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Nuclear factor erythroid 2-related factor 2/antioxidant responsive element (Nrf2/ARE) small molecule agonists: qHTS cell viability counter screen in human keratinocytes
Assay data:683 Active, 47 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same Project
Human Ether-a-go-go-Related Gene (hERG) channel small molecule antagonists: fluorescence cell-based qHTS assay
Assay data:704 Active, 81 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: luciferase reporter qHTS assay
Assay data:2934 Active, 132 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Cytochrome P450 Family 2 Subfamily C Member 9 (CYP2C9) small molecule antagonists: luciferase reporter qHTS assay
Assay data:2931 Active, 3 Activity ≤ 1 nM, 133 Activity ≤ 1 µM, 9667 Tested
Cytochrome P450 Family 2 Subfamily C Member 19 (CYP2C19) small molecule antagonists: luciferase reporter qHTS assay
Assay data:3508 Active, 4 Activity ≤ 1 nM, 319 Activity ≤ 1 µM, 9667 Tested
Human pregnane X receptor (PXR) small molecule agonists: Summary
Assay data:2076 Active, 9667 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Same Project
Progesterone receptor (PR) small molecule antagonists, qHTS assay: Summary
Assay data:1059 Active, 9667 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Human pregnane X receptor (PXR) small molecule agonists, qHTS assay
Assay data:2218 Active, 1 Activity ≤ 1 nM, 106 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS assay to identify small molecule agonists of the progesterone receptor (PR) signaling pathway - cell viability counter screen
Assay data:458 Active, 3 Activity ≤ 1 nM, 233 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule antagonists of the progesterone receptor (PR) signaling pathway
Assay data:724 Active, 1 Activity ≤ 1 nM, 121 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule antagonists of the estrogen receptor beta (ER-beta) signaling pathway: Summary
Assay data:593 Active, 9667 Tested
qHTS assay to identify small molecule antagonists of the thyroid stimulating hormone receptor (TSHR) signaling pathway: Summary
Assay data:316 Active, 6 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line in the presence of 0.5 nM R1881: Summary
Assay data:1108 Active, 2 Activity ≤ 1 nM, 246 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule antagonists of the thyroid stimulating hormone receptor (TSHR) signaling pathway
Assay data:205 Active, 1 Activity ≤ 1 nM, 56 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS assay to identify small molecule antagonists of the estrogen receptor beta (ER-beta) signaling pathway
Assay data:464 Active, 1 Activity ≤ 1 nM, 65 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line in the presence of 0.5 nM R1881
Assay data:1453 Active, 4 Activity ≤ 1 nM, 292 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule agonists of H2AX: Summary
Assay data:519 Active, 48 Activity ≤ 1 µM, 9667 Tested
qHTS RealTime-Glo MT Cell Viability Assay in HEK293 cells - 16 hour
Assay data:835 Active, 102 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Depositor
A CellTox Green Cytotoxicity Assay to monitor cytotoxicity in HEK293 cells - 40 hour
Assay data:848 Active, 77 Activity ≤ 1 µM, 9667 Tested
CCRIS carcinogenicity studies
Assay data:1139 Active, 1767 Tested
SummaryCompounds, Active
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