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Select item 102374221.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 78795092.

Expression of apoptosis repressor with caspase recruitment domain (ARC) in familial adenomatous polyposis (FAP) adenomas and its correlation with DNA mismatch repair proteins, p53, Bcl-2, COX-2 and beta-catenin

Christoph Roser, Csaba Tóth, Marcus Renner, Esther Herpel, Peter Schirmacher

Cell Commun Signal. 2021; 19: 15. Published online 2021 Feb 12. doi: 10.1186/s12964-020-00702-x

PMCID:: PMC7879509

Abstract Article PDF–1.9M

Select item 71699833.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 56306004.

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism

Giulia Antoniali, Fabrizio Serra, Lisa Lirussi, Mikiei Tanaka, Chiara D’Ambrosio, Shiheng Zhang, Slobodanka Radovic, Emiliano Dalla, Yari Ciani, Andrea Scaloni, Mengxia Li, Silvano Piazza, Gianluca Tell

Nat Commun. 2017; 8: 797. Published online 2017 Oct 6. doi: 10.1038/s41467-017-00842-8

PMCID:: PMC5630600

Abstract Article PDF–2.3M

Select item 54141565.

The role of apoptosis repressor with a CARD domain (ARC) in the therapeutic resistance of renal cell carcinoma (RCC): the crucial role of ARC in the inhibition of extrinsic and intrinsic apoptotic signalling

Csaba Toth, Sarah Funke, Vanessa Nitsche, Anna Liverts, Viktoriya Zlachevska, Marcia Gasis, Constanze Wiek, Helmut Hanenberg, Csaba Mahotka, Peter Schirmacher, Sebastian Heikaus

Cell Commun Signal. 2017; 15: 16. Published online 2017 May 2. doi: 10.1186/s12964-017-0170-5

PMCID:: PMC5414156

Abstract Article PDF–2.8M

Select item 53396836.

A myeloid tumor suppressor role for NOL3

Robert F. Stanley, Richard T. Piszczatowski, Boris Bartholdy, Kelly Mitchell, Wendy M. McKimpson, Swathi Narayanagari, Dagmar Walter, Tihomira I. Todorova, Cassandra Hirsch, Hideki Makishima, Britta Will, Christine McMahon, Kira Gritsman, Jaroslaw P. Maciejewski, Richard N. Kitsis, Ulrich Steidl

J Exp Med. 2017 Mar 6; 214(3): 753–771. doi: 10.1084/jem.20162089

PMCID:: PMC5339683

Abstract Article PDF–3.5M

Select item 49713617.

Interaction of ARC and Daxx: A Novel Endogenous Target to Preserve Motor Function and Cell Loss after Focal Brain Ischemia in Mice

Stefan Donath, Junfeng An, Sabrina Lin Lin Lee, Karen Gertz, Anna Lena Datwyler, Ulrike Harms, Susanne Müller, Tracy Deanne Farr, Martina Füchtemeier, Gisela Lättig-Tünnemann, Janet Lips, Marco Foddis, Larissa Mosch, René Bernard, Ulrike Grittner, Mustafa Balkaya, Golo Kronenberg, Ulrich Dirnagl, Matthias Endres, Christoph Harms

J Neurosci. 2016 Aug 3; 36(31): 8132–8148. doi: 10.1523/JNEUROSCI.4428-15.2016

PMCID:: PMC4971361

Abstract Article PDF–4.7M

Select item 48416078.

High-throughput analyses of hnRNP H1 dissects its multi-functional aspect

Philip J. Uren, Emad Bahrami-Samani, Patricia Rosa de Araujo, Christine Vogel, Mei Qiao, Suzanne C. Burns, Andrew D. Smith, Luiz O. F. Penalva

RNA Biol. 2016 Apr; 13(4): 400–411. Published online 2016 Jan 13. doi: 10.1080/15476286.2015.1138030

PMCID:: PMC4841607

Abstract Article PDF–1.6M

Select item 45831469.

A Critical Role for the Anti-apoptotic Protein ARC (Apoptosis Repressor with CARD) in Hypoxia-Induced Pulmonary Hypertension

Ari L Zaiman, Rachel Damico, Alan Thoms-Chesley, D Clark Files, Priya Kesari, Laura Johnston, Mara Swaim, Shehzin Mozammel, Alan C Myers, Marc Halushka, Hasim El-Haddad, Larissa A Shimoda, Chang-Fu Peng, Paul M Hassoun, Hunter C Champion, Richard N Kitsis, Michael T Crow

Circulation. Author manuscript; available in PMC 2015 Sep 25.

Published in final edited form as: Circulation. 2011 Dec 6; 124(23): 2533–2542. Published online 2011 Nov 14. doi: 10.1161/CIRCULATIONAHA.111.034512

PMCID:: PMC4583146

Abstract Article PDF–2.5M

Select item 435740010.

Apoptosis suppressor ARC modulates SMAC mimetic-induced cell death through BIRC2/MAP3K14 signalling in acute myeloid leukaemia

Po Yee Mak, Duncan H. Mak, Vivian Ruvolo, Rodrigo Jacamo, Steven M. Kornblau, Michael Andreeff, Bing Z. Carter

Br J Haematol. Author manuscript; available in PMC 2015 Nov 1.

Published in final edited form as: Br J Haematol. 2014 Nov; 167(3): 376–384. Published online 2014 Jul 31. doi: 10.1111/bjh.13054

Correction in:: Br J Haematol. 2015 Nov; 171(3): 440.

PMCID:: PMC4357400

Abstract Article PDF–1.9M

Select item 429937511.

Constant rate of p53 tetramerization in response to DNA damage controls the p53 response

Giorgio Gaglia, Galit Lahav

Mol Syst Biol. 2014 Oct 1; 10(10): 1–8. Published online 2014 Oct 24. doi: 10.15252/msb.20145168

PMCID:: PMC4299375

Abstract Article PDF–1.5M

Select item 426658812.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

Select item 400130313.

MicroRNA-185 regulates chemotherapeutic sensitivity in gastric cancer by targeting apoptosis repressor with caspase recruitment domain

Q Li, J-X Wang, Y-Q He, C Feng, X-J Zhang, J-Q Sheng, P-F Li

Cell Death Dis. 2014 Apr; 5(4): e1197. Published online 2014 Apr 24. doi: 10.1038/cddis.2014.148

PMCID:: PMC4001303

Abstract Article PDF–1.6M

Select item 395408114.

A high-throughput approach for measuring temporal changes in the interactome

Anders R. Kristensen, Joerg Gsponer, Leonard J. Foster

Nat Methods. Author manuscript; available in PMC 2014 Mar 14.

Published in final edited form as: Nat Methods. 2012 Sep; 9(9): 907–909. Published online 2012 Aug 5. doi: 10.1038/nmeth.2131

PMCID:: PMC3954081

Abstract Article PDF–632K

Select item 352603615.

The Apoptosis Inhibitor ARC Alleviates the ER Stress Response to Promote β-Cell Survival

Wendy M. McKimpson, Jeremy Weinberger, Lech Czerski, Min Zheng, Michael T. Crow, Jeffrey E. Pessin, Streamson C. Chua, Jr., Richard N. Kitsis

Diabetes. 2013 Jan; 62(1): 183–193. Published online 2012 Dec 13. doi: 10.2337/db12-0504

PMCID:: PMC3526036

Abstract Article PDF–2.5M

Select item 343119116.

Familial Cortical Myoclonus with a Mutation in NOL3

Jonathan F. Russell, Jamie L. Steckley, Giovanni Coppola, Angelika F.G. Hahn, MacKenzie A. Howard, Zachary Kornberg, Alden Huang, Seyed M. Mirsattari, Barry Merriman, Eric Klein, Murim Choi, Hsien-Yang Lee, Andrew Kirk, Carol Nelson-Williams, Gillian Gibson, Scott C. Baraban, Richard P. Lifton, Daniel H. Geschwind, Ying-Hui Fu, Louis J. Ptáček

Ann Neurol. Author manuscript; available in PMC 2013 Feb 1.

Published in final edited form as: Ann Neurol. 2012 Aug; 72(2): 175–183. doi: 10.1002/ana.23666

PMCID:: PMC3431191

Abstract Article PDF–1.1M

Select item 324574217.

Apoptosis inhibitor ARC promotes breast tumorigenesis, metastasis and chemoresistance

Christina M. Medina-Ramirez, Sumanta Goswami, Tatiana Smirnova, Daniel Bamira, Benjamin Benson, Neal Ferrick, Jeffrey Segall, Jeffrey W. Pollard, Richard N. Kitsis

Cancer Res. Author manuscript; available in PMC 2012 Dec 15.

Published in final edited form as: Cancer Res. 2011 Dec 15; 71(24): 7705–7715. Published online 2011 Oct 28. doi: 10.1158/0008-5472.CAN-11-2192

PMCID:: PMC3245742

Abstract Article PDF–2.6M

Select item 317805918.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 303507219.

Expression of ARC (apoptosis repressor with caspase recruitment domain), an antiapoptotic protein, is strongly prognostic in AML

Bing Z. Carter, Yi Hua Qiu, Nianxiang Zhang, Kevin R. Coombes, Duncan H. Mak, Deborah A. Thomas, Farhad Ravandi, Hagop M. Kantarjian, Erich Koller, Michael Andreeff, Steven M. Kornblau

Blood. 2011 Jan 20; 117(3): 780–787. Prepublished online 2010 Nov 1. doi: 10.1182/blood-2010-04-280503

PMCID:: PMC3035072

Abstract Article

Select item 303367220.

Genome-wide YFP Fluorescence Complementation Screen Identifies New Regulators for Telomere Signaling in Human Cells

Ok-Hee Lee, Hyeung Kim, Quanyuan He, Hwa Jin Baek, Dong Yang, Liuh-Yow Chen, Jiancong Liang, Heekyung Kate Chae, Amin Safari, Dan Liu, Zhou Songyang

Mol Cell Proteomics. 2011 Feb; 10(2): M110.001628. Published online 2010 Nov 11. doi: 10.1074/mcp.M110.001628

PMCID:: PMC3033672

Abstract Article PDF–1.5M

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