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Select item 54740121.

Knockdown of subunit 3 of the COP9 signalosome inhibits C2C12 myoblast differentiation via NF-KappaB signaling pathway

Mariam A. Ba, Jeffrey Surina, Cherie A. Singer, Maria L. Valencik

BMC Pharmacol Toxicol. 2017; 18: 47. Published online 2017 Jun 17. doi: 10.1186/s40360-017-0154-5

PMCID:: PMC5474012

Abstract Article PDF–2.2M

Select item 102627632.

The COPS3-FOXO3 positive feedback loop regulates autophagy to promote cisplatin resistance in osteosarcoma

Jianfang Niu, Taiqiang Yan, Wei Guo, Wei Wang, Tingting Ren, Yi Huang, Zhiqing Zhao, Yiyang Yu, Chenglong Chen, Qingshan Huang, Jingbing Lou, Lei Guo

Autophagy. 2023; 19(6): 1693–1710. Published online 2022 Nov 30. doi: 10.1080/15548627.2022.2150003

PMCID:: PMC10262763

Abstract Article PDF–4.9M

Select item 31850603.

Function of COP9 Signalosome in Regulation of Mouse Oocytes Meiosis by Regulating MPF Activity and Securing Degradation

Eunju Kim, Se-Jin Yoon, Eun-Young Kim, Yunna Kim, Hyun-Seo Lee, Kyeoung-Hwa Kim, Kyung-Ah Lee

PLoS One. 2011; 6(10): e25870. Published online 2011 Oct 3. doi: 10.1371/journal.pone.0025870

PMCID:: PMC3185060

Abstract Article PDF–3.3M

Select item 1939334.

COP9 Signalosome Subunit 3 Is Essential for Maintenance of Cell Proliferation in the Mouse Embryonic Epiblast

Jiong Yan, Katherina Walz, Hisashi Nakamura, Sandra Carattini-Rivera, Qi Zhao, Hannes Vogel, Ning Wei, Monica J. Justice, Allan Bradley, James R. Lupski

Mol Cell Biol. 2003 Oct; 23(19): 6798–6808. doi: 10.1128/MCB.23.19.6798-6808.2003

PMCID:: PMC193933

Abstract Article PDF–1.0M

Select item 63285645.

The CSN3 subunit of the COP9 signalosome interacts with the HD region of Sos1 regulating stability of this GEF protein

Natasha Zarich, Begoña Anta, Alberto Fernández-Medarde, Alicia Ballester, María Pilar de Lucas, Ana Belén Cámara, Berta Anta, José Luís Oliva, José M. Rojas-Cabañeros, Eugenio Santos

Oncogenesis. 2019 Jan; 8(1): 2. Published online 2019 Jan 4. doi: 10.1038/s41389-018-0111-1

PMCID:: PMC6328564

Abstract Article PDF–1.3M

Select item 29907076.

Phenotypic Consequences of Copy Number Variation: Insights from Smith-Magenis and Potocki-Lupski Syndrome Mouse Models

Guénola Ricard, Jessica Molina, Jacqueline Chrast, Wenli Gu, Nele Gheldof, Sylvain Pradervand, Frédéric Schütz, Juan I. Young, James R. Lupski, Alexandre Reymond, Katherina Walz

PLoS Biol. 2010 Nov; 8(11): e1000543. Published online 2010 Nov 23. doi: 10.1371/journal.pbio.1000543

PMCID:: PMC2990707

Abstract Article PDF–792K

Select item 80806317.

IP₆-assisted CSN-COP1 competition regulates a CRL4-ETV5 proteolytic checkpoint to safeguard glucose-induced insulin secretion

Hong Lin, Yuan Yan, Yifan Luo, Wing Yan So, Xiayun Wei, Xiaozhe Zhang, Xiaoli Yang, Jun Zhang, Yang Su, Xiuyan Yang, Bobo Zhang, Kangjun Zhang, Nan Jiang, Billy Kwok Chong Chow, Weiping Han, Fengchao Wang, Feng Rao

Nat Commun. 2021; 12: 2461. Published online 2021 Apr 28. doi: 10.1038/s41467-021-22941-3

PMCID:: PMC8080631

Abstract Article PDF–3.1M

Select item 41573188.

Loss of Jab1 in Osteochondral Progenitor Cells Severely Impairs Embryonic Limb Development in Mice

Lindsay A. Bashur, Dongxing Chen, Zhijun Chen, Bojian Liang, Ruggero Pardi, Shunichi Murakami, Guang Zhou

J Cell Physiol. Author manuscript; available in PMC 2015 Nov 1.

Published in final edited form as: J Cell Physiol. 2014 Nov; 229(11): 1607–1617. doi: 10.1002/jcp.24602

PMCID:: PMC4157318

Abstract Article PDF–3.3M

Select item 18211109.

Penetrance of Craniofacial Anomalies in Mouse Models of Smith-Magenis Syndrome Is Modified by Genomic Sequence Surrounding Rai1: Not All Null Alleles Are Alike

Jiong Yan, Weimin Bi, James R. Lupski

Am J Hum Genet. 2007 Mar; 80(3): 518–525. Published online 2007 Jan 18. doi: 10.1086/512043

PMCID:: PMC1821110

Abstract Article PDF–1.5M

Select item 501612210.

Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4^CRBN and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Functions and Neurodegeneration

Dolores Del Prete, Richard C. Rice, Anjali M. Rajadhyaksha, Luciano D'Adamio

J Biol Chem. 2016 Aug 12; 291(33): 17209–17227. Published online 2016 Jun 20. doi: 10.1074/jbc.M116.733626

PMCID:: PMC5016122

Abstract Article PDF–1.8M

Select item 468613611.

Systematic Identification of Factors for Provirus Silencing in Embryonic Stem Cells

Bin Xia Yang, Chadi A. EL Farran, Hong Chao Guo, Tao Yu, Hai Tong Fang, Hao Fei Wang, Sharon Schlesinger, Yu Fen Samantha Seah, Germaine Yen Lin Goh, Suat Peng Neo, Yinghui Li, Matthew C. Lorincz, Vinay Tergaonkar, Tit-Meng Lim, Lingyi Chen, Jayantha Gunaratne, James J. Collins, Stephen P. Goff, George Q. Daley, Hu Li, Frederic A. Bard, Yuin-Han Loh

Cell. Author manuscript; available in PMC 2015 Dec 21.

Published in final edited form as: Cell. 2015 Sep 24; 163(1): 230–245. Published online 2015 Sep 10. doi: 10.1016/j.cell.2015.08.037

PMCID:: PMC4686136

Abstract Article PDF–1.2M

Select item 534152012.

The antiobesity factor WDTC1 suppresses adipogenesis via the CRL4^WDTC¹ E3 ligase

Beezly S Groh, Feng Yan, Matthew D Smith, Yanbao Yu, Xian Chen, Yue Xiong

EMBO Rep. 2016 May; 17(5): 638–647. Published online 2016 Apr 9. doi: 10.15252/embr.201540500

PMCID:: PMC5341520

Abstract Article PDF–1.1M

Select item 435840313.

Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt

Jernej Murn, Kathi Zarnack, Yawei J. Yang, Omer Durak, Elisabeth A. Murphy, Sihem Cheloufi, Dilenny M. Gonzalez, Marianna Teplova, Tomaž Curk, Johannes Zuber, Dinshaw J. Patel, Jernej Ule, Nicholas M. Luscombe, Li-Huei Tsai, Christopher A. Walsh, Yang Shi

Genes Dev. 2015 Mar 1; 29(5): 501–512. doi: 10.1101/gad.258483.115

PMCID:: PMC4358403

Abstract Article PDF–1.4M

Select item 343984514.

A Genome-Wide Screen to Identify Transcription Factors Expressed in Pelvic Ganglia of the Lower Urinary Tract

Carrie B. Wiese, Sara Ireland, Nicole L. Fleming, Jing Yu, M. Todd Valerius, Kylie Georgas, Han Sheng Chiu, Jane Brennan, Jane Armstrong, Melissa H. Little, Andrew P. McMahon, E. Michelle Southard-Smith

Front Neurosci. 2012; 6: 130. Published online 2012 Sep 12. doi: 10.3389/fnins.2012.00130

PMCID:: PMC3439845

Abstract Article PDF–1.4M

Select item 741599115.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 407349416.

The Central Role of EED in the Orchestration of Polycomb Group Complexes

Qi Cao, Xiaoju Wang, Meng Zhao, Rendong Yang, Rohit Malik, Yuanyuan Qiao, Anton Poliakov, Anastasia K. Yocum, Yong Li, Wei Chen, Xuhong Cao, Xia Jiang, Arun Dahiya, Clair Harris, Felix Y. Feng, Sundeep Kalantry, Zhaohui S. Qin, Saravana M. Dhanasekaran, Arul M. Chinnaiyan

Nat Commun. Author manuscript; available in PMC 2014 Jul 24.

Published in final edited form as: Nat Commun. 2014; 5: 3127. doi: 10.1038/ncomms4127

PMCID:: PMC4073494

Abstract Article PDF–2.1M

Select item 16551117.

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells

Doug Stryke, Michiko Kawamoto, Conrad C. Huang, Susan J. Johns, Leslie A. King, Courtney A. Harper, Elaine C. Meng, Roy E. Lee, Alice Yee, Larry L'Italien, Pao-Tien Chuang, Stephen G. Young, William C. Skarnes, Patricia C. Babbitt, Thomas E. Ferrin

Nucleic Acids Res. 2003 Jan 1; 31(1): 278–281. doi: 10.1093/nar/gkg064

PMCID:: PMC165511

Abstract Article PDF–217K

Select item 793877018.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 1683319.

Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray

Tetsuya S. Tanaka, Saied A. Jaradat, Meng K. Lim, George J. Kargul, Xiaohong Wang, Marija J. Grahovac, Serafino Pantano, Yuri Sano, Yulan Piao, Ramaiah Nagaraja, Hirofumi Doi, William H. Wood, III, Kevin G. Becker, Minoru S. H. Ko

Proc Natl Acad Sci U S A. 2000 Aug 1; 97(16): 9127–9132. doi: 10.1073/pnas.97.16.9127

PMCID:: PMC16833

Abstract Article PDF–847K

Select item 357241020.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

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