PMC Articles for MedGen (Select 1781689) - PMC

Select item 96354001.

Comprehensive Assessment of Anaplastic Lymphoma Kinase in Localized and Metastatic Prostate Cancer Reveals Targetable Alterations

Radhika A. Patel, Ilsa Coleman, Martine P. Roudier, Eric Q. Konnick, Brian Hanratty, Ruth Dumpit, Jared M. Lucas, Lisa S. Ang, Jin-Yih Low, Maria S. Tretiakova, Gavin Ha, John K. Lee, Lawrence D. True, Angelo M. De Marzo, Peter S. Nelson, Colm Morrissey, Colin C. Pritchard, Michael C. Haffner

Cancer Res Commun. 2022 May; 2(5): 277–285. Published online 2022 May 2. doi: 10.1158/2767-9764.CRC-21-0156

PMCID:: PMC9635400

Abstract Article PDF–5.4M

Select item 94251822.

PYK2 mediates the BRAF inhibitor (vermurafenib)-induced invadopodia formation and metastasis in melanomas

Junling Shen, Jilong Yang, Lei Sang, Rui Sun, Weiyu Bai, Chao Wang, Yan Sun, Jianwei Sun

Cancer Biol Med. 2022 Aug 15; 19(8): 1211–1223. Published online 2021 Sep 28. doi: 10.20892/j.issn.2095-3941.2020.0294

PMCID:: PMC9425182

Abstract Article PDF–1.7M

Select item 93230363.

Histological Transformation after Acquired Resistance to the Third-Generation EGFR-TKI in Patients with Advanced EGFR-Mutant Lung Adenocarcinoma

Po-Hsin Lee, Yen-Hsiang Huang, Ho Lin, Kuo-Hsuan Hsu, Kun-Chieh Chen, Jeng-Sen Tseng, Gee-Chen Chang, Tsung-Ying Yang

Medicina (Kaunas) 2022 Jul; 58(7): 908. Published online 2022 Jul 8. doi: 10.3390/medicina58070908

PMCID:: PMC9323036

Abstract Article PDF–926K

Select item 89498764.

The Prognostic Relevance of PMCA4 Expression in Melanoma: Gender Specificity and Implications for Immune Checkpoint Inhibition

Luca Hegedüs, Elisabeth Livingstone, Ágnes Bánkfalvi, Jan Viehof, Ágnes Enyedi, Ágnes Bilecz, Balázs Győrffy, Marcell Baranyi, Anna-Mária Tőkés, Jeovanis Gil, György Marko-Varga, Klaus G. Griewank, Lisa Zimmer, Renáta Váraljai, Antje Sucker, Anne Zaremba, Dirk Schadendorf, Clemens Aigner, Balázs Hegedüs

Int J Mol Sci. 2022 Mar; 23(6): 3324. Published online 2022 Mar 19. doi: 10.3390/ijms23063324

PMCID:: PMC8949876

Abstract Article PDF–3.8M

Select item 85143305.

Clinicopathological and genomic features in patients with head and neck neuroendocrine carcinoma

Akihiro Ohmoto, Yukiko Sato, Reimi Asaka, Naoki Fukuda, Xiaofei Wang, Tetsuya Urasaki, Naomi Hayashi, Yasuyoshi Sato, Kenji Nakano, Mayu Yunokawa, Makiko Ono, Junichi Tomomatsu, Takashi Toshiyasu, Hiroki Mitani, Kengo Takeuchi, Seiichi Mori, Shunji Takahashi

Mod Pathol. 2021; 34(11): 1979–1989. Published online 2021 Jul 10. doi: 10.1038/s41379-021-00869-9

PMCID:: PMC8514330

Abstract Article PDF–2.0M

Select item 82156026.

Immunoregulatory Monocyte Subset Promotes Metastasis Associated With Therapeutic Intervention for Primary Tumor

Takumi Shibuya, Asami Kamiyama, Hirotaka Sawada, Kenta Kikuchi, Mayu Maruyama, Rie Sawado, Naoki Ikeda, Kenichi Asano, Daisuke Kurotaki, Tomohiko Tamura, Atsuko Yoneda, Keisuke Imada, Takashi Satoh, Shizuo Akira, Masato Tanaka, Satoshi Yotsumoto

Front Immunol. 2021; 12: 663115. Published online 2021 Jun 7. doi: 10.3389/fimmu.2021.663115

PMCID:: PMC8215602

Abstract Article PDF–3.3M

Select item 80483837.

Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress

Anish Thomas, Nobuyuki Takahashi, Vinodh N. Rajapakse, Xiaohu Zhang, Yilun Sun, Michele Ceribelli, Kelli M. Wilson, Yang Zhang, Erin Beck, Linda Sciuto, Samantha Nichols, Brian Elenbaas, Janusz Puc, Heike Dahmen, Astrid Zimmermann, Jillian Varonin, Christopher W. Schultz, Sehyun Kim, Hirity Shimellis, Parth Desai, Carleen Klumpp-Thomas, Lu Chen, Jameson Travers, Crystal McKnight, Sam Michael, Zina Itkin, Sunmin Lee, Akira Yuno, Min-Jung Lee, Christophe E. Redon, Jessica D. Kindrick, Cody J. Peer, Jun S. Wei, Mirit I. Aladjem, William Douglas Figg, Seth M. Steinberg, Jane B. Trepel, Frank T. Zenke, Yves Pommier, Javed Khan, Craig J. Thomas

Cancer Cell. Author manuscript; available in PMC 2022 Apr 12.

Published in final edited form as: Cancer Cell. 2021 Apr 12; 39(4): 566–579.e7. doi: 10.1016/j.ccell.2021.02.014

PMCID:: PMC8048383

Abstract Article PDF–2.5M

Select item 72636288.

Clonal Evolution and Heterogeneity of Osimertinib Acquired Resistance Mechanisms in EGFR Mutant Lung Cancer

Nitin Roper, Anna-Leigh Brown, Jun S. Wei, Svetlana Pack, Christopher Trindade, Chul Kim, Olivia Restifo, Shaojian Gao, Sivasish Sindiri, Farid Mehrabadi, Rajaa El Meskini, Zoe Weaver Ohler, Tapan K. Maity, Abhilash Venugopalan, Constance M. Cultraro, Elizabeth Akoth, Emerson Padiernos, Haobin Chen, Aparna Kesarwala, DeeDee K. Smart, Naris Nilubol, Arun Rajan, Zofia Piotrowska, Liqiang Xi, Mark Raffeld, Anna R. Panchenko, Cenk Sahinalp, Stephen Hewitt, Chuong D. Hoang, Javed Khan, Udayan Guha

Cell Rep Med. 2020 Apr 21; 1(1): 100007. Published online 2020 Apr 21. doi: 10.1016/j.xcrm.2020.100007

PMCID:: PMC7263628

Abstract Article PDF–5.4M

Select item 67570209.

Clinical protein science in translational medicine targeting malignant melanoma

Jeovanis Gil, Lazaro Hiram Betancourt, Indira Pla, Aniel Sanchez, Roger Appelqvist, Tasso Miliotis, Magdalena Kuras, Henriette Oskolas, Yonghyo Kim, Zsolt Horvath, Jonatan Eriksson, Ethan Berge, Elisabeth Burestedt, Göran Jönsson, Bo Baldetorp, Christian Ingvar, Håkan Olsson, Lotta Lundgren, Peter Horvatovich, Jimmy Rodriguez Murillo, Yutaka Sugihara, Charlotte Welinder, Elisabet Wieslander, Boram Lee, Henrik Lindberg, Krzysztof Pawłowski, Ho Jeong Kwon, Viktoria Doma, Jozsef Timar, Sarolta Karpati, A. Marcell Szasz, István Balázs Németh, Toshihide Nishimura, Garry Corthals, Melinda Rezeli, Beatrice Knudsen, Johan Malm, György Marko-Varga

Cell Biol Toxicol. 2019; 35(4): 293–332. Published online 2019 Mar 21. doi: 10.1007/s10565-019-09468-6

PMCID:: PMC6757020

Abstract Article PDF–5.9M

Select item 652563310.

Delta-like protein 3 expression and therapeutic targeting in neuroendocrine prostate cancer

Loredana Puca, Katie Gavyert, Verena Sailer, Vincenza Conteduca, Etienne Dardenne, Michael Sigouros, Kumiko Isse, Megan Kearney, Aram Vosoughi, Luisa Fernandez, Heng Pan, Samaneh Motanagh, Judy Hess, Adam J. Donoghue, Andrea Sboner, Yuzhuo Wang, Ryan Dittamore, David Rickman, David M. Nanus, Scott T. Tagawa, Olivier Elemento, Juan Miguel Mosquera, Laura Saunders, Himisha Beltran

Sci Transl Med. Author manuscript; available in PMC 2019 May 18.

Published in final edited form as: Sci Transl Med. 2019 Mar 20; 11(484): eaav0891. doi: 10.1126/scitranslmed.aav0891

PMCID:: PMC6525633

Abstract Article PDF–1.3M

Select item 639292411.

Medullary thyroid carcinoma with breast metastasis: Two case reports

Kexin Meng, Wanyuan Chen, Wei Tian, Kewang Sun, Hailong Chen

Medicine (Baltimore) 2018 Nov; 97(47): e13193. Published online 2018 Nov 21. doi: 10.1097/MD.0000000000013193

PMCID:: PMC6392924

Abstract Article PDF–481K

Select item 628043312.

Isolation and characterization of two canine melanoma cell lines: new models for comparative oncology

Zacharie Segaoula, Aline Primot, Frederic Lepretre, Benoit Hedan, Emmanuel Bouchaert, Kevin Minier, Laurent Marescaux, François Serres, Sylvie Galiègue-Zouitina, Catherine André, Bruno Quesnel, Xavier Thuru, Dominique Tierny

BMC Cancer. 2018; 18: 1219. Published online 2018 Dec 4. doi: 10.1186/s12885-018-5114-y

PMCID:: PMC6280433

Abstract Article PDF–4.4M

Select item 606297613.

Emerging roles of Myc in stem cell biology and novel tumor therapies

Go J. Yoshida

J Exp Clin Cancer Res. 2018; 37: 173. Published online 2018 Jul 27. doi: 10.1186/s13046-018-0835-y

Correction in:: J Exp Clin Cancer Res. 2018; 37: 285.

PMCID:: PMC6062976

Abstract Article PDF–1.8M

Select item 530885814.

Clinical applicability and cost of a 46-gene panel for genomic analysis of solid tumours: Retrospective validation and prospective audit in the UK National Health Service

Angela Hamblin, Sarah Wordsworth, Jilles M. Fermont, Suzanne Page, Kulvinder Kaur, Carme Camps, Pamela Kaisaki, Avinash Gupta, Denis Talbot, Mark Middleton, Shirley Henderson, Anthony Cutts, Dimitrios V. Vavoulis, Nick Housby, Ian Tomlinson, Jenny C. Taylor, Anna Schuh

PLoS Med. 2017 Feb; 14(2): e1002230. Published online 2017 Feb 14. doi: 10.1371/journal.pmed.1002230

PMCID:: PMC5308858

Abstract Article PDF–2.6M

Select item 397279115.

Syntenin increases the invasiveness of small cell lung cancer cells by activating p38, AKT, focal adhesion kinase and SP1

Wook Youn Kim, Ji-young Jang, Yoon Kyung Jeon, Doo Hyun Chung, Young Goo Kim, Chul-Woo Kim

Exp Mol Med. 2014 Apr; 46(4): e90. Published online 2014 Apr 11. doi: 10.1038/emm.2014.1

PMCID:: PMC3972791

Abstract Article PDF–1.3M

Select item 542194816.

The soy-derived peptide Lunasin inhibits invasive potential of melanoma initiating cells

Chris Shidal, Jun-Ichi Inaba, Kavitha Yaddanapudi, Keith R. Davis

Oncotarget. 2017 Apr 11; 8(15): 25525–25541. Published online 2017 Mar 10. doi: 10.18632/oncotarget.16066

PMCID:: PMC5421948

Abstract Article PDF–6.3M

Select item 458210217.

Suppression of β3-integrin in mice triggers a neuropilin-1-dependent change in focal adhesion remodelling that can be targeted to block pathological angiogenesis

Tim S. Ellison, Samuel J. Atkinson, Veronica Steri, Benjamin M. Kirkup, Michael E. J. Preedy, Robert T. Johnson, Christiana Ruhrberg, Dylan R. Edwards, Jochen G. Schneider, Katherine Weilbaecher, Stephen D. Robinson

Dis Model Mech. 2015 Sep 1; 8(9): 1105–1119. doi: 10.1242/dmm.019927

PMCID:: PMC4582102

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