BioAssays, Active for PubChem Compound (Select 33113) - PubChem BioAssay - NCBI

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Items: 9

Select item 18633161.

Inhibition of recombinant human RAD51/p53 (unknown origin) interaction at 200 uM measured by ELISA assay

Source:: ChEMBL

Assay data:6 Active, 6 Tested

AID:: 1863316

Summary Compounds, Active PubMed Citation

Select item 16148832.

Binding affinity to CK2alpha (unknown origin) at 500 uM by STD-based NMR spectroscopy

Source:: ChEMBL

Protein Target:: Casein kinase II subunit alpha

Assay data:3 Active, 3 Tested

AID:: 1614883

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 14132903.

Binding affinity to 1H/13C-Ile HSP90alpha CTD (unknown origin) at 2.5 mM by Methyl-TROSY 15N HSQC spectrum analysis

Source:: ChEMBL

Protein Target:: Heat shock protein HSP 90-alpha

Assay data:1 Active, 1 Tested

AID:: 1413290

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 13465994.

Human TRPM4 (Transient Receptor Potential channels)

Source:: IUPHAR/BPS Guide to PHARMACOLOGY

Protein Target:: transient receptor potential cation channel subfamily M member 4 isoform 2

Assay data:12 Active, 12 Tested

AID:: 1346599

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 9776115.

Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB

Source:: Shanghai Institute of Organic Chemistry

Protein Targets:: Chain 1, Cell division protein ftsZ; ...
Total:: 2972

Assay data:3916 Active, 206 Activity ≤ 1 nM, 1830 Activity ≤ 1 µM, 3916 Tested

AID:: 977611

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Depositor Related BioAssays by Target

Select item 9776106.

Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB

Source:: Shanghai Institute of Organic Chemistry

Protein Targets:: Chain 1, Beta-galactosidase; ...
Total:: 3355

Assay data:3598 Active, 421 Activity ≤ 1 nM, 2233 Activity ≤ 1 µM, 3598 Tested

AID:: 977610

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Depositor Related BioAssays by Target

Select item 1079017.

Inhibitory constant against rat kidney Methionine adenosyltransferase II

Source:: ChEMBL

Protein Target:: S-adenosylmethionine synthase isoform type-2

Assay data:1 Active, 6 Tested

AID:: 107901

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 1077438.

Inhibitory constant against rat Methionine adenosyltransferase was reported

Source:: ChEMBL

Protein Targets:: S-adenosylmethionine synthase isoform type-1; ...
Total:: 2

Assay data:1 Active, 5 Tested

AID:: 107743

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 18119.

Experimentally measured binding affinity data derived from PDB

Source:: Shanghai Institute of Organic Chemistry

Protein Targets:: Chain 1, Chymotrypsinogen A; ...
Total:: 3073

Assay data:3073 Active, 3073 Tested

AID:: 1811

Summary Compounds, Active PubMed Citation Related BioAssays by Target

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Target

Proteins (4)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (9)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (2)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (2)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (2)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

Depositor Category

Literature Extraction (9)
BioAssays extracted from the literature

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BioAssays, Active for PubChem Compound (Select 33113) (9)
PubChem BioAssay
Taxonomy Links for Protein (Select 12140345) (1)
Taxonomy
Homo sapiens ABCA1 gene for alternative protein ABCA1, isolate 143879
Homo sapiens ABCA1 gene for alternative protein ABCA1, isolate 143879
gi|444738516|emb|HF583827.1|

Nucleotide
ATP-binding cassette transporter A1 [Homo sapiens]
ATP-binding cassette transporter A1 [Homo sapiens]
gi|219883491|dbj|BAH10664.1|

Protein

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