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Volume 5(2);  2024 Mar 1

Articles from this journal are generally available in PMC after a 6-month delay (embargo); however, the delay may vary at the discretion of the publisher.

In This Issue

Highlighted research articles
Blood Cancer Discov. 2024 Mar 1; 5(2): 80. doi: 10.1158/2643-3230.BCD-5-2-ITI
PMCID:
PMC10905507

In the Spotlight

The Siren Song of Synergy
Patrick D. Bhola, Anthony Letai
Blood Cancer Discov. 2024 Mar 1; 5(2): 81–82. Published online 2024 Feb 8. doi: 10.1158/2643-3230.BCD-24-0004
PMCID:
PMC10905523
Altered Oxidative Phosphorylation Confers Vulnerability on IDH1-Mutant Leukemia Cells: Is This Therapeutically Tractable?
David P. Steensma
Blood Cancer Discov. 2024 Mar 1; 5(2): 83–85. Published online 2024 Feb 8. doi: 10.1158/2643-3230.BCD-23-0255
PMCID:
PMC10905515

In Focus

Understanding Mechanisms of Response to CAR T-cell Therapy through Single-Cell Sequencing: Insights and Challenges
Nicholas J. Haradhvala, Marcela V. Maus
Blood Cancer Discov. 2024 Mar 1; 5(2): 86–89. Published online 2024 Feb 7. doi: 10.1158/2643-3230.BCD-23-0212
PMCID:
PMC10905509
Emerging Strategies for the Prevention of Immune Toxicities Associated with T cell–Engaging Cancer Therapies
Andrew Kowalski, Jill Lykon, Benjamin Diamond, David G. Coffey, Marcella Kaddoura, Francesco Maura, James E. Hoffman, Dickran Kazandjian, Ola Landgren
Blood Cancer Discov. 2024 Mar 1; 5(2): 90–94. Published online 2024 Jan 17. doi: 10.1158/2643-3230.BCD-23-0228
PMCID:
PMC10905506

Research BriefS

Synergistic Drug Combinations Promote the Development of Resistance in Acute Myeloid Leukemia
Emily Mason-Osann, Amy E. Pomeroy, Adam C. Palmer, Jerome T. Mettetal
Blood Cancer Discov. 2024 Mar 1; 5(2): 95–105. Published online 2024 Jan 16. doi: 10.1158/2643-3230.BCD-23-0067
PMCID:
PMC10905516

Research Brief

Baseline Serum Inflammatory Proteins Predict Poor CAR T Outcomes in Diffuse Large B-cell Lymphoma
Rawan G. Faramand, Sae Bom Lee, Michael D. Jain, Biwei Cao, Xuefeng Wang, Kai Rejeski, Marion Subklewe, Johannes F. Fahrmann, Neeraj Y. Saini, Samir M. Hanash, Yun Pyo Kang, Darwin Chang, Paolo C. Rodriguez, Erin A. Dean, Taiga Nishihori, Bijal D. Shah, Aleksandr Lazaryan, Julio Chavez, Farhad Khimani, Javier A. Pinilla-Ibarz, Marian Dam, Kayla M. Reid, Salvatore A. Corallo, Meghan Menges, Melanie Hidalgo Vargas, Jay K. Mandula, Brian A. Holliday, Christina A. Bachmeier, Kelly Speth, Qinghua Song, Mike Mattie, Frederick L. Locke, Marco L. Davila
Blood Cancer Discov. 2024 Mar 1; 5(2): 106–113. Published online 2024 Jan 8. doi: 10.1158/2643-3230.BCD-23-0056
PMCID:
PMC10905320

Research Article

IDH1-Mutant Preleukemic Hematopoietic Stem Cells Can Be Eliminated by Inhibition of Oxidative Phosphorylation
Niklas Landberg, Thomas Köhnke, Yang Feng, Yusuke Nakauchi, Amy C. Fan, Miles H. Linde, Daiki Karigane, Kelly Lim, Rahul Sinha, Luca Malcovati, Daniel Thomas, Ravindra Majeti
Blood Cancer Discov. 2024 Mar 1; 5(2): 114–131. Published online 2023 Dec 12. doi: 10.1158/2643-3230.BCD-23-0195
PMCID:
PMC10905513

Correction


Articles from Blood Cancer Discovery are provided here courtesy of American Association for Cancer Research