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Primary qHTS assay for Inhibitors of ovarian cancer metastasis using an organotypic tumor microenvironment (TME) model.
Assay data:60 Active, 47 Activity ≤ 1 µM, 45897 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: KMS28PE_JCRB cell viability assay
Assay data:751 Active, 8 Activity ≤ 1 nM, 310 Activity ≤ 1 µM, 1912 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Depositor
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: MOLP8_DSMZ cell viability assay
Assay data:496 Active, 19 Activity ≤ 1 nM, 394 Activity ≤ 1 µM, 1912 Tested
Primary redox qHTS assay for identification of artifact compounds.
Assay data:19 Active, 16 Activity ≤ 1 µM, 5098 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Depositor
Primary Nanoluciferase (NLuc) qHTS assay for identification of artifact compounds.
Assay data:37 Active, 2 Activity ≤ 1 µM, 5098 Tested
Primary fluorescence-based thiol-reactive (MSTI) qHTS assay for identification of artifact compounds.
Assay data:494 Active, 184 Activity ≤ 1 µM, 5098 Tested
Primary firefly luciferase (FLuc) qHTS assay for identification of artifact compounds.
Assay data:75 Active, 14 Activity ≤ 1 µM, 5098 Tested
Primary qHTS Assay for Inhibitors of Recombinant Selenoprotein Glutathione Peroxidase 4 (GPX4)
Assay data:258 Active, 16 Activity ≤ 1 µM, 11046 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Primary qHTS Assay for Inhibitors of Recombinant Selenoprotein Glutathione Peroxidase 1 (GPX1)
Assay data:186 Active, 9 Activity ≤ 1 µM, 11353 Tested
Primary Screen for Target Class Profiling of Small Molecule Inhibitors of Methyltransferases
Assay data:968 Active, 24930 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Primary qHTS for Inhibitors of ATXN expression
Assay data:2593 Active, 3 Activity ≤ 1 nM, 2671 Activity ≤ 1 µM, 361713 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Suppression of hypoxia-induced upregulation of MMP9 expression in human MDA-MB-231 cells at 1 nM measured after 24 hrs in presence of IGF-1 by Western blot analysis
Assay data:1 Tested
SummaryPubMed Citation
Suppression of hypoxia-induced upregulation of MMP2 expression in human MDA-MB-231 cells at 1 nM measured after 24 hrs in presence of IGF-1 by Western blot analysis
Inhibition of hypoxia-induced activation of PI3K/Akt/mTOR signaling in human MDA-MB-231 side population cells at 1 nM measured after 24 hrs in presence of IGF-1 by Western blot analysis
Cytotoxicity against human MCF7 side population cells assessed as reduction in cell viability at 0.25 to 1 mM measured after 24 hrs by CCK-8 assay
Cytotoxicity against human MCF7 side population cells assessed as reduction in cell viability at 0.25 to 1 mM measured after 24 hrs under hypoxia condition by CCK-8 assay
Cytotoxicity against human MDA-MB-231 side population cells assessed as reduction in cell viability at 0.25 to 1 mM measured after 24 hrs by CCK-8 assay
Cytotoxicity against human MDA-MB-231 side population cells assessed as reduction in cell viability at 0.25 to 1 mM measured after 24 hrs under hypoxia condition by CCK-8 assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability at 0.25 to 1 mM measured after 24 hrs under hypoxia condition by CCK-8 assay
Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability at 0.25 to 1 mM measured after 24 hrs under hypoxia condition by CCK-8 assay
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