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Inhibition of NLRC4 inflammasome activation in LPS/flagellin-treated human THP-1 cells preincubated with LPS for 3 hrs followed by compound addition for 30 mins and further stimulated with flagellin for 90 min
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of NLRC4 inflammasome activation in LPS-primed human THP-1 cells infected in salmonella typhimurium assessed as reduction in caspase-1 activation at 0.1 to 10 uM for 30 mins followed by Salmonella infection and measured after 3.5 hrs by western blot analysis
Inhibition of NLRC4 inflammasome activation in LPS-primed human THP-1 cells infected in salmonella typhimurium assessed as reduction in IL-1beta release at 0.1 to 10 uM for 30 mins followed by Salmonella infection and measured after 3.5 hrs by western blot analysis
Inhibition of NLRC4 inflammasome activation in LPS-primed human THP-1 cells infected in salmonella typhimurium assessed as reduction in IL-1beta release in cell supernatant at 0.1 to 10 uM for 30 mins followed by Salmonella infection and measured after 3.5 hrs by ELISA
Inhibition of NLRC4 inflammasome activation in LPS-induced human THP-1 cells at 3 to 5uM for 40 mins followed by flagellin stimulation for 6 h by ELISA
Inhibition of NLRC4 inflammasome activation in LPS-induced human THP-1 cells at 1 uM for 40 mins followed by flagellin stimulation for 6 h by ELISA
Inhibition of NLRC4 in PMA-stimulated human THP-1 cells assessed as reduction in IL-1beta production at 5 to 15 uM pre-treated for 24 hrs followed by stimulation with LPS for 3 hrs and Salmonella typhimurium flagellin for 1 hr by ELISA analysis
Inhibition of NLRC4 inflammasome (unknown origin) activation in bone marrow derived macrophages assessed as inhibition of Salmonella-induced IL-1beta secretion at 5 uM by ELISA
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