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Select item 104765641.

Disordered testosterone transport in mice lacking the ganglioside GM2/GD2 synthase gene

Koichi Furukawa, Kogo Takamiya, Yuhsuke Ohmi, Robiul H. Bhuiyan, Orie Tajima, Keiko Furukawa

FEBS Open Bio. 2023 Sep; 13(9): 1615–1624. Published online 2023 Apr 6. doi: 10.1002/2211-5463.13603

PMCID:: PMC10476564

Abstract Article PDF–2.0M

Select item 94094522.

Attenuation of Bone Formation through a Decrease in Osteoblasts in Mutant Mice Lacking the GM2/GD2 Synthase Gene

Eri Sasaki, Kazunori Hamamura, Yoshitaka Mishima, Koichi Furukawa, Mayu Nagao, Hanami Kato, Kosuke Hamajima, Takuma Sato, Ken Miyazawa, Shigemi Goto, Akifumi Togari

Int J Mol Sci. 2022 Aug; 23(16): 9044. Published online 2022 Aug 12. doi: 10.3390/ijms23169044

PMCID:: PMC9409452

Abstract Article PDF–4.5M

Select item 67578593.

Complex Gangliosides at the Neuromuscular Junction Are Membrane Receptors for Autoantibodies and Botulinum Neurotoxin But Redundant for Normal Synaptic Function

Roland W. M. Bullens, Graham M. O'Hanlon, Eric Wagner, Peter C. Molenaar, Keiko Furukawa, Koichi Furukawa, Jaap J. Plomp, Hugh J. Willison

J Neurosci. 2002 Aug 15; 22(16): 6876–6884. doi: 10.1523/JNEUROSCI.22-16-06876.2002

PMCID:: PMC6757859

Abstract Article PDF–263K

Select item 67258744.

Enhanced Susceptibility to Kainate-Induced Seizures, Neuronal Apoptosis, and Death in Mice Lacking Gangliotetraose Gangliosides: Protection with LIGA 20, a Membrane-Permeant Analog of GM1

Gusheng Wu, Zi-Hua Lu, Jianfeng Wang, Yvette Wang, Xin Xie, Markus F. Meyenhofer, Robert W. Ledeen

J Neurosci. 2005 Nov 23; 25(47): 11014–11022. doi: 10.1523/JNEUROSCI.3635-05.2005

PMCID:: PMC6725874

Abstract Article PDF–624K

Select item 66124485.

FTY720 Improves Behavior, Increases Brain Derived Neurotrophic Factor and Reduces α-Synuclein Pathology in Parkinsonian GM2+/− Mice

Guadalupe Vidal-Martinez, Katherine Najera, Julie D. Miranda, Carolina Gil-Tommee, Barbara Yang, Javier Vargas-Medrano, Valeria Diaz-Pacheco, Ruth G. Perez

Neuroscience. Author manuscript; available in PMC 2020 Jul 15.

Published in final edited form as: Neuroscience. 2019 Jul 15; 411: 1–10. Published online 2019 May 23. doi: 10.1016/j.neuroscience.2019.05.029

PMCID:: PMC6612448

Abstract Article PDF–1.1M

Select item 63192676.

Parkinsonian GM2 Synthase Mice Lacking Mature Gangliosides Develop Urinary Dysfunction and Neurogenic Bladder

Carolina Gil-Tommee, Guadalupe Vidal-Martínez, C. Annette Reyes, Javier Vargas-Medrano, Gloria V. Herrera, Silver M. Martin, Stephanie A. Chaparro, Ruth G. Perez

Exp Neurol. Author manuscript; available in PMC 2019 Jan 4.

Published in final edited form as: Exp Neurol. 2019 Jan; 311: 265–273. Published online 2018 Oct 25. doi: 10.1016/j.expneurol.2018.10.014

PMCID:: PMC6319267

Abstract Article PDF–1.5M

Select item 45139857.

Ganglioside accumulation in activated glia in the developing brain: comparison between WT and GalNAcT KO mice

Mariko Saito, Gusheng Wu, Maria Hui, Kurt Masiello, Kostantin Dobrenis, Robert W. Ledeen, Mitsuo Saito

J Lipid Res. 2015 Aug; 56(8): 1434–1448. doi: 10.1194/jlr.M056580

PMCID:: PMC4513985

Abstract Article PDF–3.2M

Select item 227998.

Complex gangliosides are essential in spermatogenesis of mice: Possible roles in the transport of testosterone

Kogo Takamiya, Akihito Yamamoto, Keiko Furukawa, Jinmin Zhao, Satoshi Fukumoto, Shuji Yamashiro, Masahiko Okada, Masashi Haraguchi, Masashi Shin, Masao Kishikawa, Hiroshi Shiku, Shinichi Aizawa, Koichi Furukawa

Proc Natl Acad Sci U S A. 1998 Oct 13; 95(21): 12147–12152. doi: 10.1073/pnas.95.21.12147

PMCID:: PMC22799

Abstract Article PDF–759K

Select item 221209.

Mice lacking complex gangliosides develop Wallerian degeneration and myelination defects

Kazim A. Sheikh, Ji Sun, Yujing Liu, Hiromichi Kawai, Thomas O. Crawford, Richard L. Proia, John W. Griffin, Ronald L. Schnaar

Proc Natl Acad Sci U S A. 1999 Jun 22; 96(13): 7532–7537. doi: 10.1073/pnas.96.13.7532

PMCID:: PMC22120

Abstract Article PDF–560K

Select item 1458610.

Cerebellar neurons lacking complex gangliosides degenerate in the presence of depolarizing levels of potassium

Gusheng Wu, Xin Xie, Zi-Hua Lu, Robert W. Ledeen

Proc Natl Acad Sci U S A. 2001 Jan 2; 98(1): 307–312. Published online 2000 Dec 26. doi: 10.1073/pnas.011523698

PMCID:: PMC14586

Abstract Article PDF–301K

Select item 961532211.

Ganglioside lipidomics of CNS myelination using direct infusion shotgun mass spectrometry

Martina Arends, Melanie Weber, Cyrus Papan, Markus Damm, Michal A. Surma, Christopher Spiegel, Minou Djannatian, Shengrong Li, Lisa Connell, Ludger Johannes, Martina Schifferer, Christian Klose, Mikael Simons

iScience. 2022 Nov 18; 25(11): 105323. Published online 2022 Oct 10. doi: 10.1016/j.isci.2022.105323

PMCID:: PMC9615322

Abstract Article PDF–2.9M

Select item 682400712.

KIF11 as a Potential Marker of Spermatogenesis Within Mouse Seminiferous Tubule Cross-sections

Miki Hara-Yokoyama, Hidetake Kurihara, Shozo Ichinose, Hironori Matsuda, Shizuko Ichinose, Masaru Kurosawa, Norihiro Tada, Chihiro Iwahara, Kazue Terasawa, Katarzyna A. Podyma-Inoue, Koichi Furukawa, Kazuhisa Iwabuchi

J Histochem Cytochem. 2019 Nov; 67(11): 813–824. Published online 2019 Aug 19. doi: 10.1369/0022155419871027

PMCID:: PMC6824007

Abstract Article PDF–2.7M

Select item 672593913.

Overexpression of GD1a Ganglioside Sensitizes Motor Nerve Terminals to Anti-GD1a Antibody-Mediated Injury in a Model of Acute Motor Axonal Neuropathy

John A. Goodfellow, Tyrone Bowes, Kazim Sheikh, Masaaki Odaka, Susan K. Halstead, Peter D. Humphreys, Eric R. Wagner, Nobuhiro Yuki, Koichi Furukawa, Keiko Furukawa, Jaap J. Plomp, Hugh J. Willison

J Neurosci. 2005 Feb 16; 25(7): 1620–1628. doi: 10.1523/JNEUROSCI.4279-04.2005

PMCID:: PMC6725939

Abstract Article PDF–643K

Select item 460883614.

Ganglioside and Non-ganglioside Mediated Host Responses to the Mouse Polyomavirus

John You, Samantha D. O’Hara, Palanivel Velupillai, Sherry Castle, Steven Levery, Robert L. Garcea, Thomas Benjamin

PLoS Pathog. 2015 Oct; 11(10): e1005175. Published online 2015 Oct 16. doi: 10.1371/journal.ppat.1005175

PMCID:: PMC4608836

Abstract Article PDF–6.4M

Select item 460879915.

Structural and Functional Analysis of Murine Polyomavirus Capsid Proteins Establish the Determinants of Ligand Recognition and Pathogenicity

Michael H. C. Buch, A. Manuel Liaci, Samantha D. O’Hara, Robert L. Garcea, Ursula Neu, Thilo Stehle

PLoS Pathog. 2015 Oct; 11(10): e1005104. Published online 2015 Oct 16. doi: 10.1371/journal.ppat.1005104

PMCID:: PMC4608799

Abstract Article PDF–7.2M

Select item 417281116.

Ganglioside Regulation of AMPA Receptor Trafficking

Jillian Prendergast, George K.E. Umanah, Seung-Wan Yoo, Olof Lagerlöf, Mary G. Motari, Robert N. Cole, Richard L. Huganir, Ted M. Dawson, Valina L. Dawson, Ronald L. Schnaar

J Neurosci. 2014 Sep 24; 34(39): 13246–13258. doi: 10.1523/JNEUROSCI.1149-14.2014

PMCID:: PMC4172811

Abstract Article PDF–4.5M

Select item 389196517.

Neuronal Expression of GalNAc Transferase Is Sufficient to Prevent the Age-Related Neurodegenerative Phenotype of Complex Ganglioside-Deficient Mice

Denggao Yao, Rhona McGonigal, Jennifer A. Barrie, Joanna Cappell, Madeleine E. Cunningham, Gavin R. Meehan, Simon N. Fewou, Julia M. Edgar, Edward Rowan, Yuhsuke Ohmi, Keiko Furukawa, Koichi Furukawa, Peter J. Brophy, Hugh J. Willison

J Neurosci. 2014 Jan 15; 34(3): 880–891. doi: 10.1523/JNEUROSCI.3996-13.2014

PMCID:: PMC3891965

Abstract Article PDF–3.2M

Select item 264869718.

The neuropathic potential of anti-GM1 autoantibodies is regulated by the local glycolipid environment in mice

Kay N. Greenshields, Susan K. Halstead, Femke M.P. Zitman, Simon Rinaldi, Kathryn M. Brennan, Colin O’Leary, Luke H. Chamberlain, Alistair Easton, Jennifer Roxburgh, John Pediani, Koichi Furukawa, Keiko Furukawa, Carl S. Goodyear, Jaap J. Plomp, Hugh J. Willison

J Clin Invest. 2009 Mar 2; 119(3): 595–610. Published online 2009 Feb 16. doi: 10.1172/JCI37338

PMCID:: PMC2648697

Abstract Article PDF–4.3M

Select item 240865319.

Disruption of GM2/GD2 synthase gene resulted in overt expression of 9-O-acetyl GD3 irrespective of Tis21

Keiko Furukawa, Wei Aixinjueluo, Takeshi Kasama, Yuki Ohkawa, Michiko Yoshihara, Yusuke Ohmi, Orie Tajima, Akio Suzumura, Daiji Kittaka, Koichi Furukawa

J Neurochem. 2008 May; 105(3): 1057–1066. doi: 10.1111/j.1471-4159.2008.05232.x

PMCID:: PMC2408653

Abstract Article PDF–752K

Select item 216940220.

Initiation of Protein O Glycosylation by the Polypeptide GalNAcT-1 in Vascular Biology and Humoral Immunity

Mari Tenno, Kazuaki Ohtsubo, Fred K. Hagen, David Ditto, Alexander Zarbock, Patrick Schaerli, Ulrich H. von Andrian, Klaus Ley, Dzung Le, Lawrence A. Tabak, Jamey D. Marth

Mol Cell Biol. 2007 Dec; 27(24): 8783–8796. Published online 2007 Oct 8. doi: 10.1128/MCB.01204-07

PMCID:: PMC2169402

Abstract Article PDF–874K

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PMC Links for Gene (Select 14421) (56)
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Mus musculus beta-1,4-N-acetyl-galactosaminyl transferase 1 (B4galnt1), transcri...
Mus musculus beta-1,4-N-acetyl-galactosaminyl transferase 1 (B4galnt1), transcript variant 1, mRNA
gi|2697890070|ref|NM_008080.6|

Nucleotide

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