study in the Tunisian population: specific reporting on a subset of common breast cancer risk loci.	Hamdi Y et al.	2018	BMC cancer
30781715	Genetic Epidemiology of Breast Cancer in Latin America.	Zavala VA et al.	2019	Genes
31002855	Predictive accuracy of the breast cancer genetic risk model based on eight common genetic variants: The BACkSIDE study.	Danková Z et al.	2019	Journal of biotechnology
31113874	The association of genetic variants in FGFR2 with osteoporosis susceptibility in Chinese Han population.	Yang Y et al.	2019	Bioscience reports
31125336	Evaluation of significant genome-wide association studies risk - SNPs in young breast cancer patients.	Rath M et al.	2019	PloS one
31142340	FGFs/FGFRs-dependent signalling in regulation of steroid hormone receptors - implications for therapy of luminal breast cancer.	Piasecka D et al.	2019	Journal of experimental & clinical cancer research
31199170	Does CETP rs5882, rs708272, SIRT1 rs12778366, FGFR2 rs2981582, STAT3 rs744166, VEGFA rs833068, IL6 rs1800795 polymorphisms play a role in optic neuritis development?	Gedvilaite G et al.	2019	Ophthalmic genetics
31448667	Correlation of FGFR2 rs2981582 polymorphisms with susceptibility to breast cancer: a case-control study in a Chinese population.	Shu J et al.	2019	The Journal of international medical research
31759353	P21 Ser31Arg and FGFR2 rs2981582 Polymorphisms as Risk Factors for Early Onset of Breast Cancer in Yogyakarta, Indonesia.	Purnomosari D et al.	2019	Asian Pacific journal of cancer prevention
31781300	Determination of SIRT1 rs12778366, FGFR2 rs2981582, STAT3 rs744166, and RAGE rs1800625 Single Gene Polymorphisms in Patients with Laryngeal Squamous Cell Carcinoma.	Uloza V et al.	2019	Disease markers
32269954	Copy number alternations of the 17q23-rs6504950 locus are associated with advanced breast cancers in Taiwanese women.	Lin CY et al.	2020	Ci ji yi xue za zhi = Tzu-chi medical journal
32287273	DOT: Gene-set analysis by combining decorrelated association statistics.	Vsevolozhskaya OA et al.	2020	PLoS computational biology
32366738	Low-penetrance susceptibility variants and postmenopausal oestrogen receptor positive breast cancer.	Özgöz A et al.	2020	Journal of genetics
32487238	MassARRAY analysis of twelve cancer related SNPs in esophageal squamous cell carcinoma in J&K, India.	Shah R et al.	2020	BMC cancer
32547144	Genetic Association of SH2B1 Gene Polymorphisms in Jordanian Arab Patients with Type 2 Diabetes Mellitus.	Al-Eitan LN et al.	2020	Diabetes, metabolic syndrome and obesity
32706340	Tendencies of FGFR2 rs2981582 polymorphism in patients with oral cancer.	Liutkevicius V et al.	2020	Stomatologija
32894086	MassARRAY-based single nucleotide polymorphism analysis in breast cancer of north Indian population.	Bakshi D et al.	2020	BMC cancer
33081025	The FGF/FGFR System in Breast Cancer: Oncogenic Features and Therapeutic Perspectives.	Santolla MF et al.	2020	Cancers
33112566	The Associations of Common Genetic Susceptibility Variants with Breast Cancer in Jordanian Arabs: A Case-Control Study.	Al-Eitan LN et al.	2020	Asian Pacific journal of cancer prevention
33126731	Genomic Diversity in Sporadic Breast Cancer in a Latin American Population.	Brignoni L et al.	2020	Genes
33659210	A Review of Cancer Genetics and Genomics Studies in Africa.	Rotimi SO et al.	2020	Frontiers in oncology
33740609	Genetic polymorphism of fibroblast growth factor receptor 2 and trinucleotide repeat-containing 9 influence the susceptibility to HCV-induced hepatocellular carcinoma.	Al-Khaykanee AM et al.	2021	Clinics and research in hepatology and gastroenterology
33762959	Meta-Analysis of ABCG2 and ABCB1 Polymorphisms With Sunitinib-Induced Toxicity and Efficacy in Renal Cell Carcinoma.	Sun F et al.	2021	Frontiers in pharmacology
34359697	A Personal Breast Cancer Risk Stratification Model Using Common Variants and Environmental Risk Factors in Japanese Females.	Oze I et al.	2021	Cancers
34514747	Activation of FGFR2 Signaling Suppresses BRCA1 and Drives Triple-Negative Mammary Tumorigenesis That is Sensitive to Immunotherapy.	Lei JH et al.	2021	Advanced science (Weinheim, Baden-Wurttemberg, Germany)
34759736	Fibroblast growth factor receptor 2 gene (FGFR2) rs2981582T/C polymorphism and susceptibility to breast cancer in Saudi women.	AlRaddadi RIR et al.	2021	Saudi journal of biological sciences
34830836	Biological Significance and Targeting of the FGFR Axis in Cancer.	Chioni AM et al.	2021	Cancers
35395775	Development and validation of polygenic risk scores for prediction of breast cancer and breast cancer subtypes in Chinese women.	Hou C et al.	2022	BMC cancer
35406617	Germline Variants in Angiogenesis-Related Genes Contribute to Clinical Outcome in Head and Neck Squamous Cell Carcinoma.	Butkiewicz D et al.	2022	Cancers
35672017	COL1A1 and FGFR2 Single-Nucleotide Polymorphisms Found in Class II and Class III Skeletal Malocclusions in Javanese Population.	Ardani IGAW et al.	2023	European journal of dentistry

The Flanks tab provides retrieving flanking sequences of a SNP on all molecules that have placements.

Genome context:

Select flank length:

Genomic regions, transcripts, and products
Top▲ Help
NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
Visit Sequence Viewer for help with navigating inside the display and modifying the selection of displayed data tracks.

Choose placement

dbSNP Short Genetic Variations

Welcome to the Reference SNP (rs) Report

Reference SNP (rs) Report

rs2981582