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Antibacterial activity against Burkholderia cenocepacia assessed as inhibition of bacterial growth in presence of SPR741 by Muller hinton broth based microdilution assay
Assay data:5 Tested
SummaryPubMed Citation
Antibacterial activity against Burkholderia cenocepacia assessed as inhibition of bacterial growth by Muller hinton broth based microdilution assay
Inhibition of Burkholderia cenocepacia synthase CepI assessed as liberation of ACP thiol using SAM as substrate by DCPIP method
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Binding affinity to Burkholderia cenocepacia synthase CepI assessed as stabilization of protein in presence of trypsin at 50 uM by standard colorimetric trypsin assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed Citation
Inhibition of Burkholderia cenocepacia synthase CepI assessed as liberation of ACP thiol using SAM as substrate at 100 uM by DCPIP method
Assay data:2 Active, 2 Tested
Antimicrobial activity against multidrug-resistant Burkholderia cenocepacia K56-2 by microdilution broth method
Assay data:2 Tested
Antibacterial activity against gram-negative Burkholderia cenocepacia BC240 by CLSI method
Assay data:24 Tested
Antibacterial activity against Burkholderia cenocepacia 240 assessed as bacterial growth inhibition by susceptibility testing assay
Assay data:18 Tested
Antimicrobial activity against Burkholderia cenocepacia J2315 incubated for 18 hrs by microplate reader based assay
Assay data:1 Tested
Inhibition of Burkholderia cenocepacia HldA assessed as ATP depletion after 30 mins by luminescence assay
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Antibacterial activity against Burkholderia cenocepacia LMG16656 after 20 hrs by broth microdilution assay
Assay data:10 Tested
Antimicrobial activity against Burkholderia cenocepacia LMG16656 assessed as reduction of cell viability at 1 mM after 24 hrs by CTB staining
Assay data:3 Active, 3 Tested
Antimicrobial activity against Burkholderia cenocepacia LMG16656 assessed as reduction of cell viability at 1 mM incubated for 24 hrs post-biofilm growth by CTB staining
Antimicrobial activity against Burkholderia cenocepacia LMG16656 assessed as reduction of biofilm biomass at 1 mM incubated for 24 hrs post-biofilm growth by crystal violet staining
Antimicrobial activity against Burkholderia cenocepacia LMG16656 assessed as inhibition of biofilm formation at 1 mM after 24 hrs by crystal violet staining
Assay data:3 Tested
Inhibition of Burkholderia cenocepacia 07-34 beta-lactamase PenB1
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Activity at Burkholderia cenocepacia 07-34 beta-lactamase PenB1 expressed in Escherichia coli Top10 by UV-spectrophotometry
Assay data:1 Active, 13 Tested
Induction of Burkholderia cenocepacia 5007902 beta-lactamase PenB34 at 0.6 ug/ml in presence of cephalothin as substrate
Induction of Burkholderia cenocepacia 212 beta-lactamase PenB3 at 0.6 ug/ml in presence of cephalothin as substrate
Ratio of Kcat to Km for Burkholderia cenocepacia 07-34 beta-lactamase PenB1 expressed in Escherichia coli Top10
Assay data:13 Tested
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