Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Binding affinity towards human ADRB2 in an in vitro assay with cellular components measured by radioactivity method
Assay data:58 Active, 21 Activity ≤ 1 µM, 952 Tested
SummaryRelated BioAssays by Target
Agonist activity at human ADRB2 in an in vitro cell-based assay measured by time-resolved fluorescence resonance energy transfer method
Assay data:14 Active, 10 Activity ≤ 1 µM, 635 Tested
Compound was evaluated for inhibition of human ADRB1 in an in vitro assay measured by radioactivity method
Assay data:66 Active, 1 Activity ≤ 1 nM, 26 Activity ≤ 1 µM, 1195 Tested
Agonist activity at beta1 adrenoceptor (unknown origin) expressed in HEK293 cells assessed as cAMP accumulation incubated for 60 mins by microplate reader analysis
Assay data:2 Active, 2 Activity ≤ 1 µM, 21 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Agonist activity at beta2 adrenoceptor (unknown origin) expressed in HEK293 cells assessed as cAMP accumulation incubated for 60 mins by microplate reader analysis
Assay data:29 Active, 1 Activity ≤ 1 nM, 17 Activity ≤ 1 µM, 34 Tested
Inhibition Assay from Article : "Identification of two serine residues involved in agonist activation of the beta-adrenergic receptor."
Assay data:5 Active, 2 Activity ≤ 1 µM, 8 Tested
beta2 Adrenergic Receptor Binding Assay from Article 10.1021/jm800613s: "Synthesis of bivalent beta2-adrenergic and adenosine A1 receptor ligands."
Assay data:5 Active, 3 Activity ≤ 1 µM, 7 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Agonist activity at human beta2 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulation
Assay data:39 Active, 39 Activity ≤ 1 nM, 39 Activity ≤ 1 µM, 39 Tested
Agonist activity at human beta1 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulation
Assay data:39 Active, 2 Activity ≤ 1 nM, 38 Activity ≤ 1 µM, 39 Tested
Cytochrome P450 family 3 subfamily A member 4 (CYP3A4) small molecule antagonists: luciferase cell-based qHTS assay
Assay data:2147 Active, 1 Activity ≤ 1 nM, 377 Activity ≤ 1 µM, 5242 Tested
Displacement of [3H]DHA from inactive/G protein-uncoupled human beta2-AR expressed in CHO cell membranes assessed as intrinsic Kd by liquid scintillation counting
Assay data:9 Active, 1 Activity ≤ 1 nM, 6 Activity ≤ 1 µM, 11 Tested
Displacement of [3H]DHA from inactive/G protein-uncoupled human beta2-AR expressed in CHO cell membranes by liquid scintillation counting
Assay data:11 Active, 5 Activity ≤ 1 nM, 11 Activity ≤ 1 µM, 11 Tested
Agonist activity at human TAS2R4 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Agonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay
Agonist activity at human TAS2R39 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Agonist activity at human TAS2R47 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay
Agonist activity at human TAS2R49 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay
Agonist activity at human TAS2R60 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay
Agonist activity at human TAS2R40 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay
Agonist activity at human TAS2R41 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on