Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Compound was evaluated for inhibition of human ACHE in an vitro cell free assay measured by absorbance method
Assay data:10 Active, 5 Activity ≤ 1 µM, 73 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Assay data:31 Active, 15 Activity ≤ 1 µM, 927 Tested
Human butyrylcholinesterase (Hydrolases)
Assay data:5 Active, 5 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Human acetylcholinesterase (Cartwright blood group) (Hydrolases)
Assay data:12 Active, 12 Tested
Inhibition of Torpedo californica eel AChE using acetylthiocholine/DTNB as substrate preincubated for 10 mins followed by substrate addition measured every 30 secs for 30 mins by Ellmans method
Assay data:55 Active, 3 Activity ≤ 1 nM, 47 Activity ≤ 1 µM, 58 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Inhibition of human CYP3A4 assessed as ratio of IC50 in absence of NADPH to IC50 for presence of NADPH using 7-benzyloxyquinoline as substrate after 30 mins
Assay data:155 Active, 221 Tested
Inhibition of human CYP3A4 assessed as ratio of IC50 in absence of NADPH to IC50 for presence of NADPH using diethoxyfluorescein as substrate after 30 mins
Assay data:138 Active, 221 Tested
Inhibition of human CYP2D6 assessed as ratio of IC50 in absence of NADPH to IC50 for presence of NADPH using 4-methylaminoethyl-7-methoxycoumarin as substrate after 30 mins
Assay data:160 Active, 221 Tested
Inhibition of human CYP2C9 assessed as ratio of IC50 in absence of NADPH to IC50 for presence of NADPH using 7-methoxy-4-trifluoromethylcoumarin-3-acetic acid as substrate after 30 mins
Assay data:163 Active, 221 Tested
Inhibition of human CYP1A2 assessed as ratio of IC50 in absence of NADPH to IC50 for presence of NADPH using ethoxyresorufin as substrate after 30 mins
Assay data:162 Active, 221 Tested
qHTS Validation Assay for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails
Assay data:186 Active, 3 Activity ≤ 1 nM, 104 Activity ≤ 1 µM, 1280 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Inhibition of anticholinesterase activity by their ability to inactivate human serum butyrylcholinesterase
Assay data:5 Active, 1 Activity ≤ 1 µM, 5 Tested
Concentration required to inhibit hydrolytic activity of bovine erythrocyte acetylcholinesterase by 50%
Assay data:4 Active, 2 Activity ≤ 1 µM, 9 Tested
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on