Name: rs2004776
Published: September 21, 2022
License: Open Access

Welcome to the Reference SNP (rs) Report

All alleles are reported in the Forward orientation. Click on the Variant Details tab for details on Genomic Placement, Gene, and Amino Acid changes. HGVS names are in the HGVS tab.

Reference SNP (rs) Report

This page reports data for a single dbSNP Reference SNP variation (RefSNP or rs) from the new redesigned dbSNP build.
Top of the page reports a concise summary for the rs, with more specific details included in the corresponding tabs below.
All alleles are reported in the Forward orientation. Use the Genomic View to inspect the nucleotides flanking the variant, and its neighbors.
For more information see Help documentation.

rs2004776

Current Build 156

Released September 21, 2022

Organism: Homo sapiens
Position: chr1:230712956 (GRCh38.p14) Help
The anchor position for this RefSNP. Includes all nucleotides potentially affected by this change, thus it can differ from HGVS, which is right-shifted. See here for details.
Alleles: C>G / C>T
Variation Type: SNV Single Nucleotide Variation
Frequency: T=0.341985 (90520/264690, TOPMED)
T=0.244171 (34979/143256, ALFA)
C=0.38356 (10838/28256, 14KJPN) (+ 18 more)
C=0.38371 (6431/16760, 8.3KJPN)
T=0.4026 (2578/6404, 1000G_30x)
T=0.4101 (2054/5008, 1000G)
T=0.2527 (1132/4480, Estonian)
T=0.2361 (910/3854, ALSPAC)
T=0.2438 (904/3708, TWINSUK)
C=0.4096 (1200/2930, KOREAN)
T=0.4360 (825/1892, HapMap)
C=0.3728 (683/1832, Korea1K)
T=0.235 (235/998, GoNL)
C=0.430 (339/788, PRJEB37584)
T=0.235 (141/600, NorthernSweden)
C=0.355 (108/304, SGDP_PRJ)
T=0.245 (53/216, Qatari)
C=0.369 (79/214, Vietnamese)
T=0.36 (33/92, PharmGKB)
T=0.15 (6/40, GENOME_DK)
C=0.40 (12/30, Siberian)

Clinical Significance: Reported in ClinVar
Gene : Consequence: AGT : Intron Variant
Publications: 8 citations
Genomic View: See rs on genome

ALFA Allele Frequency
The ALFA project provide aggregate allele frequency from dbGaP. More information is available on the project page including descriptions, data access, and terms of use.

Release Version: 20231103111315

Population	Group	Sample Size	Ref Allele	Alt Allele	Ref HMOZ	Alt HMOZ	HTRZ	HWEP
Total	Global	143256	C=0.755829	G=0.000000, T=0.244171	0.576883	0.065226	0.357891	34
European	Sub	125378	C=0.769034	G=0.000000, T=0.230966	0.594091	0.056023	0.349886	8
African	Sub	4680	C=0.6327	G=0.0000, T=0.3673	0.432479	0.167094	0.400427	24
African Others	Sub	168	C=0.595	G=0.000, T=0.405	0.404762	0.214286	0.380952	2
African American	Sub	4512	C=0.6341	G=0.0000, T=0.3659	0.433511	0.165337	0.401152	22
Asian	Sub	540	C=0.467	G=0.000, T=0.533	0.222222	0.288889	0.488889	0
East Asian	Sub	424	C=0.439	G=0.000, T=0.561	0.183962	0.306604	0.509434	0
Other Asian	Sub	116	C=0.569	G=0.000, T=0.431	0.362069	0.224138	0.413793	1
Latin American 1	Sub	658	C=0.669	G=0.000, T=0.331	0.455927	0.118541	0.425532	0
Latin American 2	Sub	5942	C=0.6393	G=0.0000, T=0.3607	0.411982	0.133288	0.454729	0
South Asian	Sub	136	C=0.757	G=0.000, T=0.243	0.588235	0.073529	0.338235	0
Other	Sub	5922	C=0.7264	G=0.0000, T=0.2736	0.537656	0.084769	0.377575	5

Frequency tab displays a table of the reference and alternate allele frequencies reported by various studies and populations. Table lines, where Population="Global" refer to the entire study population, whereas lines, where Group="Sub", refer to a study-specific population subgroupings (i.e. AFR, CAU, etc.), if available. Frequency for the alternate allele (Alt Allele) is a ratio of samples observed-to-total, where the numerator (observed samples) is the number of chromosomes in the study with the minor allele present (found in "Sample size", where Group="Sub"), and the denominator (total samples) is the total number of all chromosomes in the study for the variant (found in "Sample size", where Group="Study-wide" and Population="Global").

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Study	Population	Group	Sample Size	Ref Allele	Alt Allele
TopMed	Global	Study-wide	264690	C=0.658015	T=0.341985
Allele Frequency Aggregator	Total	Global	143256	C=0.755829	G=0.000000, T=0.244171
Allele Frequency Aggregator	European	Sub	125378	C=0.769034	G=0.000000, T=0.230966
Allele Frequency Aggregator	Latin American 2	Sub	5942	C=0.6393	G=0.0000, T=0.3607
Allele Frequency Aggregator	Other	Sub	5922	C=0.7264	G=0.0000, T=0.2736
Allele Frequency Aggregator	African	Sub	4680	C=0.6327	G=0.0000, T=0.3673
Allele Frequency Aggregator	Latin American 1	Sub	658	C=0.669	G=0.000, T=0.331
Allele Frequency Aggregator	Asian	Sub	540	C=0.467	G=0.000, T=0.533
Allele Frequency Aggregator	South Asian	Sub	136	C=0.757	G=0.000, T=0.243
14KJPN	JAPANESE	Study-wide	28256	C=0.38356	T=0.61644
8.3KJPN	JAPANESE	Study-wide	16760	C=0.38371	T=0.61629
1000Genomes_30x	Global	Study-wide	6404	C=0.5974	T=0.4026
1000Genomes_30x	African	Sub	1786	C=0.5218	T=0.4782
1000Genomes_30x	Europe	Sub	1266	C=0.7757	T=0.2243
1000Genomes_30x	South Asian	Sub	1202	C=0.6248	T=0.3752
1000Genomes_30x	East Asian	Sub	1170	C=0.4359	T=0.5641
1000Genomes_30x	American	Sub	980	C=0.664	T=0.336
1000Genomes	Global	Study-wide	5008	C=0.5899	T=0.4101
1000Genomes	African	Sub	1322	C=0.5129	T=0.4871
1000Genomes	East Asian	Sub	1008	C=0.4236	T=0.5764
1000Genomes	Europe	Sub	1006	C=0.7744	T=0.2256
1000Genomes	South Asian	Sub	978	C=0.621	T=0.379
1000Genomes	American	Sub	694	C=0.667	T=0.333
Genetic variation in the Estonian population	Estonian	Study-wide	4480	C=0.7473	T=0.2527
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	C=0.7639	T=0.2361
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	C=0.7562	T=0.2438
KOREAN population from KRGDB	KOREAN	Study-wide	2930	C=0.4096	T=0.5904
HapMap	Global	Study-wide	1892	C=0.5640	T=0.4360
HapMap	American	Sub	770	C=0.630	T=0.370
HapMap	African	Sub	692	C=0.517	T=0.483
HapMap	Asian	Sub	254	C=0.339	T=0.661
HapMap	Europe	Sub	176	C=0.784	T=0.216
Korean Genome Project	KOREAN	Study-wide	1832	C=0.3728	T=0.6272
Genome of the Netherlands Release 5	Genome of the Netherlands	Study-wide	998	C=0.765	T=0.235
CNV burdens in cranial meningiomas	Global	Study-wide	788	C=0.430	T=0.570
CNV burdens in cranial meningiomas	CRM	Sub	788	C=0.430	T=0.570
Northern Sweden	ACPOP	Study-wide	600	C=0.765	T=0.235
SGDP_PRJ	Global	Study-wide	304	C=0.355	T=0.645
Qatari	Global	Study-wide	216	C=0.755	T=0.245
A Vietnamese Genetic Variation Database	Global	Study-wide	214	C=0.369	T=0.631
PharmGKB Aggregated	Global	Study-wide	92	C=0.64	T=0.36
PharmGKB Aggregated	PA151491714	Sub	92	C=0.64	T=0.36
The Danish reference pan genome	Danish	Study-wide	40	C=0.85	T=0.15
Siberian	Global	Study-wide	30	C=0.40	T=0.60

Variant Details tab shows known variant placements on genomic sequences: chromosomes (NC_), RefSeqGene, pseudogenes or genomic regions (NG_), and in a separate table: on transcripts (NM_) and protein sequences (NP_). The corresponding transcript and protein locations are listed in adjacent lines, along with molecular consequences from Sequence Ontology. When no protein placement is available, only the transcript is listed. Column "Codon[Amino acid]" shows the actual base change in the format of "Reference > Alternate" allele, including the nucleotide codon change in transcripts, and the amino acid change in proteins, respectively, allowing for known ribosomal slippage sites. To view nucleotides adjacent to the variant use the Genomic View at the bottom of the page - zoom into the sequence until the nucleotides around the variant become visible.

Genomic Placements

Sequence name	Change
GRCh38.p14 chr 1	NC_000001.11:g.230712956C>G
GRCh38.p14 chr 1	NC_000001.11:g.230712956C>T
GRCh37.p13 chr 1	NC_000001.10:g.230848702C>G
GRCh37.p13 chr 1	NC_000001.10:g.230848702C>T
AGT RefSeqGene	NG_008836.2:g.6635G>C
AGT RefSeqGene	NG_008836.2:g.6635G>A

Gene: AGT, angiotensinogen (minus strand)

Molecule type	Change	Amino acid[Codon]	SO Term
AGT transcript variant 2	NM_001382817.3:c.-30-2103… NM_001382817.3:c.-30-2103G>C	N/A	Intron Variant
AGT transcript variant 1	NM_001384479.1:c.-31+1130… NM_001384479.1:c.-31+1130G>C	N/A	Intron Variant

Clinical Significance tab shows a list of clinical significance entries from ClinVar associated with the variation, per allele. Click on the RCV accession (i.e. RCV000001615.2) or Allele ID (i.e. 12274) to access full ClinVar report.

Allele: T (allele ID: 1247924 )

ClinVar Accession	Disease Names	Clinical Significance
RCV001670960.2	not provided	Benign

Aliases tab displays HGVS names representing the variant placements and allele changes on genomic, transcript and protein sequences, per allele. HGVS name is an expression for reporting sequence accession and version, sequence type, position, and allele change. The column "Note" can have two values: "diff" means that there is a difference between the reference allele (variation interval) at the placement reported in HGVS name and the reference alleles reported in other HGVS names, and "rev" means that the sequence of this variation interval at the placement reported in HGVS name is in reverse orientation to the sequence(s) of this variation in other HGVS names not labeled as "rev".

Placement	C=	G	T
GRCh38.p14 chr 1	NC_000001.11:g.230712956=	NC_000001.11:g.230712956C>G	NC_000001.11:g.230712956C>T
GRCh37.p13 chr 1	NC_000001.10:g.230848702=	NC_000001.10:g.230848702C>G	NC_000001.10:g.230848702C>T
AGT RefSeqGene	NG_008836.2:g.6635=	NG_008836.2:g.6635G>C	NG_008836.2:g.6635G>A
AGT transcript	NM_000029.3:c.-4+1130=	NM_000029.3:c.-4+1130G>C	NM_000029.3:c.-4+1130G>A
AGT transcript variant 2	NM_001382817.3:c.-30-2103=	NM_001382817.3:c.-30-2103G>C	NM_001382817.3:c.-30-2103G>A
AGT transcript variant 1	NM_001384479.1:c.-31+1130=	NM_001384479.1:c.-31+1130G>C	NM_001384479.1:c.-31+1130G>A

Submissions tab displays variations originally submitted to dbSNP, now supporting this RefSNP cluster (rs). We display Submitter handle, Submission identifier, Date and Build number, when the submission appeared for the first time. Direct submissions to dbSNP have Submission ID in the form of an ss-prefixed number (ss#). Other supporting variations are listed in the table without ss#.

109 SubSNP, 23 Frequency, 1 ClinVar submissions

No	Submitter	Submission ID	Date (Build)
1	TSC-CSHL	ss2920537	Jan 12, 2001 (92)
2	SC_JCM	ss6121779	Feb 20, 2003 (111)
3	WI_SSAHASNP	ss6695689	Feb 20, 2003 (111)
4	BCM_SSAHASNP	ss9898828	Jul 11, 2003 (116)
5	WI_SSAHASNP	ss11424811	Jul 11, 2003 (116)
6	PARC	ss16338945	Feb 27, 2004 (120)
7	CSHL-HAPMAP	ss16430270	Feb 27, 2004 (120)
8	PERLEGEN	ss23884999	Sep 20, 2004 (123)
9	ABI	ss44006417	Mar 15, 2006 (126)
10	PERLEGEN	ss68795940	May 18, 2007 (127)
11	ILLUMINA	ss75036773	Dec 07, 2007 (129)
12	KRIBB_YJKIM	ss80732287	Dec 14, 2007 (130)
13	PHARMGKB_PARC	ss84151291	Dec 14, 2007 (130)
14	BGI	ss102830766	Dec 01, 2009 (131)
15	1000GENOMES	ss109021209	Jan 23, 2009 (130)
16	1000GENOMES	ss111914193	Jan 25, 2009 (130)
17	ILLUMINA-UK	ss119241036	Feb 15, 2009 (130)
18	KRIBB_YJKIM	ss119411769	Dec 01, 2009 (131)
19	GMI	ss156402021	Dec 01, 2009 (131)
20	ILLUMINA	ss160487469	Dec 01, 2009 (131)
21	ENSEMBL	ss161227508	Dec 01, 2009 (131)
22	COMPLETE_GENOMICS	ss165368994	Jul 04, 2010 (132)
23	COMPLETE_GENOMICS	ss167558906	Jul 04, 2010 (132)
24	ILLUMINA	ss173039483	Jul 04, 2010 (132)
25	BUSHMAN	ss199729338	Jul 04, 2010 (132)
26	1000GENOMES	ss218933427	Jul 14, 2010 (132)
27	1000GENOMES	ss230940970	Jul 14, 2010 (132)
28	1000GENOMES	ss238547526	Jul 15, 2010 (132)
29	ILLUMINA	ss244286121	Jul 04, 2010 (132)
30	BL	ss253884109	May 09, 2011 (134)
31	GMI	ss276256134	May 04, 2012 (137)
32	PJP	ss290753207	May 09, 2011 (134)
33	ILLUMINA	ss480377941	May 04, 2012 (137)
34	ILLUMINA	ss480390368	May 04, 2012 (137)
35	ILLUMINA	ss481165333	Sep 08, 2015 (146)
36	ILLUMINA	ss484986554	May 04, 2012 (137)
37	ILLUMINA	ss537021607	Sep 08, 2015 (146)
38	TISHKOFF	ss555199761	Apr 25, 2013 (138)
39	SSMP	ss648772947	Apr 25, 2013 (138)
40	ILLUMINA	ss778476225	Aug 21, 2014 (142)
41	ILLUMINA	ss782939592	Aug 21, 2014 (142)
42	ILLUMINA	ss783902214	Aug 21, 2014 (142)
43	ILLUMINA	ss832195170	Apr 01, 2015 (144)
44	ILLUMINA	ss833932048	Aug 21, 2014 (142)
45	EVA-GONL	ss976246027	Aug 21, 2014 (142)
46	JMKIDD_LAB	ss1068678328	Aug 21, 2014 (142)
47	1000GENOMES	ss1295035025	Aug 21, 2014 (142)
48	DDI	ss1426140702	Apr 01, 2015 (144)
49	EVA_GENOME_DK	ss1574742370	Apr 01, 2015 (144)
50	EVA_DECODE	ss1585645952	Apr 01, 2015 (144)
51	EVA_UK10K_ALSPAC	ss1602344813	Apr 01, 2015 (144)
52	EVA_UK10K_TWINSUK	ss1645338846	Apr 01, 2015 (144)
53	EVA_SVP	ss1712412880	Apr 01, 2015 (144)
54	ILLUMINA	ss1751904345	Sep 08, 2015 (146)
55	HAMMER_LAB	ss1795862175	Sep 08, 2015 (146)
56	WEILL_CORNELL_DGM	ss1919467704	Feb 12, 2016 (147)
57	GENOMED	ss1966996821	Jul 19, 2016 (147)
58	JJLAB	ss2020259084	Sep 14, 2016 (149)
59	USC_VALOUEV	ss2148294826	Dec 20, 2016 (150)
60	HUMAN_LONGEVITY	ss2170880683	Dec 20, 2016 (150)
61	SYSTEMSBIOZJU	ss2624641489	Nov 08, 2017 (151)
62	ILLUMINA	ss2632641557	Nov 08, 2017 (151)
63	GRF	ss2698294663	Nov 08, 2017 (151)
64	GNOMAD	ss2767311829	Nov 08, 2017 (151)
65	SWEGEN	ss2988609595	Nov 08, 2017 (151)
66	BIOINF_KMB_FNS_UNIBA	ss3023890149	Nov 08, 2017 (151)
67	CSHL	ss3343956729	Nov 08, 2017 (151)
68	ILLUMINA	ss3626330664	Oct 11, 2018 (152)
69	ILLUMINA	ss3630670736	Oct 11, 2018 (152)
70	ILLUMINA	ss3632929025	Oct 11, 2018 (152)
71	ILLUMINA	ss3633625258	Oct 11, 2018 (152)
72	ILLUMINA	ss3634378002	Oct 11, 2018 (152)
73	ILLUMINA	ss3635318271	Oct 11, 2018 (152)
74	ILLUMINA	ss3636056987	Oct 11, 2018 (152)
75	ILLUMINA	ss3637068827	Oct 11, 2018 (152)
76	ILLUMINA	ss3637819741	Oct 11, 2018 (152)
77	ILLUMINA	ss3640085355	Oct 11, 2018 (152)
78	ILLUMINA	ss3642825686	Oct 11, 2018 (152)
79	EGCUT_WGS	ss3656568015	Jul 12, 2019 (153)
80	EVA_DECODE	ss3688819251	Jul 12, 2019 (153)
81	ACPOP	ss3727946132	Jul 12, 2019 (153)
82	ILLUMINA	ss3744678849	Jul 12, 2019 (153)
83	EVA	ss3747457666	Jul 12, 2019 (153)
84	ILLUMINA	ss3772179722	Jul 12, 2019 (153)
85	KHV_HUMAN_GENOMES	ss3800459364	Jul 12, 2019 (153)
86	EVA	ss3826693725	Apr 25, 2020 (154)
87	EVA	ss3836748600	Apr 25, 2020 (154)
88	EVA	ss3842161011	Apr 25, 2020 (154)
89	SGDP_PRJ	ss3851098756	Apr 25, 2020 (154)
90	KRGDB	ss3896445055	Apr 25, 2020 (154)
91	KOGIC	ss3946693288	Apr 25, 2020 (154)
92	EVA	ss3984473614	Apr 25, 2021 (155)
93	TOPMED	ss4486958443	Apr 25, 2021 (155)
94	TOMMO_GENOMICS	ss5148875882	Apr 25, 2021 (155)
95	1000G_HIGH_COVERAGE	ss5246131839	Oct 12, 2022 (156)
96	EVA	ss5314689855	Oct 12, 2022 (156)
97	EVA	ss5325404550	Oct 12, 2022 (156)
98	HUGCELL_USP	ss5446534206	Oct 12, 2022 (156)
99	EVA	ss5506224006	Oct 12, 2022 (156)
100	1000G_HIGH_COVERAGE	ss5520399093	Oct 12, 2022 (156)
101	SANFORD_IMAGENETICS	ss5624232550	Oct 12, 2022 (156)
102	SANFORD_IMAGENETICS	ss5627637428	Oct 12, 2022 (156)
103	TOMMO_GENOMICS	ss5676765022	Oct 12, 2022 (156)
104	EVA	ss5799514634	Oct 12, 2022 (156)
105	YY_MCH	ss5801725140	Oct 12, 2022 (156)
106	EVA	ss5833398180	Oct 12, 2022 (156)
107	EVA	ss5849328471	Oct 12, 2022 (156)
108	EVA	ss5912361162	Oct 12, 2022 (156)
109	EVA	ss5939485175	Oct 12, 2022 (156)
110	1000Genomes	NC_000001.10 - 230848702	Oct 11, 2018 (152)
111	1000Genomes_30x	NC_000001.11 - 230712956	Oct 12, 2022 (156)
112	The Avon Longitudinal Study of Parents and Children	NC_000001.10 - 230848702	Oct 11, 2018 (152)
113	Genetic variation in the Estonian population	NC_000001.10 - 230848702	Oct 11, 2018 (152)
114	The Danish reference pan genome	NC_000001.10 - 230848702	Apr 25, 2020 (154)
115	gnomAD - Genomes Submission ignored due to conflicting rows: Row 42361940 (NC_000001.11:230712955:C:G 3/139998) Row 42361941 (NC_000001.11:230712955:C:T 44892/139946)	-	Apr 25, 2021 (155)
116	gnomAD - Genomes Submission ignored due to conflicting rows: Row 42361940 (NC_000001.11:230712955:C:G 3/139998) Row 42361941 (NC_000001.11:230712955:C:T 44892/139946)	-	Apr 25, 2021 (155)
117	Genome of the Netherlands Release 5	NC_000001.10 - 230848702	Apr 25, 2020 (154)
118	HapMap	NC_000001.11 - 230712956	Apr 25, 2020 (154)
119	KOREAN population from KRGDB	NC_000001.10 - 230848702	Apr 25, 2020 (154)
120	Korean Genome Project	NC_000001.11 - 230712956	Apr 25, 2020 (154)
121	Northern Sweden	NC_000001.10 - 230848702	Jul 12, 2019 (153)
122	CNV burdens in cranial meningiomas	NC_000001.10 - 230848702	Apr 25, 2021 (155)
123	PharmGKB Aggregated	NC_000001.11 - 230712956	Apr 25, 2020 (154)
124	Qatari	NC_000001.10 - 230848702	Apr 25, 2020 (154)
125	SGDP_PRJ	NC_000001.10 - 230848702	Apr 25, 2020 (154)
126	Siberian	NC_000001.10 - 230848702	Apr 25, 2020 (154)
127	8.3KJPN	NC_000001.10 - 230848702	Apr 25, 2021 (155)
128	14KJPN	NC_000001.11 - 230712956	Oct 12, 2022 (156)
129	TopMed	NC_000001.11 - 230712956	Apr 25, 2021 (155)
130	UK 10K study - Twins	NC_000001.10 - 230848702	Oct 11, 2018 (152)
131	A Vietnamese Genetic Variation Database	NC_000001.10 - 230848702	Jul 12, 2019 (153)
132	ALFA	NC_000001.11 - 230712956	Apr 25, 2021 (155)
133	ClinVar	RCV001670960.2	Oct 12, 2022 (156)

History tab displays RefSNPs (Associated ID) from previous builds (Build) that now support the current RefSNP, and the dates, when the history was updated for each Associated ID (History Updated).

Associated ID	History Updated (Build)
rs16852395	Oct 07, 2004 (123)
rs56939563	May 23, 2008 (130)
rs386552255	Aug 21, 2014 (142)

Added to this RefSNP Cluster:

Submission IDs	Observation SPDI	Canonical SPDI	Source RSIDs
15963244449	NC_000001.11:230712955:C:G	NC_000001.11:230712955:C:G	(self)
ss109021209, ss111914193, ss119241036, ss165368994, ss167558906, ss199729338, ss253884109, ss276256134, ss290753207, ss480377941, ss1585645952, ss1712412880, ss3642825686	NC_000001.9:228915324:C:T	NC_000001.11:230712955:C:T	(self)
5903510, 3264173, 2306263, 1925486, 1426402, 3622449, 1230997, 22935, 1509634, 3115736, 811180, 6845189, 3264173, 710016, ss218933427, ss230940970, ss238547526, ss480390368, ss481165333, ss484986554, ss537021607, ss555199761, ss648772947, ss778476225, ss782939592, ss783902214, ss832195170, ss833932048, ss976246027, ss1068678328, ss1295035025, ss1426140702, ss1574742370, ss1602344813, ss1645338846, ss1751904345, ss1795862175, ss1919467704, ss1966996821, ss2020259084, ss2148294826, ss2624641489, ss2632641557, ss2698294663, ss2767311829, ss2988609595, ss3343956729, ss3626330664, ss3630670736, ss3632929025, ss3633625258, ss3634378002, ss3635318271, ss3636056987, ss3637068827, ss3637819741, ss3640085355, ss3656568015, ss3727946132, ss3744678849, ss3747457666, ss3772179722, ss3826693725, ss3836748600, ss3851098756, ss3896445055, ss3984473614, ss5148875882, ss5314689855, ss5325404550, ss5506224006, ss5624232550, ss5627637428, ss5799514634, ss5833398180, ss5939485175	NC_000001.10:230848701:C:T	NC_000001.11:230712955:C:T	(self)
RCV001670960.2, 7925028, 288083, 3071289, 919, 10602126, 50564778, 15963244449, ss2170880683, ss3023890149, ss3688819251, ss3800459364, ss3842161011, ss3946693288, ss4486958443, ss5246131839, ss5446534206, ss5520399093, ss5676765022, ss5801725140, ss5849328471, ss5912361162	NC_000001.11:230712955:C:T	NC_000001.11:230712955:C:T	(self)
ss9898828, ss11424811	NT_021973.15:779690:C:T	NC_000001.11:230712955:C:T	(self)
ss16430270	NT_021973.16:779690:C:T	NC_000001.11:230712955:C:T	(self)
ss2920537, ss6121779, ss6695689, ss16338945, ss23884999, ss44006417, ss68795940, ss75036773, ss80732287, ss84151291, ss102830766, ss119411769, ss156402021, ss160487469, ss161227508, ss173039483, ss244286121	NT_167186.1:24366480:C:T	NC_000001.11:230712955:C:T	(self)

Publications tab displays PubMed articles citing the variation as a listing of PMID, Title, Author, Year, Journal, ordered by Year, descending.

8 citations for rs2004776

PMID	Title	Author	Year	Journal
19770777	Genotype-phenotype analysis of angiotensinogen polymorphisms and essential hypertension: the importance of haplotypes.	Watkins WS et al.	2010	Journal of hypertension
21306748	The association of the angiotensinogen gene with insulin sensitivity in humans: a tagging single nucleotide polymorphism and haplotype approach.	Underwood PC et al.	2011	Metabolism
21444836	Association of hypertension drug target genes with blood pressure and hypertension in 86,588 individuals.	Johnson AD et al.	2011	Hypertension (Dallas, Tex.
21953487	Beyond genome-wide association studies: new strategies for identifying genetic determinants of hypertension.	Wang X et al.	2011	Current hypertension reports
22100073	Blood pressure loci identified with a gene-centric array.	Johnson T et al.	2011	American journal of human genetics
28105631	Association of genetic variation with blood pressure traits among East Africans.	Kayima J et al.	2017	Clinical genetics
31201268	A polymorphism in intron I of the human angiotensinogen gene (hAGT) affects binding by HNF3 and hAGT expression and increases blood pressure in mice.	Mopidevi B et al.	2019	The Journal of biological chemistry
31469255	A genome-wide association and replication study of blood pressure in Ugandan early adolescents.	Lule SA et al.	2019	Molecular genetics & genomic medicine

The Flanks tab provides retrieving flanking sequences of a SNP on all molecules that have placements.

Genome context:

Select flank length:

Genomic regions, transcripts, and products
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NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
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dbSNP Short Genetic Variations

Welcome to the Reference SNP (rs) Report

Reference SNP (rs) Report

rs2004776