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Select item 103449621.

Inhibition of AXL receptor tyrosine kinase enhances brown adipose tissue functionality in mice

Vissarion Efthymiou, Lianggong Ding, Miroslav Balaz, Wenfei Sun, Lucia Balazova, Leon G. Straub, Hua Dong, Eric Simon, Adhideb Ghosh, Aliki Perdikari, Svenja Keller, Umesh Ghoshdastider, Carla Horvath, Caroline Moser, Bradford Hamilton, Heike Neubauer, Christian Wolfrum

Nat Commun. 2023; 14: 4162. Published online 2023 Jul 13. doi: 10.1038/s41467-023-39715-8

PMCID:: PMC10344962

Abstract Article PDF–4.6M

Select item 102008752.

Axl promotes intracranial aneurysm rupture by regulating macrophage polarization toward M1 via STAT1/HIF-1α

Yongquan Han, Gaozhi Li, Zeyu Zhang, Xiaohua Zhang, Bing Zhao, Hua Yang

Front Immunol. 2023; 14: 1158758. Published online 2023 May 8. doi: 10.3389/fimmu.2023.1158758

PMCID:: PMC10200875

Abstract Article PDF–14M

Select item 100679633.

Axl alleviates DSS-induced colitis by preventing dysbiosis of gut microbiota

Su-Min Yee, Harim Choi, Jeong-Eun Seon, Yu-Jin Ban, Min-Jae Kim, Jae-Eun Seo, Ja Hun Seo, Sehyeon Kim, Seo Hee Moon, Chul-Ho Yun, Hyang Burm Lee, Hyung-Sik Kang

Sci Rep. 2023; 13: 5371. Published online 2023 Apr 1. doi: 10.1038/s41598-023-32527-2

PMCID:: PMC10067963

Abstract Article PDF–5.4M

Select item 96027154.

Role of Axl in target organ inflammation and damage due to hypertensive aortic remodeling

Wei Chen, Justin P. Van Beusecum, Liang Xiao, David M. Patrick, Mingfang Ao, Shilin Zhao, Marcos G. Lopez, Frederic T. Billings, 4th, Cristina Cavinato, Alexander W. Caulk, Jay D. Humphrey, David G. Harrison

Am J Physiol Heart Circ Physiol. 2022 Nov 1; 323(5): H917–H933. Published online 2022 Sep 9. doi: 10.1152/ajpheart.00253.2022

PMCID:: PMC9602715

Abstract Article

Select item 92130825.

Activated AXL Protects Against Hepatic Ischemia-reperfusion Injury by Upregulating SOCS-1 Expression

Zhen Wang, Deng Liu, Qi Yan, Fang Liu, Mengting Zhan, Shunli Qi, Qi Fang, Lei Yao, Weizhi Wang, Ruixin Zhang, Jian Du, Lijian Chen

Transplantation. 2022 Jul; 106(7): 1351–1364. Published online 2022 May 11. doi: 10.1097/TP.0000000000004156

PMCID:: PMC9213082

Abstract Article PDF–7.2M

Select item 82649936.

AXL kinase-mediated astrocytic phagocytosis modulates outcomes of traumatic brain injury

Hang Zhou, Libin Hu, Jianru Li, Wu Ruan, Yang Cao, Jianfeng Zhuang, Hangzhe Xu, Yucong Peng, Zhongyuan Zhang, Chaoran Xu, Qian Yu, Yin Li, Zhangqi Dou, Junwen Hu, Xinyan Wu, Xiaobo Yu, Chi Gu, Shenglong Cao, Feng Yan, Gao Chen

J Neuroinflammation. 2021; 18: 154. Published online 2021 Jul 7. doi: 10.1186/s12974-021-02201-3

PMCID:: PMC8264993

Abstract Article PDF–7.4M

Select item 75787597.

AXL Is a Driver of Stemness in Normal Mammary Gland and Breast Cancer

Agnete S.T. Engelsen, Katarzyna Wnuk-Lipinska, Sebastien Bougnaud, Fanny A. Pelissier Vatter, Crina Tiron, René Villadsen, Masaru Miyano, Maria L. Lotsberg, Noëlly Madeleine, Pouda Panahandeh, Sushil Dhakal, Tuan Zea Tan, Stacey D’mello Peters, Sturla Grøndal, Sura M. Aziz, Silje Nord, Lars Herfindal, Martha R. Stampfer, Therese Sørlie, Rolf A. Brekken, Oddbjørn Straume, Nils Halberg, Gro Gausdal, Jean Paul Thiery, Lars A. Akslen, Ole W. Petersen, Mark A. LaBarge, James B. Lorens

iScience. 2020 Nov 20; 23(11): 101649. Published online 2020 Oct 7. doi: 10.1016/j.isci.2020.101649

PMCID:: PMC7578759

Abstract Article PDF–13M

Select item 74318078.

Axl Deficiency Promotes the Neuroinvasion of Japanese Encephalitis Virus by Enhancing IL-1α Production from Pyroptotic Macrophages

Zhao-Yang Wang, Zi-Da Zhen, Dong-Ying Fan, Cheng-Feng Qin, Dai-Shu Han, Hong-Ning Zhou, Pei-Gang Wang, Jing An

J Virol. 2020 Sep; 94(17): e00602-20. Prepublished online 2020 Jul 1. Published online 2020 Aug 17. doi: 10.1128/JVI.00602-20

PMCID:: PMC7431807

Abstract Article PDF–8.4M

Select item 61089479.

Targeted inhibition of Axl receptor tyrosine kinase ameliorates anti-GBM-induced lupus-like nephritis

Yuxuan Zhen, Iris J. Lee, Fred D. Finkelman, Wen-Hai Shao

J Autoimmun. Author manuscript; available in PMC 2019 Sep 1.

Published in final edited form as: J Autoimmun. 2018 Sep; 93: 37–44. Published online 2018 Jun 9. doi: 10.1016/j.jaut.2018.06.001

PMCID:: PMC6108947

Abstract Article PDF–1.2M

Select item 565678410.

Axl is not an indispensable factor for Zika virus infection in mice

Zhao-Yang Wang, Zai Wang, Zi-Da Zhen, Kai-Hao Feng, Jing Guo, Na Gao, Dong-Ying Fan, Dai-Shu Han, Pei-Gang Wang, Jing An

J Gen Virol. 2017 Aug; 98(8): 2061–2068. Published online 2017 Aug 8. doi: 10.1099/jgv.0.000886

PMCID:: PMC5656784

Abstract Article PDF–6.6M

Select item 537892211.

AXL is not essential for Zika virus infection in the mouse brain

Feng Li, Pei-Rong Wang, Lin-Bing Qu, Chang-Hua Yi, Fu-Chun Zhang, Xiao-Ping Tang, Li-Guo Zhang, Ling Chen

Emerg Microbes Infect. 2017 Mar; 6(3): e16. Published online 2017 Mar 29. doi: 10.1038/emi.2017.10

PMCID:: PMC5378922

Article PDF–398K

Select item 519643812.

Reprogramming the immunological microenvironment through radiation and targeting Axl

Todd A. Aguilera, Marjan Rafat, Laura Castellini, Hussein Shehade, Mihalis S. Kariolis, Angela Bik-Yu Hui, Henning Stehr, Rie von Eyben, Dadi Jiang, Lesley G. Ellies, Albert C. Koong, Maximilian Diehn, Erinn B. Rankin, Edward E. Graves, Amato J. Giaccia

Nat Commun. 2016; 7: 13898. Published online 2016 Dec 23. doi: 10.1038/ncomms13898

PMCID:: PMC5196438

Abstract Article PDF–1.7M

Select item 492499613.

AXL receptor tyrosine kinase is required for T cell priming and antiviral immunity

Edward T Schmid, Iris K Pang, Eugenio A Carrera Silva, Lidia Bosurgi, Jonathan J Miner, Michael S Diamond, Akiko Iwasaki, Carla V Rothlin

eLife. 2016; 5: e12414. Published online 2016 Jun 28. doi: 10.7554/eLife.12414

PMCID:: PMC4924996

Abstract Article PDF–2.4M

Select item 450962314.

Axl receptor blockade ameliorates pulmonary pathology resulting from primary viral infection and viral exacerbation of asthma

Takehiko Shibata, David M. Habiel, Ana L. Coelho, Steven L. Kunkel, Nicholas W. Lukacs, Cory M. Hogaboam

J Immunol. Author manuscript; available in PMC 2015 Jul 21.

Published in final edited form as: J Immunol. 2014 Apr 15; 192(8): 3569–3581. Published online 2014 Mar 21. doi: 10.4049/jimmunol.1302766

PMCID:: PMC4509623

Abstract Article PDF–3.5M

Select item 443029815.

The Axl receptor tyrosine kinase is a discriminator of macrophage function in the inflamed lung

T Fujimori, A M Grabiec, M Kaur, T J Bell, N Fujino, P C Cook, F R Svedberg, A S MacDonald, R A Maciewicz, D Singh, T Hussell

Mucosal Immunol. 2015; 8(5): 1021–1030. Published online 2015 Jan 21. doi: 10.1038/mi.2014.129

PMCID:: PMC4430298

Abstract Article PDF–2.4M

Select item 382252316.

ROLE OF AXL IN EARLY KIDNEY INFLAMMATION AND PROGRESSION OF SALT-DEPENDENT HYPERTENSION

Sri N. Batchu, Angie Hughson, Janice Gerloff, Deborah J. Fowell, Vyacheslav A. Korshunov

Hypertension. Author manuscript; available in PMC 2014 Aug 1.

Published in final edited form as: Hypertension. 2013 Aug; 62(2): 10.1161/HYPERTENSIONAHA.113.01382. Published online 2013 Jun 17. doi: 10.1161/HYPERTENSIONAHA.113.01382

PMCID:: PMC3822523

Abstract Article PDF–2.1M

Select item 362419317.

Is the TAM Receptor Axl a Receptor for Lymphocytic Choriomeningitis Virus?

Brian M. Sullivan, Megan J. Welch, Greg Lemke, Michael B. A. Oldstone

J Virol. 2013 Apr; 87(7): 4071–4074. doi: 10.1128/JVI.03268-12

PMCID:: PMC3624193

Abstract Article PDF–843K

Select item 347110518.

Axl glycosylation mediates tumor cell proliferation, invasion and lymphatic metastasis in murine hepatocellular carcinoma

Ji Li, Li Jia, Zhen-Hai Ma, Qiu-Hong Ma, Xiao-Hong Yang, Yong-Fu Zhao

World J Gastroenterol. 2012 Oct 14; 18(38): 5369–5376. Published online 2012 Oct 14. doi: 10.3748/wjg.v18.i38.5369

PMCID:: PMC3471105

Abstract Article PDF–1014K

Select item 312161519.

Loss of the receptor tyrosine kinase Axl leads to enhanced inflammation in the CNS and delayed removal of myelin debris during Experimental Autoimmune Encephalomyelitis

Jason G Weinger, Celia F Brosnan, Olivier Loudig, Michael F Goldberg, Fernando Macian, Heather A Arnett, Anne L Prieto, Vladislav Tsiperson, Bridget Shafit-Zagardo

J Neuroinflammation. 2011; 8: 49. Published online 2011 May 15. doi: 10.1186/1742-2094-8-49

PMCID:: PMC3121615

Abstract Article PDF–11M

Select item 1110645720.

Differential regulation of lung homeostasis and silicosis by the TAM receptors MerTk and Axl

Kamila Guimarães-Pinto, Monique Leandro, Antonia Corrêa, Ester P. Maia, Leticia Rodrigues, André Luiz Amorim da Costa, Jesuino Rafael Machado Ferreira, Estefannia Claudio-Etienne, Ulrich Siebenlist, Jianping He, Thaís da Silva Rigoni, Tatiana Paula Teixeira Ferreira, Yago Amigo Pinho Jannini-Sa, Herbert Leonel Matos-Guedes, Ana Caroline Costa-da-Silva, Marcela Freitas Lopes, Patricia Machado Rodrigues Silva, Brian Lee Kelsall, Alessandra Almeida Filardy

Front Immunol. 2024; 15: 1380628. Published online 2024 May 7. doi: 10.3389/fimmu.2024.1380628

PMCID:: PMC11106457

Abstract Article PDF–4.6M

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PMC Links for Gene (Select 26362) (132)
PMC
Homo sapiens cDNA FLJ30866 fis, clone FEBRA2004110, highly similar to PHOSPHOLIP...
Homo sapiens cDNA FLJ30866 fis, clone FEBRA2004110, highly similar to PHOSPHOLIPASE ADRAB-B PRECURSOR (EC 3.1.-.-)
gi|16550150|dbj|AK055428.1|

Nucleotide
PREDICTED: Mus musculus AXL receptor tyrosine kinase (Axl), transcript variant X...
PREDICTED: Mus musculus AXL receptor tyrosine kinase (Axl), transcript variant X1, mRNA
gi|1907181496|ref|XM_006539989.5|

Nucleotide
Gene expression (mRNA-seq) in the developing chicken retinal pigment epithelium
Gene expression (mRNA-seq) in the developing chicken retinal pigment epithelium
Gene expression (mRNA-seq) in the developing chicken retinal pigment epithelium

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