BioAssays, activity concentration at/below 1 uM for PubChem Compound ( - PubChem BioAssay - NCBI

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Items: 12

Select item 16482621.

Antiproliferative activity against human NCI-H1975 cells harboring FLAG-tagged MCM2 Q341A mutant assessed as reduction in cell viability incubated for 72 hrs by SRB assay

Source:: ChEMBL

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1648262

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 16482612.

Antiproliferative activity against human NCI-H1975 cells harboring FLAG-tagged MCM2 assessed as reduction in cell viability incubated for 72 hrs by SRB assay

Source:: ChEMBL

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1648261

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 16481973.

Antiproliferative activity against human NCI-H1975 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay

Source:: ChEMBL

Assay data:11 Active, 10 Activity ≤ 1 µM, 13 Tested

AID:: 1648197

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 16481964.

Antiproliferative activity against human CL1-5 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay

Source:: ChEMBL

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1648196

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 16481955.

Antiproliferative activity against human CL1-0 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay

Source:: ChEMBL

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1648195

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 16481946.

Antiproliferative activity against human PC9IR cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay

Source:: ChEMBL

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1648194

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 16481937.

Antiproliferative activity against human PC9 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay

Source:: ChEMBL

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1648193

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 6021198.

NOVARTIS: Antimalarial liver stage activity measured as reduction in Plasmodium yoelii schizont area in HepG2-A16-CD81 cells by immuno-fluorescence, and median schizont size at 10uM compound concentration

Source:: ChEMBL

Assay data:274 Active, 229 Activity ≤ 1 µM, 338 Tested

AID:: 602119

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 6021569.

Novartis GNF Liver Stage Dataset: Malariabox Annotation

Source:: GNF / Scripps Winzeler lab

Assay data:275 Active, 230 Activity ≤ 1 µM, 5697 Tested

AID:: 602156

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 44970510.

NOVARTIS: Cytotoxicity against human hepatocellular carcinoma cell line (Huh7)

Source:: ChEMBL

Assay data:399 Active, 59 Activity ≤ 1 µM, 5614 Tested

AID:: 449705

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 44970411.

NOVARTIS: Inhibition of Plasmodium falciparum W2 (drug-resistant) proliferation in erythrocyte-based infection assay

Source:: ChEMBL

Assay data:4616 Active, 9 Activity ≤ 1 nM, 3714 Activity ≤ 1 µM, 5614 Tested

AID:: 449704

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 44970312.

NOVARTIS: Inhibition of Plasmodium falciparum 3D7 (drug-susceptible) proliferation in erythrocyte-based infection assay

Source:: ChEMBL

Assay data:4209 Active, 3 Activity ≤ 1 nM, 3165 Activity ≤ 1 µM, 5614 Tested

AID:: 449703

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

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BioActivity

Active Compounds (12)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (2)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (12)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (11)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

Depositor Category

Literature Extraction (7)
BioAssays extracted from the literature
Other (5)
BioAssays deposited by other experimentalists

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BioAssays, activity concentration at/below 1 uM for PubChem Compo... (12)
BioAssays, activity concentration at/below 1 uM for PubChem Compound (Select 3585487)
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PubChem BioAssay
Parent Compound for PubChem Compound (Select 3585487) (1)
PubChem Compound
Taxonomy Links for PopSet (Select 966639429) (40)
Taxonomy
Nucleotide Links for PopSet (Select 1148968332) (3)
Nucleotide
Rhamphichthys apurensis voucher AUM:53707_T9916 16S ribosomal RNA gene, partial ...
Rhamphichthys apurensis voucher AUM:53707_T9916 16S ribosomal RNA gene, partial sequence; mitochondrial
gi|966639460|gb|KT166868.1|

Nucleotide

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