Volume 130(8); 2024 May 3

Articles from this journal are generally available in PMC after a 12-month delay (embargo); however, the delay may vary at the discretion of the publisher.

Perspective

Transforming post pandemic cancer services

Thomas Round, Lakshman Sethuraman, Mark Ashworth, Arnie Purushotham

Br J Cancer. 2024 May 3; 130(8): 1233–1238. Published online 2024 Mar 15. doi: 10.1038/s41416-024-02596-9

PMCID:: PMC11014976

Article PDF–449K

Review Article

Cyclin-dependent kinase 7 (CDK7) inhibitors as a novel therapeutic strategy for different molecular types of breast cancer

Xue Song, Chen Fang, Yan Dai, Yang Sun, Chang Qiu, Xiaojie Lin, Rui Xu

Br J Cancer. 2024 May 3; 130(8): 1239–1248. Published online 2024 Feb 14. doi: 10.1038/s41416-024-02589-8

PMCID:: PMC11014910

Currently embargoed: Free in PMC on Feb 14, 2025; PubMed

Articles

AHRR and SFRP2 in primary versus recurrent high-grade serous ovarian carcinoma and their prognostic implication

Nanna Monjé, Mihnea P. Dragomir, Bruno V. Sinn, Inga Hoffmann, Anuar Makhmut, Tincy Simon, Catarina A. Kunze, Jana Ihlow, Wolfgang D. Schmitt, Jonathan Pohl, Iris Piwonski, Sofya Marchenko, Carlotta Keunecke, Teodor G. Calina, Francesca Tiso, Hagen Kulbe, Caroline Kreuzinger, Dan Cacsire Castillo-Tong, Jalid Sehouli, Elena I. Braicu, Carsten Denkert, Silvia Darb-Esfahani, Kirsten Kübler, David Capper, Fabian Coscia, Markus Morkel, David Horst, Christine Sers, Eliane T. Taube

Br J Cancer. 2024 May 3; 130(8): 1249–1260. Published online 2024 Feb 9. doi: 10.1038/s41416-023-02550-1

PMCID:: PMC11014847

Article PDF–2.4M

CAnceR IN PreGnancy (CARING) – a retrospective study of cancer diagnosed during pregnancy in the United Kingdom

M. A. Baxter, M. Denholm, S. J. Kingdon, S. Kathirgamakarthigeyan, S. Parikh, R. Shakir, R. Johnson, H. Martin, M. Walton, W. Yao, A. Swan, C. Samuelson, X. Ren, A. Cooper, H-L Gray, S. Clifton, J. Ball, G. Gullick, M. Anderson, L. Dodd, H. Hayhurst, M. Salama, R. Shotton, F. Britton, T. Christodoulou, A. Abdul-Hamid, A. Eichholz, R. M. Evans, P. Wallroth, F. Gibson, K. Poole, M. Rowe, J. Harris, National Oncology Trainees Collaborative for Healthcare Research (NOTCH)

Br J Cancer. 2024 May 3; 130(8): 1261–1268. Published online 2024 Feb 21. doi: 10.1038/s41416-024-02605-x

PMCID:: PMC11014900

Article PDF–446K

Fluoropyrimidine type, patient age, tumour sidedness and mutation status as determinants of benefit in patients with metastatic colorectal cancer treated with EGFR monoclonal antibodies: individual patient data pooled analysis of randomised trials from the ARCAD database

C. S. Karapetis, H. Liu, M. J. Sorich, L. D. Pederson, E. Van Cutsem, T. Maughan, J. Y. Douillard, C. J. O’Callaghan, D. Jonker, C. Bokemeyer, A. Sobrero, C. Cremolini, B. Chibaudel, J. Zalcberg, R. Adams, M. Buyse, M. Peeters, T. Yoshino, A. de Gramont, Q. Shi

Br J Cancer. 2024 May 3; 130(8): 1269–1278. Published online 2024 Feb 24. doi: 10.1038/s41416-024-02604-y

PMCID:: PMC11015038

Article PDF–795K

Low-dose aspirin use and risk of ovarian cancer: a combined analysis from two nationwide studies in Denmark and Sweden

Guoqiao Zheng, Mette Tuxen Faber, Jiangrong Wang, Louise Baandrup, Rasmus Hertzum-Larsen, Karin Sundström, Susanne K. Kjær

Br J Cancer. 2024 May 3; 130(8): 1279–1285. Published online 2024 Feb 12. doi: 10.1038/s41416-024-02609-7

PMCID:: PMC11014981

Currently embargoed: Free in PMC on Feb 12, 2025; PubMed

Age at lung cancer diagnosis in females versus males who never smoke by race and ethnicity

Batel Blechter, Jason Y. Y. Wong, Li-Hsin Chien, Kouya Shiraishi, Xiao-Ou Shu, Qiuyin Cai, Wei Zheng, Bu-Tian Ji, Wei Hu, Mohammad L. Rahman, Hsin-Fang Jiang, Fang-Yu Tsai, Wen-Yi Huang, Yu-Tang Gao, Xijing Han, Mark D. Steinwandel, Gong Yang, Yihe G. Daida, Su-Ying Liang, Scarlett L. Gomez, Mindy C. DeRouen, W. Ryan Diver, Ananya G. Reddy, Alpa V. Patel, Loïc Le Marchand, Christopher Haiman, Takashi Kohno, Iona Cheng, I-Shou Chang, Chao Agnes Hsiung, Nathaniel Rothman, Qing Lan

Br J Cancer. 2024 May 3; 130(8): 1286–1294. Published online 2024 Feb 22. doi: 10.1038/s41416-024-02592-z

PMCID:: PMC11014844

Article PDF–546K

A prospective study of birth weight and prostate cancer risk and mortality in the Health Professionals Follow-up Study

Qinran Liu, Yiwen Zhang, Jane B. Vaselkiv, Lorelei A. Mucci, Edward L. Giovannucci, Elizabeth A. Platz, Siobhan Sutcliffe

Br J Cancer. 2024 May 3; 130(8): 1295–1303. Published online 2024 Feb 22. doi: 10.1038/s41416-024-02593-y

PMCID:: PMC11015033

Currently embargoed: Free in PMC on Feb 22, 2025; PubMed

Risk of cancer and serious disease in Danish patients with urgent referral for serious non-specific symptoms and signs of cancer in Funen 2014–2021

Rasmus Birkholm Grønnemose, Per Syrak Hansen, Søren Worsøe Laursen, Oke Gerke, Jakob Kjellberg, Jesper Lykkegaard, Clara Thye-Rønn, Poul Flemming Høilund-Carlsen, Peter Thye-Rønn

Br J Cancer. 2024 May 3; 130(8): 1304–1315. Published online 2024 Feb 26. doi: 10.1038/s41416-024-02620-y

PMCID:: PMC11014902

Article PDF–781K

HER2 expression and genOmic characterization of rESected brain metastases from colorectal cancer: the HEROES study

Alessandra Anna Prete, Valentina Angerilli, Francesca Bergamo, Valentina Vettore, Chiara De Toni, Rossana Intini, Krisida Cerma, Gianmarco Ricagno, Riccardo Cerantola, Eleonora Perissinotto, Antonio De Rosa, Carlotta Ceccon, Jessica Gasparello, Luca Denaro, Alberto D’Amico, Franco Chioffi, Elena Carcea, Matteo Fassan, Sara Lonardi

Br J Cancer. 2024 May 3; 130(8): 1316–1323. Published online 2024 Feb 12. doi: 10.1038/s41416-023-02569-4

PMCID:: PMC11014920

Article PDF–1.5M

ABCC4 suppresses glioblastoma progression and recurrence by restraining cGMP-PKG signalling

Jung-Ying Chiang, Sung-Tai Wei, Huan-Jui Chang, Der-Cherng Chen, Hwai-Lee Wang, Fu-Ju Lei, Kai-Yu Wei, Yen‐Chih Huang, Chi-Chung Wang, Chia-Hung Hsieh

Br J Cancer. 2024 May 3; 130(8): 1324–1336. Published online 2024 Feb 12. doi: 10.1038/s41416-024-02581-2

PMCID:: PMC11014854

Currently embargoed: Free in PMC on Feb 12, 2025; PubMed

IL-24 improves efficacy of CAR-T cell therapy by targeting stemness of tumor cells

Kai Zhang, Wenhao Hu, Feng Li, Chunli Wen, Lingxiao Zhou, Lei Zhang, Jingyao Lian, Shasha Liu, Shumin Wang, Yi Zhang

Br J Cancer. 2024 May 3; 130(8): 1337–1347. Published online 2024 Feb 12. doi: 10.1038/s41416-024-02601-1

PMCID:: PMC11015030

Currently embargoed: Free in PMC on Feb 12, 2025; PubMed

Germline predictors for bevacizumab induced hypertensive crisis in ECOG-ACRIN 5103 and BEATRICE

Fei Shen, Guanglong Jiang, Santosh Philips, Erica Cantor, Laura Gardner, Gloria Xue, Geneva Cunningham, Nawal Kassem, Anne O’Neill, David Cameron, Thomas M. Suter, Kathy D. Miller, George W. Sledge, Bryan P. Schneider

Br J Cancer. 2024 May 3; 130(8): 1348–1355. Published online 2024 Feb 12. doi: 10.1038/s41416-024-02602-0

PMCID:: PMC11014938

Currently embargoed: Free in PMC on Feb 12, 2025; PubMed

Stratifying ICIs-responsive tumor microenvironment in HCC: from parsing out immune-hypoxic crosstalk to clinically applicable MRI-radiomics models

Li-Na Song, Biao Wang, Jia-Liang Cai, Pei-Ling Zhang, Shi-Ping Chen, Zheng-Jun Zhou, Zhi Dai

Br J Cancer. 2024 May 3; 130(8): 1356–1364. Published online 2024 Feb 14. doi: 10.1038/s41416-023-02463-z

PMCID:: PMC11014931

Currently embargoed: Free in PMC on Feb 14, 2025; PubMed

Tumor Treating Fields (TTFields) combined with the drug repurposing approach CUSP9v3 induce metabolic reprogramming and synergistic anti-glioblastoma activity in vitro

Qiyu Cao, Annika Hajosch, Richard Eric Kast, Christopher Loehmann, Michal Hlavac, Pamela Fischer-Posovszky, Hannah Strobel, Mike-Andrew Westhoff, Markus D. Siegelin, Christian Rainer Wirtz, Marc-Eric Halatsch, Georg Karpel-Massler

Br J Cancer. 2024 May 3; 130(8): 1365–1376. Published online 2024 Feb 23. doi: 10.1038/s41416-024-02608-8

PMCID:: PMC11015043

Article PDF–2.1M

Capivasertib combines with docetaxel to enhance anti-tumour activity through inhibition of AKT-mediated survival mechanisms in prostate cancer

Cath Eberlein, Stuart C. Williamson, Lorna Hopcroft, Susana Ros, Jennifer I. Moss, James Kerr, Wytske M. van Weerden, Elza C. de Bruin, Shanade Dunn, Brandon Willis, Sarah J. Ross, Claire Rooney, Simon T. Barry

Br J Cancer. 2024 May 3; 130(8): 1377–1387. Published online 2024 Feb 23. doi: 10.1038/s41416-024-02614-w

PMCID:: PMC11014923

Article PDF–994K

Single-cell RNA sequencing reveals myeloid and T cell co-stimulation mediated by IL-7 anti-cancer immunotherapy

Hye Hyeon Eum, Dasom Jeong, Nayoung Kim, Areum Jo, Minsu Na, Huiram Kang, Yourae Hong, Jin-Sun Kong, Gi Heon Jeong, Seung-Ah Yoo, Hae-Ock Lee

Br J Cancer. 2024 May 3; 130(8): 1388–1401. Published online 2024 Feb 29. doi: 10.1038/s41416-024-02617-7

PMCID:: PMC11014989

Article PDF–20M

Inhibition of the AURKA/YAP1 axis is a promising therapeutic option for overcoming cetuximab resistance in colorectal cancer stem cells

Anxo Rio-Vilariño, Aiora Cenigaonandia-Campillo, Ana García-Bautista, Pedro A. Mateos-Gómez, Marina I. Schlaepfer, Laura del Puerto-Nevado, Oscar Aguilera, Laura García-García, Carlos Galeano, Irene de Miguel, Juana Serrano-López, Natalia Baños, María Jesús Fernández-Aceñero, Juan Carlos Lacal, Enzo Medico, Jesús García-Foncillas, Arancha Cebrián

Br J Cancer. 2024 May 3; 130(8): 1402–1413. Published online 2024 Mar 11. doi: 10.1038/s41416-024-02649-z