PMC Links for Gene (Select 5534) - PMC

Carlos Cruchaga, John S. K. Kauwe, Kevin Mayo, Noah Spiegel, Sarah Bertelsen, Petra Nowotny, Aarti R. Shah, Richard Abraham, Paul Hollingworth, Denise Harold, Michael M. Owen, Julie Williams, Simon Lovestone, Elaine R. Peskind, Ge Li, James B. Leverenz, Douglas Galasko, The Alzheimer's Disease Neuroimaging Initiative, John C. Morris, Anne M. Fagan, David M. Holtzman, Alison M. Goate

PLoS Genet. 2010 Sep; 6(9): e1001101. Published online 2010 Sep 16. doi: 10.1371/journal.pgen.1001101

PMCID:: PMC2940763

Abstract Article PDF–305K

Select item 25818545.

Selective role of calcineurin in haematopoiesis and lymphopoiesis

Elena M Gallo, Lena Ho, Monte M Winslow, Tracy L Staton, Gerald R Crabtree

EMBO Rep. 2008 Nov; 9(11): 1141–1148. Published online 2008 Sep 26. doi: 10.1038/embor.2008.174

PMCID:: PMC2581854

Abstract Article PDF–989K

Select item 72687846.

A rare genomic duplication in 2p14 underlies autosomal dominant hearing loss DFNA58

Karina Lezirovitz, Gleiciele A Vieira-Silva, Ana C Batissoco, Débora Levy, Joao P Kitajima, Alix Trouillet, Ellen Ouyang, Navid Zebarjadi, Juliana Sampaio-Silva, Vinicius Pedroso-Campos, Larissa R Nascimento, Cindy Y Sonoda, Vinícius M Borges, Laura G Vasconcelos, Roberto M O Beck, Signe S Grasel, Daniel J Jagger, Nicolas Grillet, Ricardo F Bento, Regina C Mingroni-Netto, Jeanne Oiticica

Hum Mol Genet. 2020 Jun 3; 29(9): 1520–1536. Published online 2020 Apr 27. doi: 10.1093/hmg/ddaa075

PMCID:: PMC7268784

Abstract Article PDF–2.1M

Select item 38093447.

Variants in PPP3R1 and MAPT are associated with more rapid functional decline in Alzheimer’s disease: The Cache County Dementia Progression Study

David Peterson, Caitlin Munger, Jared Crowley, Chris Corcoran, Carlos Cruchaga, Alison M. Goate, Maria C. Norton, Robert C. Green, the Alzheimer’s Disease Neuroimaging Initiative, Ronald G. Munger, John C.S. Breitner, Kathleen A. Welsh-Bohmer, Constantine Lyketsos, JoAnn Tschanz, John S.K. Kauwe

Alzheimers Dement. Author manuscript; available in PMC 2015 May 1.

Published in final edited form as: Alzheimers Dement. 2014 May; 10(3): 366–371. Published online 2013 May 30. doi: 10.1016/j.jalz.2013.02.010

PMCID:: PMC3809344

Abstract Article PDF–497K

Select item 28112788.

Influence of promoter region variants of insulin-like growth factor pathway genes on the strength-training response of muscle phenotypes in older adults

Brian D. Hand, Matthew C. Kostek, Robert E. Ferrell, Matthew J. Delmonico, Larry W. Douglass, Stephen M. Roth, James M. Hagberg, Ben F. Hurley

J Appl Physiol. Author manuscript; available in PMC 2010 Jan 26.

Published in final edited form as: J Appl Physiol. 2007 Nov; 103(5): 1678–1687. Published online 2007 Aug 30. doi: 10.1152/japplphysiol.00420.2007

PMCID:: PMC2811278

Abstract Article PDF–653K

Select item 51569069.

Investigating the human Calcineurin Interaction Network using the πɸLxVP SLiM

Sarah R. Sheftic, Rebecca Page, Wolfgang Peti

Sci Rep. 2016; 6: 38920. Published online 2016 Dec 15. doi: 10.1038/srep38920

PMCID:: PMC5156906

Abstract Article PDF–1.4M

Select item 483570310.

Cellular uptake of exogenous calcineurin B is dependent on TLR4/MD2/CD14 complexes, and CnB is an endogenous ligand of TLR4

Jinju Yang, Nannan Qin, Hongwei Zhang, Rui Yang, Benqiong Xiang, Qun Wei

Sci Rep. 2016; 6: 24346. Published online 2016 Apr 19. doi: 10.1038/srep24346

PMCID:: PMC4835703

Abstract Article PDF–1.6M

Select item 410288711.

The LxVP and PxIxIT NFAT Motifs Bind Simultaneously to Overlapping Epitopes in Calcineurin’s Catalytic Domain CnA Distant to the Regulatory Domain CnB

Maayan Gal, Shuai Li, Rafael E. Luna, Koh Takeuchi, Gerhard Wagner

Structure. Author manuscript; available in PMC 2015 Jul 8.

Published in final edited form as: Structure. 2014 Jul 8; 22(7): 1016–1027. Published online 2014 Jun 19. doi: 10.1016/j.str.2014.05.006

PMCID:: PMC4102887

Abstract Article PDF–1.6M

Select item 358772712.

Neonatal β Cell Development in Mice and Humans Is Regulated by Calcineurin/NFAT

William R. Goodyer, Xueying Gu, Yinghua Liu, Rita Bottino, Gerald R. Crabtree, Seung K. Kim

Dev Cell. Author manuscript; available in PMC 2013 Mar 5.

Published in final edited form as: Dev Cell. 2012 Jul 17; 23(1): 21–34. doi: 10.1016/j.devcel.2012.05.014

PMCID:: PMC3587727

Abstract Article PDF–1.7M

Select item 513198813.

Exploring Regulatory Mechanisms of Atrial Myocyte Hypertrophy of Mitral Regurgitation through Gene Expression Profiling Analysis: Role of NFAT in Cardiac Hypertrophy

Tzu-Hao Chang, Mien-Cheng Chen, Jen-Ping Chang, Hsien-Da Huang, Wan-Chun Ho, Yu-Sheng Lin, Kuo-Li Pan, Yao-Kuang Huang, Wen-Hao Liu, Chia-Chen Wu

PLoS One. 2016; 11(12): e0166791. Published online 2016 Dec 1. doi: 10.1371/journal.pone.0166791

PMCID:: PMC5131988

Abstract Article PDF–4.1M

Select item 358249614.

The Molecular Mechanism of Substrate Engagement and Immunosuppressant Inhibition of Calcineurin

Simina Grigoriu, Rachel Bond, Pilar Cossio, Jennifer A. Chen, Nina Ly, Gerhard Hummer, Rebecca Page, Martha S. Cyert, Wolfgang Peti

PLoS Biol. 2013 Feb; 11(2): e1001492. Published online 2013 Feb 26. doi: 10.1371/journal.pbio.1001492

PMCID:: PMC3582496

Abstract Article PDF–1.1M

Select item 148901315.

Direct Interaction and Reciprocal Regulation between ASK1 and Calcineurin-NFAT Control Cardiomyocyte Death and Growth

Qinghang Liu, Benjamin J. Wilkins, Yong J. Lee, Hidenori Ichijo, Jeffery D. Molkentin

Mol Cell Biol. 2006 May; 26(10): 3785–3797. doi: 10.1128/MCB.26.10.3785-3797.2006

PMCID:: PMC1489013

Abstract Article PDF–727K

Select item 12970616.

Crystal structure of human calcineurin complexed with cyclosporin A and human cyclophilin

Lei Jin, Stephen C. Harrison

Proc Natl Acad Sci U S A. 2002 Oct 15; 99(21): 13522–13526. Published online 2002 Sep 30. doi: 10.1073/pnas.212504399

PMCID:: PMC129706

Abstract Article PDF–687K

Select item 12939417.

Crystal structure of calcineurin–cyclophilin–cyclosporin shows common but distinct recognition of immunophilin–drug complexes

Qing Huai, Hwa-Young Kim, Yudong Liu, Yingdong Zhao, Angelo Mondragon, Jun O. Liu, Hengming Ke

Proc Natl Acad Sci U S A. 2002 Sep 17; 99(19): 12037–12042. Published online 2002 Sep 6. doi: 10.1073/pnas.192206699

PMCID:: PMC129394

Abstract Article PDF–829K

Select item 478346618.

Cooperative autoinhibition and multi-level activation mechanisms of calcineurin

Sheng-Jie Li, Jue Wang, Lei Ma, Chang Lu, Jie Wang, Jia-Wei Wu, Zhi-Xin Wang

Cell Res. 2016 Mar; 26(3): 336–349. Published online 2016 Jan 22. doi: 10.1038/cr.2016.14

PMCID:: PMC4783466

Abstract Article PDF–5.3M

Select item 122361919.

Phosphorylation of calcipressin 1 increases its ability to inhibit calcineurin and decreases calcipressin half-life.

Lali Genescà, Anna Aubareda, Juan J Fuentes, Xavier Estivill, Susana De La Luna, Mercè Pérez-Riba

Biochem J. 2003 Sep 1; 374(Pt 2): 567–575. doi: 10.1042/BJ20030267

PMCID:: PMC1223619

Summary PDF–211K

Select item 291761720.

CIB1 is a Regulator of Pathological Cardiac Hypertrophy

Joerg Heineke, Mannix Auger-Messier, Robert N. Correll, Jian Xu, Matthew J. Benard, Weiping Yuan, Helmut Drexler, Leslie V. Parise, Jeffery D. Molkentin

Nat Med. Author manuscript; available in PMC 2011 Feb 1.

Published in final edited form as: Nat Med. 2010 Aug; 16(8): 872–879. Published online 2010 Jul 18. doi: 10.1038/nm.2181

PMCID:: PMC2917617

Abstract Article PDF–1.5M

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