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Inhibition of rat liver SULT1A1-mediated oestradiol sulfonation incubated for 20 mins
Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 6 days by SRB assay
Assay data:16 Active, 1 Activity ≤ 1 nM, 11 Activity ≤ 1 µM, 17 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: OCIMY1_PLB cell viability assay
Assay data:408 Active, 25 Activity ≤ 1 nM, 317 Activity ≤ 1 µM, 1912 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Depositor
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: KMS26_JCRB cell viability assay
Assay data:699 Active, 23 Activity ≤ 1 nM, 366 Activity ≤ 1 µM, 1912 Tested
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: KMS21BM_JCRB cell viability assay
Assay data:650 Active, 358 Activity ≤ 1 nM, 751 Activity ≤ 1 µM, 1912 Tested
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: KMS20_JCRB cell viability assay
Assay data:588 Active, 31 Activity ≤ 1 nM, 546 Activity ≤ 1 µM, 1912 Tested
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: JJN3_DSMZ cell viability assay
Assay data:743 Active, 23 Activity ≤ 1 nM, 495 Activity ≤ 1 µM, 1912 Tested
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: Karpas620_DSMZ cell viability assay
Assay data:592 Active, 16 Activity ≤ 1 nM, 284 Activity ≤ 1 µM, 1912 Tested
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: Delta47_JCRB cell viability assay
Assay data:811 Active, 19 Activity ≤ 1 nM, 394 Activity ≤ 1 µM, 1912 Tested
Determination of IC50 values for inhibition of enzymatic assay of human HDAC6 with custom peptide substrate
Assay data:146 Active, 82 Activity ≤ 1 µM, 148 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Cytochrome P450 Family 2 Subfamily C Member 9 (CYP2C9) small molecule antagonists: luciferase reporter qHTS assay
Assay data:2931 Active, 3 Activity ≤ 1 nM, 133 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Cytochrome P450 family 2 subfamily C member 9 (CYP2C9) small molecule antagonists: luciferase cell-based qHTS assay
Assay data:2039 Active, 244 Activity ≤ 1 µM, 5242 Tested
Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay
Assay data:41 Active, 8 Activity ≤ 1 nM, 357 Activity ≤ 1 µM, 11292 Tested
qHTS assay to identify small molecule agonists of the estrogen receptor beta (ER-beta) signaling pathway: Summary
Assay data:149 Active, 1 Activity ≤ 1 nM, 52 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Inhibition of human recombinant carbonic anhydrase 12 preincubated for 15 mins at room temperature/6 hrs at 4 deg C by stopped-flow CO2 hydration assay
Assay data:22 Active, 22 Activity ≤ 1 µM, 22 Tested
Inhibition of human recombinant carbonic anhydrase 7 preincubated for 15 mins at room temperature/6 hrs at 4 deg C by stopped-flow CO2 hydration assay
Inhibition of human recombinant carbonic anhydrase 4 preincubated for 15 mins at room temperature/6 hrs at 4 deg C by stopped-flow CO2 hydration assay
Assay data:19 Active, 15 Activity ≤ 1 µM, 21 Tested
qHTS profiling of the MIPE4 collection as inhibitors of Plasmodium falciparum (HB3) proliferation
Assay data:57 Activity ≤ 1 nM, 344 Activity ≤ 1 µM, 2023 Tested
SummaryCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
qHTS profiling of the MIPE4 collection as inhibitors of Plasmodium falciparum (3D7) proliferation
Assay data:59 Activity ≤ 1 nM, 281 Activity ≤ 1 µM, 2023 Tested
qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway
Assay data:733 Active, 1 Activity ≤ 1 nM, 183 Activity ≤ 1 µM, 10486 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
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