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Primary qHTS to identify gynecologic anti-cancer compounds using libraries of approved drugs and bioactive compounds
Assay data:1106 Active, 14 Activity ≤ 1 nM, 6478 Activity ≤ 1 µM, 7578 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Depositor
qHTS assay to identify small molecule agonists of the estrogen receptor beta (ER-beta) signaling pathway - cell viability counter screen
Assay data:1136 Active, 121 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same Project
qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary
Assay data:433 Active, 1 Activity ≤ 1 nM, 156 Activity ≤ 1 µM, 10486 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary
Assay data:589 Active, 16 Activity ≤ 1 nM, 99 Activity ≤ 1 µM, 10486 Tested
qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary
Assay data:670 Active, 220 Activity ≤ 1 µM, 10486 Tested
qHTS assay for small molecule activators of the heat shock response signaling pathway
Assay data:51 Active, 56 Activity ≤ 1 µM, 9305 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS assay to identify aromatase inhibitors
Assay data:905 Active, 3 Activity ≤ 1 nM, 352 Activity ≤ 1 µM, 10486 Tested
qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line
Assay data:1084 Active, 8 Activity ≤ 1 nM, 330 Activity ≤ 1 µM, 10486 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway
Assay data:589 Active, 14 Activity ≤ 1 nM, 591 Activity ≤ 1 µM, 10486 Tested
qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway
Assay data:433 Active, 1 Activity ≤ 1 nM, 251 Activity ≤ 1 µM, 10486 Tested
qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway using the MDA cell line
Assay data:461 Active, 11 Activity ≤ 1 nM, 217 Activity ≤ 1 µM, 10486 Tested
qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway
Assay data:733 Active, 1 Activity ≤ 1 nM, 183 Activity ≤ 1 µM, 10486 Tested
qHTS assay for small molecule agonists of the p53 signaling pathway
Assay data:602 Active, 1 Activity ≤ 1 nM, 296 Activity ≤ 1 µM, 10488 Tested
Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin
Assay data:87 Active, 17 Activity ≤ 1 nM, 79 Activity ≤ 1 µM, 90 Tested
Binding affinity at AR
Assay data:17 Active, 13 Activity ≤ 1 µM, 17 Tested
Agonist activity at ERbeta expressed in HEK293 cells by transactivation assay
Assay data:15 Active, 17 Activity ≤ 1 µM, 17 Tested
Agonist activity at ERalpha expressed in HEK293 cells by transactivation assay
Assay data:8 Active, 1 Activity ≤ 1 nM, 17 Activity ≤ 1 µM, 17 Tested
Binding affinity at human recombinant ERbeta
Assay data:17 Active, 15 Activity ≤ 1 µM, 18 Tested
Binding affinity at human recombinant ERalpha
Assay data:13 Active, 5 Activity ≤ 1 µM, 17 Tested
Inhibitory activity against AR
Assay data:24 Active, 15 Activity ≤ 1 µM, 27 Tested
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