Gene Expression

Introduction

Gene expression

• the phenotypic manifestation of a gene or genes by the processes of genetic transcription and genetic translation.

Gene expression analysis

• the determination of the pattern of genes expressed at the level of genetic transcription, under specific circumstances or in a specific cell.

How It Works

When genes are expressed, the genetic information (base sequence) on DNA is first copied to a molecule of mRNA (transcription). The mRNA molecules then leave the cell nucleus and enter the cytoplasm, where they participate in protein synthesis by specifying the particular amino acids that make up individual proteins (translation).

Technologies

• Real Time quantitative RT-PCR
• In situ hybridization
• Microarrays
• Massively Parallel Signature Sequencing (MPSS)

Replace Me

Resources

» Entrez GEO - Gene Expression Omnibus- expression and molecular abundance profiles.

» GEO DataSets- experimental sets of GEO data.

» Digital Differential Display- expression analysis of EST libraries.

Included file 'applexpression-table1.inc' not found

Disclaimer

Mention of specific products or vendors on this website does not constitute an endorsement by the U.S. government.