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Select item 101203301.

室间隔缺损与HAND2基因罕见变异的关联分析

李美琨, 逄淑超, 闫波

Zhongguo Dang Dai Er Ke Za Zhi. 2023 Apr 15; 25(4): 388–393. Chinese. doi: 10.7499/j.issn.1008-8830.2212057

PMCID:: PMC10120330

Abstract Article PDF–922K

Select item 66573592.

Hand2 Selectively Reorganizes Chromatin Accessibility to Induce Pacemaker-like Transcriptional Reprogramming

Antonio Fernandez-Perez, Adwait Amod Sathe, Minoti Bhakta, Kayla Leggett, Chao Xing, Nikhil Vilas Munshi

Cell Rep. Author manuscript; available in PMC 2019 Jul 25.

Published in final edited form as: Cell Rep. 2019 May 21; 27(8): 2354–2369.e7. doi: 10.1016/j.celrep.2019.04.077

PMCID:: PMC6657359

Abstract Article PDF–3.3M

Select item 48256663.

A HAND2 Loss-of-Function Mutation Causes Familial Ventricular Septal Defect and Pulmonary Stenosis

Yu-Min Sun, Jun Wang, Xing-Biao Qiu, Fang Yuan, Ruo-Gu Li, Ying-Jia Xu, Xin-Kai Qu, Hong-Yu Shi, Xu-Min Hou, Ri-Tai Huang, Song Xue, Yi-Qing Yang

G3 (Bethesda) 2016 Apr; 6(4): 987–992. Published online 2016 Feb 8. doi: 10.1534/g3.115.026518

PMCID:: PMC4825666

Abstract Article PDF–1.0M

Select item 102403974.

HAND2 assists MYCN enhancer invasion to regulate a noradrenergic neuroblastoma phenotype

Man Xu, Ming Sun, Xiyuan Zhang, Rosa Nguyen, Haiyan Lei, Jack F. Shern, Carol J. Thiele, Zhihui Liu

Cancer Res. Author manuscript; available in PMC 2023 Sep 2.

Published in final edited form as: Cancer Res. 2023 Mar 2; 83(5): 686–699. doi: 10.1158/0008-5472.CAN-22-2042

PMCID:: PMC10240397

Abstract Article PDF–3.4M

Select item 83651005.

Expression dynamics of HAND1/2 in in vitro human cardiomyocyte differentiation

Chikako Okubo, Megumi Narita, Azusa Inagaki, Misato Nishikawa, Akitsu Hotta, Shinya Yamanaka, Yoshinori Yoshida

Stem Cell Reports. 2021 Aug 10; 16(8): 1906–1922. Published online 2021 Jul 22. doi: 10.1016/j.stemcr.2021.06.014

PMCID:: PMC8365100

Abstract Article PDF–5.5M

Select item 82453946.

HAND2 is a novel obesity-linked adipogenic transcription factor regulated by glucocorticoid signalling

Maude Giroud, Foivos-Filippos Tsokanos, Giorgio Caratti, Stefan Kotschi, Sajjad Khani, Céline Jouffe, Elena S. Vogl, Martin Irmler, Christina Glantschnig, Manuel Gil-Lozano, Daniela Hass, Asrar Ali Khan, Marcos Rios Garcia, Frits Mattijssen, Adriano Maida, Daniel Tews, Pamela Fischer-Posovszky, Annette Feuchtinger, Kirsi A. Virtanen, Johannes Beckers, Martin Wabitsch, Henriette Uhlenhaut, Matthias Blüher, Jan Tuckermann, Marcel Scheideler, Alexander Bartelt, Stephan Herzig

Diabetologia. 2021; 64(8): 1850–1865. Published online 2021 May 20. doi: 10.1007/s00125-021-05470-y

PMCID:: PMC8245394

Abstract Article PDF–1.5M

Select item 73631307.

The transcription factor HAND2 up-regulates transcription of the IL15 gene in human endometrial stromal cells

Hiromi Murata, Susumu Tanaka, Tomoko Tsuzuki-Nakao, Takeharu Kido, Maiko Kakita-Kobayashi, Naoko Kida, Yoji Hisamatsu, Hiroaki Tsubokura, Yoshiko Hashimoto, Masaaki Kitada, Hidetaka Okada

J Biol Chem. 2020 Jul 10; 295(28): 9596–9605. Published online 2020 May 22. doi: 10.1074/jbc.RA120.012753

PMCID:: PMC7363130

Abstract Article PDF–1.7M

Select item 55520908.

Single cell qPCR reveals that additional HAND2 and microRNA-1 facilitate the early reprogramming progress of seven-factor-induced human myocytes

Emre Bektik, Adrienne Dennis, Prateek Prasanna, Anant Madabhushi, Ji-Dong Fu

PLoS One. 2017; 12(8): e0183000. Published online 2017 Aug 10. doi: 10.1371/journal.pone.0183000

PMCID:: PMC5552090

Abstract Article PDF–4.5M

Select item 54310939.

A HAND to TBX5 Explains the Link Between Thalidomide and Cardiac Diseases

Athar Khalil, Rachel Tanos, Nehmé El-Hachem, Mazen Kurban, Patrice Bouvagnet, Fadi Bitar, Georges Nemer

Sci Rep. 2017; 7: 1416. Published online 2017 May 3. doi: 10.1038/s41598-017-01641-3

PMCID:: PMC5431093

Abstract Article PDF–1.8M

Select item 314110310.

Evidence for a Conserved Function of Heart- and Neural Crest Derivatives-Expressed Transcript 2 (Hand2) in Mouse and Human Decidualization

DV Huyen, BM Bany

Reproduction. Author manuscript; available in PMC 2012 Aug 1.

Published in final edited form as: Reproduction. 2011 Aug; 142(2): 353–368. Published online 2011 Apr 28. doi: 10.1530/REP-11-0060

PMCID:: PMC3141103

Abstract Article PDF–11M

Select item 267030111.

Co-regulated expression of HAND2 and DEIN by a bidirectional promoter with asymmetrical activity in neuroblastoma

Harald Voth, André Oberthuer, Thorsten Simon, Yvonne Kahlert, Frank Berthold, Matthias Fischer

BMC Mol Biol. 2009; 10: 28. Published online 2009 Apr 6. doi: 10.1186/1471-2199-10-28

PMCID:: PMC2670301

Abstract Article PDF–492K

Select item 990035112.

NONO enhances mRNA processing of super‐enhancer‐associated GATA2 and HAND2 genes in neuroblastoma

Song Zhang, Jack AL Cooper, Yee Seng Chong, Alina Naveed, Chelsea Mayoh, Nisitha Jayatilleke, Tao Liu, Sebastian Amos, Simon Kobelke, Andrew C Marshall, Oliver Meers, Yu Suk Choi, Charles S Bond, Archa H Fox

EMBO Rep. 2023 Feb; 24(2): e54977. Published online 2022 Nov 23. doi: 10.15252/embr.202254977

PMCID:: PMC9900351

Abstract Article PDF–6.4M

Select item 304631413.

Cytokines inhibit norepinephrine transporter expression by decreasing Hand2

Michael J. Pellegrino, Diana C. Parrish, Richard E. Zigmond, Beth A. Habecker

Mol Cell Neurosci. Author manuscript; available in PMC 2012 Mar 1.

Published in final edited form as: Mol Cell Neurosci. 2011 Mar; 46(3): 671–680. Published online 2011 Jan 15. doi: 10.1016/j.mcn.2011.01.008

PMCID:: PMC3046314

Abstract Article PDF–926K

Select item 382565414.

Role of DNA Methylation and Epigenetic Silencing of HAND2 in Endometrial Cancer Development

Allison Jones, Andrew E. Teschendorff, Quanxi Li, Jane D. Hayward, Athilakshmi Kannan, Tim Mould, James West, Michal Zikan, David Cibula, Heidi Fiegl, Shih-Han Lee, Elisabeth Wik, Richard Hadwin, Rupali Arora, Charlotte Lemech, Henna Turunen, Päivi Pakarinen, Ian J. Jacobs, Helga B. Salvesen, Milan K. Bagchi, Indrani C. Bagchi, Martin Widschwendter

PLoS Med. 2013 Nov; 10(11): e1001551. Published online 2013 Nov 12. doi: 10.1371/journal.pmed.1001551

PMCID:: PMC3825654

Abstract Article PDF–1.7M

Select item 332409515.

A Phox2- and Hand2-Dependent Hand1 cis-Regulatory Element Reveals a Unique Gene Dosage Requirement for Hand2 during Sympathetic Neurogenesis

Joshua W. Vincentz, Nathan J. VanDusen, Andrew B. Fleming, Michael Rubart, Beth A. Firulli, Marthe J. Howard, Anthony B. Firulli

J Neurosci. 2012 Feb 8; 32(6): 2110–2120. doi: 10.1523/JNEUROSCI.3584-11.2012

PMCID:: PMC3324095

Abstract Article PDF–4.2M

Select item 896782516.

Hand2 delineates mesothelium progenitors and is reactivated in mesothelioma

Karin D. Prummel, Helena L. Crowell, Susan Nieuwenhuize, Eline C. Brombacher, Stephan Daetwyler, Charlotte Soneson, Jelena Kresoja-Rakic, Agnese Kocere, Manuel Ronner, Alexander Ernst, Zahra Labbaf, David E. Clouthier, Anthony B. Firulli, Héctor Sánchez-Iranzo, Sundar R. Naganathan, Rebecca O’Rourke, Erez Raz, Nadia Mercader, Alexa Burger, Emanuela Felley-Bosco, Jan Huisken, Mark D. Robinson, Christian Mosimann

Nat Commun. 2022; 13: 1677. Published online 2022 Mar 30. doi: 10.1038/s41467-022-29311-7

PMCID:: PMC8967825

Abstract Article PDF–9.8M

Select item 256132717.

The bHLH Transcription factors dHAND and eHAND Exhibit Dimerization Characteristics that Suggest Complex Regulation of Function

Beth A. Firulli, Daniel B. Hadzic, Jennifer R. McDaid, Anthony B. Firulli

J Biol Chem. Author manuscript; available in PMC 2008 Oct 6.

Published in final edited form as: J Biol Chem. 2000 Oct 27; 275(43): 33567–33573. doi: 10.1074/jbc.M005888200

PMCID:: PMC2561327

Abstract Article PDF–1.3M

Select item 285157018.

Distinct Roles of Hand2 in Initiating Polarity and Posterior Shh Expression during the Onset of Mouse Limb Bud Development

Antonella Galli, Dimitri Robay, Marco Osterwalder, Xiaozhong Bao, Jean-Denis Bénazet, Muhammad Tariq, Renato Paro, Susan Mackem, Rolf Zeller

PLoS Genet. 2010 Apr; 6(4): e1000901. Published online 2010 Apr 8. doi: 10.1371/journal.pgen.1000901

PMCID:: PMC2851570

Abstract Article PDF–2.1M

Select item 308659919.

Hand2 loss-of-function in Hand1-expressing Cells Reveals Distinct Roles In Epicardial And Coronary Vessel Development

Ralston M. Barnes, Beth A. Firulli, Nathan J. VanDusen, Yuka Morikawa, Simon J. Conway, Peter Cserjesi, Joshua W. Vincentz, Anthony B. Firulli

Circ Res. Author manuscript; available in PMC 2012 Apr 15.

Published in final edited form as: Circ Res. 2011 Apr 15; 108(8): 940–949. Published online 2011 Feb 24. doi: 10.1161/CIRCRESAHA.110.233171

PMCID:: PMC3086599

Abstract Article PDF–2.6M

Select item 655243220.

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression

Jung-Sik Kim, Xiaoyuan He, Jie Liu, Zhijun Duan, Taeyeon Kim, Julia Gerard, Brian Kim, Manoj M. Pillai, William S. Lane, William S. Noble, Bogdan Budnik, Todd Waldman

J Biol Chem. 2019 May 31; 294(22): 8760–8772. Published online 2019 Apr 22. doi: 10.1074/jbc.RA119.007832

PMCID:: PMC6552432

Abstract Article PDF–3.5M

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