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Primary qHTS assay for inhibitors of the protease papain
Assay data:54 Active, 27 Activity ≤ 1 µM, 1272 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Validation qHTS for Identification of Calcium Integrin Binding protein 1 (CIB1) Competitor
Assay data:10 Active, 7 Activity ≤ 1 µM, 1277 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Displacement of [3H]muscimol from human GABAA receptor alpha1beta3gamma2 expressed in HEK293 TetR cell membranes after 1 hr by liquid scintillation counting method
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Positive allosteric modulation of human GABAA receptor alpha1beta2gamma2L expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induced current by measuring GABA EC50 at 2.5 uM incubated for 15 to 25 secs by two-electrode voltage clamp assay (Rvb = 4.5 uM)
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Primary qHTS to identify gynecologic anti-cancer compounds using libraries of approved drugs and bioactive compounds
Assay data:1106 Active, 14 Activity ≤ 1 nM, 6478 Activity ≤ 1 µM, 7578 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Depositor
qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen 2, blue channel
Assay data:237 Activity ≤ 1 µM, 2566 Tested
SummaryCompounds, activity ≤ 1 µMRelated BioAssays by Depositor
qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen2, ratio channel
Assay data:637 Active, 202 Activity ≤ 1 µM, 2566 Tested
qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 ratio channel
Assay data:502 Active, 187 Activity ≤ 1 µM, 2552 Tested
qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 blue channel
Assay data:612 Active, 225 Activity ≤ 1 µM, 2552 Tested
Displacement of [35S]TBPS from GABA-A receptor picrotoxin binding site in rat brain cortical membranes after 2 hrs by scintillation counting
Assay data:4 Active, 3 Activity ≤ 1 µM, 4 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS
Assay data:4037 Active, 2427 Activity ≤ 1 µM, 392548 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a
Assay data:31109 Active, 1 Activity ≤ 1 nM, 5166 Activity ≤ 1 µM, 353740 Tested
Displacement of [3H]ethynylpropylbicycloorthobenzoate from GABAA receptor from rat cortical membrane by scintillation counting in presence of 1 uM GABA
Assay data:9 Active, 2 Activity ≤ 1 µM, 18 Tested
The concentration required to inhibit 50% of binding of [35S]TBPS to Gamma-aminobutyric acid A receptor to rat whole brain membranes.
Assay data:49 Active, 37 Activity ≤ 1 µM, 50 Tested
Inhibition of binding of tert-butyl bicyclophosphorothionate ([35 S]TBPS) at Gamma-aminobutyric acid A receptor from rat whole brain membranes
Assay data:16 Active, 10 Activity ≤ 1 µM, 16 Tested
Inhibition of [35S]TBPS binding to GABA-A receptor in rat cerebral cortex.
Assay data:12 Active, 2 Activity ≤ 1 µM, 22 Tested
Concentration required to potentiate GABA-evoked currents in voltage-clamped bovine chromaffin cells by 300%
Assay data:20 Active, 15 Activity ≤ 1 µM, 21 Tested
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