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Items: 1 to 20 of 133

1.
Biphasic α2β1 Integrin Expression in Breast Cancer Metastasis to Bone
Milene N.O. Moritz, Alyssa R. Merkel, Ean G. Feldman, Heloisa S. Selistre-de-Araujo, Julie A. Rhoades (Sterling)
Int J Mol Sci. 2021 Jul; 22(13): 6906. Published online 2021 Jun 27. doi: 10.3390/ijms22136906
PMCID:
PMC8269289
ArticlePDF–3.0M
2.
Modulating Integrin αIIbβ3 Activity through Mutagenesis of Allosterically Regulated Intersubunit Contacts
Sophia K. Tan, Karen P. Fong, Nicholas F. Polizzi, Alex Sternisha, Joanna S. G. Slusky, Kyungchul Yoon, William F. DeGrado, Joel S. Bennett
Biochemistry. Author manuscript; available in PMC 2020 Aug 5.
Published in final edited form as: Biochemistry. 2019 Jul 30; 58(30): 3251–3259. Published online 2019 Jul 12. doi: 10.1021/acs.biochem.9b00430
PMCID:
PMC7405930
ArticlePDF–1.6M
3.
Human platelet antigen-3 polymorphism as a risk factor for rheumatological manifestations in hepatitis C
Natália Bronzatto Medolago, Adriana Camargo Ferrasi, Oswaldo Melo da Rocha, Maria Inês de Moura Campos Pardini, Rejane Maria Tommasini Grotto, Aline Faria Galvani, Giovanni Faria Silva
Rev Soc Bras Med Trop. 2020; 53: e20190210. Published online 2020 Jan 27. doi: 10.1590/0037-8682-0210-2019
PMCID:
PMC7083341
ArticlePDF–925K
4.
Genome-Wide Linkage Analysis and Whole-Exome Sequencing Identifies an ITGA2B Mutation in a Family with Thrombocytopenia
Rami Khoriaty, Ayse Bilge Ozel, Shweta Ramdas, Charles Ross, Karl Desch, Jordan A. Shavit, Lesley Everett, David Siemieniak, Jun Z. Li, David Ginsburg
Br J Haematol. Author manuscript; available in PMC 2020 Aug 1.
Published in final edited form as: Br J Haematol. 2019 Aug; 186(4): 574–579. Published online 2019 May 23. doi: 10.1111/bjh.15961
PMCID:
PMC6679728
ArticlePDF–895K
5.
In silico analysis of structural modifications in and around the integrin αIIb genu caused by ITGA2B variants in human platelets with emphasis on Glanzmann thrombasthenia
Xavier Pillois, Pierre Peters, Karin Segers, Alan T. Nurden
Mol Genet Genomic Med. 2018 Mar; 6(2): 249–260. Published online 2018 Jan 31. doi: 10.1002/mgg3.365
PMCID:
PMC5902390
ArticlePDF–2.7M
6.
Mechanistic Basis for the Binding of RGD- and AGDV-Peptides to the Platelet Integrin αIIbβ3
Olga Kononova, Rustem I. Litvinov, Dmitry S. Blokhin, Vladimir V. Klochkov, John W. Weisel, Joel S. Bennett, Valeri Barsegov
Biochemistry. Author manuscript; available in PMC 2018 Apr 4.
Published in final edited form as: Biochemistry. 2017 Apr 4; 56(13): 1932–1942. Published online 2017 Mar 22. doi: 10.1021/acs.biochem.6b01113
PMCID:
PMC5536102
ArticlePDF–1.4M
7.
The Interaction of Integrin αIIbβ3 with Fibrin Occurs through Multiple Binding Sites in the αIIb β-Propeller Domain
Nataly P. Podolnikova, Sergiy Yakovlev, Valentin P. Yakubenko, Xu Wang, Oleg V. Gorkun, Tatiana P. Ugarova
J Biol Chem. 2014 Jan 24; 289(4): 2371–2383. Published online 2013 Dec 12. doi: 10.1074/jbc.M113.518126
PMCID:
PMC3900980
ArticlePDF–1.3M
8.
Itga2b Regulation at the Onset of Definitive Hematopoiesis and Commitment to Differentiation
Stephanie Dumon, David S. Walton, Giacomo Volpe, Nicola Wilson, Emilie Dassé, Walter Del Pozzo, Josette-Renee Landry, Bryan Turner, Laura P. O’Neill, Berthold Göttgens, Jon Frampton
PLoS One. 2012; 7(8): e43300. Published online 2012 Aug 28. doi: 10.1371/journal.pone.0043300
PMCID:
PMC3429474
ArticlePDF–1.9M
9.
Founder effect and estimation of the age of the French Gypsy mutation associated with Glanzmann thrombasthenia in Manouche families
Mathieu Fiore, Xavier Pillois, Paquita Nurden, Alan T Nurden, Frédéric Austerlitz
Eur J Hum Genet. 2011 Sep; 19(9): 981–987. Published online 2011 Apr 13. doi: 10.1038/ejhg.2011.61
PMCID:
PMC3179361
ArticlePDF–421K
10.
Valproate, thalidomide and ethyl alcohol alter the migration of HTR-8/SVneo cells
Ujjwal K Rout
Reprod Biol Endocrinol. 2006; 4: 44. Published online 2006 Aug 21. doi: 10.1186/1477-7827-4-44
PMCID:
PMC1592099
ArticlePDF–1.0M
11.
Complete localization of the intrachain disulphide bonds and the N-glycosylation points in the alpha-subunit of human platelet glycoprotein IIb.
J J Calvete, A Henschen, J González-Rodríguez
Biochem J. 1989 Jul 15; 261(2): 561–568. doi: 10.1042/bj2610561
PMCID:
PMC1138861
SummaryPage BrowsePDF–1.1M
12.
Interchain and intrachain disulphide bonds in human platelet glycoprotein IIb. Localization of the epitopes for several monoclonal antibodies.
J J Calvete, M V Alvarez, G Rivas, C L Hew, A Henschen, J González-Rodríguez
Biochem J. 1989 Jul 15; 261(2): 551–560. doi: 10.1042/bj2610551
PMCID:
PMC1138860
SummaryPage BrowsePDF–2.6M
13.
Platelet glycoprotein IIb. Chromosomal localization and tissue expression.
P F Bray, J P Rosa, G I Johnston, D T Shiu, R G Cook, C Lau, Y W Kan, R P McEver, M A Shuman
J Clin Invest. 1987 Dec; 80(6): 1812–1817. doi: 10.1172/JCI113277
PMCID:
PMC442459
SummaryPage BrowsePDF–1.2M
14.
Platelet glycoproteins IIb and IIIa: evidence for a family of immunologically and structurally related glycoproteins in mammalian cells.
I F Charo, L A Fitzgerald, B Steiner, S C Rall, Jr, L S Bekeart, D R Phillips
Proc Natl Acad Sci U S A. 1986 Nov; 83(21): 8351–8355. doi: 10.1073/pnas.83.21.8351
PMCID:
PMC386926
SummaryPage BrowsePDF–1.2M
15.
Glanzmann thrombasthenia resulting from a single amino acid substitution between the second and third calcium-binding domains of GPIIb. Role of the GPIIb amino terminus in integrin subunit association.
D A Wilcox, C M Paddock, S Lyman, J C Gill, P J Newman
J Clin Invest. 1995 Apr; 95(4): 1553–1560. doi: 10.1172/JCI117828
PMCID:
PMC295643
SummaryPage BrowsePDF–1.9M
16.
A deletion in the gene for glycoprotein IIb associated with Glanzmann's thrombasthenia.
C D Burk, P J Newman, S Lyman, J Gill, B S Coller, M Poncz
J Clin Invest. 1991 Jan; 87(1): 270–276. doi: 10.1172/JCI114982
PMCID:
PMC295042
SummaryPage BrowsePDF–1.6M
17.
Glanzmann thrombasthenia secondary to a Gly273-->Asp mutation adjacent to the first calcium-binding domain of platelet glycoprotein IIb.
M Poncz, S Rifat, B S Coller, P J Newman, S J Shattil, T Parrella, P Fortina, J S Bennett
J Clin Invest. 1994 Jan; 93(1): 172–179. doi: 10.1172/JCI116942
PMCID:
PMC293750
SummaryPage BrowsePDF–1.8M
18.
Three-dimensional model of the human platelet integrin αIIbβ3 based on electron cryomicroscopy and x-ray crystallography
Brian D. Adair, Mark Yeager
Proc Natl Acad Sci U S A. 2002 Oct 29; 99(22): 14059–14064. Published online 2002 Oct 18. doi: 10.1073/pnas.212498199
PMCID:
PMC137836
ArticlePDF–508K
19.
Ectopic Expression of FVIII in HPCs and MSCs Derived from hiPSCs with Site-Specific Integration of ITGA2B Promoter-Driven BDDF8 Gene in Hemophilia A
Junya Zhao, Miaojin Zhou, Zujia Wang, Lingqian Wu, Zhiqing Hu, Desheng Liang
Int J Mol Sci. 2022 Jan; 23(2): 623. Published online 2022 Jan 6. doi: 10.3390/ijms23020623
PMCID:
PMC8775870
ArticlePDF–19M
20.
An alternate covalent form of platelet αIIbβ3 integrin that resides in focal adhesions and has altered function
Aster E. Pijning, Mitchell T. Blyth, Michelle L. Coote, Freda Passam, Joyce Chiu, Philip J. Hogg
Blood. 2021 Oct 14; 138(15): 1359–1372. doi: 10.1182/blood.2021012441
PMCID:
PMC8532129
Article

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