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Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: luciferase reporter qHTS assay
Assay data:2934 Active, 132 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Cytochrome P450 Family 2 Subfamily C Member 19 (CYP2C19) small molecule antagonists: luciferase reporter qHTS assay
Assay data:3508 Active, 4 Activity ≤ 1 nM, 319 Activity ≤ 1 µM, 9667 Tested
Agonist activity at human estrogen receptor-beta by yeast two-hybrid assay in presence of SRC1
Assay data:4 Active, 2 Activity ≤ 1 µM, 4 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line
Assay data:1084 Active, 8 Activity ≤ 1 nM, 330 Activity ≤ 1 µM, 10486 Tested
Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assay
Assay data:31 Active, 20 Activity ≤ 1 µM, 31 Tested
Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assay
Inhibition of human carbonic anhydrase 7 preincubated for 15 mins by CO2 hydration stopped-flow assay
Assay data:36 Active, 21 Activity ≤ 1 µM, 38 Tested
Inhibition of human carbonic anhydrase 9 preincubated for 15 mins by CO2 hydration stopped-flow assay
Assay data:30 Active, 22 Activity ≤ 1 µM, 31 Tested
Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration stopped-flow assay
Assay data:31 Active, 24 Activity ≤ 1 µM, 31 Tested
Inhibition of human carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration stopped-flow assay
Assay data:36 Active, 29 Activity ≤ 1 µM, 38 Tested
qHTS assay for small molecule disruptors of the mitochondrial membrane potential
Assay data:1817 Active, 1 Activity ≤ 1 nM, 393 Activity ≤ 1 µM, 10486 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
DSSTox (NCTRER) National Center for Toxicological Research Estrogen Receptor Binding Database
Assay data:131 Active, 232 Tested
SummaryCompounds, ActivePubMed Citation
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