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ALPHA Screen Assay with TLX LBD from US Patent US20240067625: "SMALL-MOLECULE MODULATORS OF THE ORPHAN NUCLEAR RECEPTOR TLX"
Assay data:43 Active, 41 Activity ≤ 1 nM, 41 Activity ≤ 1 µM, 43 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Agonist activity at human Gal4-fused TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP16 assessed as repressor activity of receptor by measuring decrease in reporter activity measured after 14 hrs by Dual-Glo Luciferase assay
Assay data:5 Active, 2 Activity ≤ 1 µM, 7 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
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