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Select item 111504811.

In silico predicted compound targeting the IQGAP1-GRD domain selectively inhibits growth of human acute myeloid leukemia

Deepak M. Sahasrabudhe, Jane L. Liesveld, Mohammad Minhajuddin, Niloy A. Singh, Subhangi Nath, Vishuwes Muthu Kumar, Marlene Balys, Andrew G. Evans, Mitra Azadniv, Jeanne N. Hansen, Michael W. Becker, Ashoke Sharon, V. Kaye Thomas, Richard G. Moore, Manoj K. Khera, Craig T. Jordan, Rakesh K. Singh

Sci Rep. 2024; 14: 12868. Published online 2024 Jun 4. doi: 10.1038/s41598-024-63392-2

PMCID:: PMC11150481

Abstract Article PDF–6.8M

Select item 110374622.

Molecular and Functional Characterization of GABA Receptor Subunits GRD and LCCH3 from Human Louse Pediculus Humanus Humanus

Omar Hashim, Claude L. Charvet, Berthine Toubaté, Aimun A.E. Ahmed, Nicolas Lamassiaude, Cédric Neveu, Isabelle Dimier-Poisson, Françoise Debierre-Grockiego, Catherine Dupuy

Mol Pharmacol. 2022 Aug; 102(2): 116–127. Published online 2022 Aug. doi: 10.1124/molpharm.122.000499

PMCID:: PMC11037462

Abstract Article PDF–4.5M

Select item 74294803.

Heterogeneous expression of GABA receptor‐like subunits LCCH3 and GRD reveals functional diversity of GABA receptors in the honeybee Apis mellifera

Christopher Henry, Thierry Cens, Pierre Charnet, Catherine Cohen‐Solal, Claude Collet, Juliette van‐Dijk, Janique Guiramand, Marie‐céleste de Jésus‐Ferreira, Claudine Menard, Nawfel Mokrane, Julien Roussel, Jean‐Baptiste Thibault, Michel Vignes, Matthieu Rousset

Br J Pharmacol. 2020 Sep; 177(17): 3924–3940. Published online 2020 Jun 29. doi: 10.1111/bph.15135

Correction in:: Br J Pharmacol. 2020 Oct; 177(20): 4808.

PMCID:: PMC7429480

Abstract Article PDF–4.9M

Select item 65884234.

Feasibility of Using NF1-GRD and AAV for Gene Replacement Therapy in NF1-Associated Tumors

Ren-Yuan Bai, Dominic Esposito, Ada J. Tam, Frank McCormick, Gregory J. Riggins, D. Wade Clapp, Verena Staedtke

Gene Ther. Author manuscript; available in PMC 2019 Nov 24.

Published in final edited form as: Gene Ther. 2019 Jun; 26(6): 277–286. Published online 2019 May 24. doi: 10.1038/s41434-019-0080-9

PMCID:: PMC6588423

Abstract Article PDF–1.5M

Select item 62099765.

An Operational Tool for the Automatic Detection and Removal of Border Noise in Sentinel-1 GRD Products

Mattia Stasolla, Xavier Neyt

Sensors (Basel) 2018 Oct; 18(10): 3454. Published online 2018 Oct 14. doi: 10.3390/s18103454

PMCID:: PMC6209976

Abstract Article PDF–6.1M

Select item 32686856.

Schweinfurthin A Selectively Inhibits Proliferation and Rho Signaling in Glioma and Neurofibromatosis type 1 Tumor Cells in an NF1-GRD Dependent Manner

Thomas J. Turbyville, Demirkan B. Gürsel, Robert G. Tuskan, Jessica C. Walrath, Claudia A. Lipschultz, Stephen J. Lockett, David F. Wiemer, John A. Beutler, Karlyne M. Reilly

Mol Cancer Ther. Author manuscript; available in PMC 2012 Jan 30.

Published in final edited form as: Mol Cancer Ther. 2010 May; 9(5): 1234–1243. Published online 2010 May 4. doi: 10.1158/1535-7163.MCT-09-0834

PMCID:: PMC3268685

Abstract Article PDF–1.7M

Select item 31277327.

Dehydrogenase GRD1 Represents a Novel Component of the Cellulase Regulon in Trichoderma reesei (Hypocrea jecorina)

André Schuster, Christian P. Kubicek, Monika Schmoll

Appl Environ Microbiol. 2011 Jul; 77(13): 4553–4563. doi: 10.1128/AEM.00513-11

PMCID:: PMC3127732

Abstract Article PDF–1.2M

Select item 15749778.

Drosophila melanogaster GRD and LCCH3 subunits form heteromultimeric GABA-gated cation channels

Günter Gisselmann, Justina Plonka, Hermann Pusch, Hanns Hatt

Br J Pharmacol. 2004 Jun; 142(3): 409–413. Published online 2004 May 17. doi: 10.1038/sj.bjp.0705818

PMCID:: PMC1574977

Abstract Article PDF–145K

Select item 2312609.

The newly identified yeast GRD genes are required for retention of late-Golgi membrane proteins.

S F Nothwehr, N J Bryant, T H Stevens

Mol Cell Biol. 1996 Jun; 16(6): 2700–2707. doi: 10.1128/mcb.16.6.2700

PMCID:: PMC231260

Summary PDF–618K

Select item 1095447910.

Structural insights into the HDAC4–MEF2A–DNA complex and its implication in long-range transcriptional regulation

Shuyan Dai, Liang Guo, Raja Dey, Ming Guo, Xiangqian Zhang, Darren Bates, Justin Cayford, Longying Jiang, Hudie Wei, Zhuchu Chen, Ye Zhang, Lin Chen, Yongheng Chen

Nucleic Acids Res. 2024 Mar 21; 52(5): 2711–2723. Published online 2024 Jan 28. doi: 10.1093/nar/gkae036

PMCID:: PMC10954479

Abstract Article PDF–3.1M

Select item 1058093811.

Glycine fermentation by C. difficile promotes virulence and spore formation, and is induced by host cathelicidin

Arshad Rizvi, Germán Vargas-Cuebas, Adrianne N. Edwards, Michael A. DiCandia, Zavier A. Carter, Cheyenne D. Lee, Marcos P. Monteiro, Shonna M. McBride

Infect Immun. 2023 Oct; 91(10): e00319-23. Published online 2023 Sep 27. doi: 10.1128/iai.00319-23

PMCID:: PMC10580938

Abstract Article PDF–2.0M

Select item 1000628012.

Genome-wide association studies reveal novel loci for resistance to groundnut rosette disease in the African core groundnut collection

Esther Achola, Peter Wasswa, Daniel Fonceka, Josh Paul Clevenger, Prasad Bajaj, Peggy Ozias-Akins, Jean-François Rami, Carl Michael Deom, David A. Hoisington, Richard Edema, Damaris Achieng Odeny, David Kalule Okello

Theor Appl Genet. 2023; 136(3): 35. Published online 2023 Mar 10. doi: 10.1007/s00122-023-04259-4

PMCID:: PMC10006280

Abstract Article PDF–10M

Select item 976956313.

Virome Analysis of Normal and Growth Retardation Disease-Affected Macrobrachiumrosenbergii

Dandan Zhou, Shanshan Liu, Guangyu Guo, Xinyi He, Chengguang Xing, Qijin Miao, Gongrui Chen, Xiaolin Chen, Hongyu Yan, Jiamin Zeng, Zhenwen Zheng, Hengwei Deng, Shaoping Weng, Jianguo He

Microbiol Spectr. 2022 Nov-Dec; 10(6): e01462-22. Published online 2022 Nov 29. doi: 10.1128/spectrum.01462-22

PMCID:: PMC9769563

Abstract Article PDF–5.4M

Select item 942606214.

A bibliometric analysis of research on genetic retinal diseases done in India

Ravichandran Kumaragurupari, Chitaranjan Mishra

Indian J Ophthalmol. 2022 Jul; 70(7): 2546–2550. Published online 2022 Jun 30. doi: 10.4103/ijo.IJO_3154_21

PMCID:: PMC9426062

Abstract Article PDF–2.1M

Select item 940837315.

CDC42-IQGAP Interactions Scrutinized: New Insights into the Binding Properties of the GAP-Related Domain

Niloufar Mosaddeghzadeh, Silke Pudewell, Farhad Bazgir, Neda S. Kazemein Jasemi, Oliver H. F. Krumbach, Lothar Gremer, Dieter Willbold, Radovan Dvorsky, Mohammad R. Ahmadian

Int J Mol Sci. 2022 Aug; 23(16): 8842. Published online 2022 Aug 9. doi: 10.3390/ijms23168842

PMCID:: PMC9408373

Abstract Article PDF–3.6M

Select item 927896616.

Long non-coding RNA FAM230B is a novel prognostic and diagnostic biomarker for lung adenocarcinoma

Yu Cao, Hong Zhang, Jianming Tang, Rui Wang

Bioengineered. 2022; 13(3): 7919–7925. Published online 2022 Mar 15. doi: 10.1080/21655979.2022.2034568

PMCID:: PMC9278966

Abstract Article PDF–1.5M

Select item 883073817.

A conserved motif in intracellular loop 1 stabilizes the outward-facing conformation of TmrAB

Cinthia R. Millan, Martina Francis, Nitesh Kumar Khandelwal, Valery F. Thompson, Tarjani M. Thaker, Thomas M. Tomasiak

J Mol Biol. Author manuscript; available in PMC 2022 Aug 6.

Published in final edited form as: J Mol Biol. 2021 Aug 6; 433(16): 166834. Published online 2021 Jan 29. doi: 10.1016/j.jmb.2021.166834

PMCID:: PMC8830738

Abstract Article PDF–2.4M

Select item 880817518.

Point mutation I634A in the glucocorticoid receptor causes embryonic lethality by reduced ligand binding

Steven Timmermans, Nicolette J.D. Verhoog, Kelly Van Looveren, Sylviane Dewaele, Tino Hochepied, Melanie Eggermont, Barbara Gilbert, Anne Boerema-de Munck, Tineke Vanderhaeghen, Joke Vanden Berghe, Natalia Garcia Gonzalez, Jolien Vandewalle, Yehudi Bloch, Mathias Provost, Savvas N. Savvides, Karolien De Bosscher, Wim Declercq, Robbert J. Rottier, Ann Louw, Claude Libert

J Biol Chem. 2022 Feb; 298(2): 101574. Published online 2022 Jan 8. doi: 10.1016/j.jbc.2022.101574

PMCID:: PMC8808175

Abstract Article PDF–3.1M

Select item 865760119.

Paradigmatic De Novo GRIN1 Variants Recapitulate Pathophysiological Mechanisms Underlying GRIN1-Related Disorder Clinical Spectrum

Ana Santos-Gómez, Federico Miguez-Cabello, Natalia Juliá-Palacios, Deyanira García-Navas, Víctor Soto-Insuga, Juan J. García-Peñas, Patricia Fuentes, Salvador Ibáñez-Micó, Laura Cuesta, Ramón Cancho, Patricia Andreo-Lillo, Gema Gutiérrez-Aguilar, Olga Alonso-Luengo, Ignacio Málaga, Antonio Hedrera-Fernández, Àngels García-Cazorla, David Soto, Mireia Olivella, Xavier Altafaj

Int J Mol Sci. 2021 Dec; 22(23): 12656. Published online 2021 Nov 23. doi: 10.3390/ijms222312656

PMCID:: PMC8657601

Abstract Article PDF–4.6M

Select item 863977720.

Structural Basis for Ligand Reception by Anaplastic Lymphoma Kinase

Tongqing Li, Steven E. Stayrook, Yuko Tsutsui, Jianan Zhang, Yueyue Wang, Hengyi Li, Andrew Proffitt, Stefan G. Krimmer, Mansoor Ahmed, Olivia Belliveau, Ian X. Walker, Krishna C. Mudumbi, Yoshihisa Suzuki, Irit Lax, Diego Alvarado, Mark A. Lemmon, Joseph Schlessinger, Daryl E. Klein

Nature. Author manuscript; available in PMC 2022 Jun 1.

Published in final edited form as: Nature. 2021 Dec; 600(7887): 148–152. Published online 2021 Nov 24. doi: 10.1038/s41586-021-04141-7

PMCID:: PMC8639777

Abstract Article PDF–4.2M

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