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G protein-coupled receptor (GPCR) small molecule agonists, calcium flux assay: HEK293 wild type cell line counter screen
Assay data:47 Active, 1 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same Project
Human kisspeptin (KISS1R) small molecule agonists, calcium flux assay in KISS1R-HEK293 cells
Assay data:55 Active, 2 Activity ≤ 1 nM, 10 Activity ≤ 1 µM, 9667 Tested
Human gonadotropin-releasing hormone receptor (GnRHR) small molecule agonists, calcium flux assay in GnRHR-HEK293 cells
Assay data:169 Active, 2 Activity ≤ 1 nM, 27 Activity ≤ 1 µM, 9667 Tested
Cytochrome P450 Family 2 Subfamily C Member 9 (CYP2C9) small molecule antagonists: luciferase reporter qHTS assay
Assay data:2931 Active, 3 Activity ≤ 1 nM, 133 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Cytochrome P450 Family 2 Subfamily C Member 19 (CYP2C19) small molecule antagonists: luciferase reporter qHTS assay
Assay data:3508 Active, 4 Activity ≤ 1 nM, 319 Activity ≤ 1 µM, 9667 Tested
Thyrotropin-releasing hormone receptor (TRHR) small molecule antagonists: Summary
Assay data:130 Active, 9667 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Thyrotropin-releasing hormone receptor (TRHR) small molecule agonists: Summary
Assay data:94 Active, 9667 Tested
Caspase-3/7 induction in HepG2 cells by small molecules, qHTS cell viability counter screen
Assay data:693 Active, 37 Activity ≤ 1 µM, 9667 Tested
Caspase-3/7 induction in CHO-K1 cells by small molecules, qHTS cell viability counter screen
Assay data:1380 Active, 82 Activity ≤ 1 µM, 9667 Tested
Human pregnane X receptor (PXR) small molecule agonists, qHTS cell viability counter screen
Assay data:873 Active, 64 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule agonists of the thyrotropin-releasing hormone receptor (TRHR) signaling pathway
Assay data:85 Active, 5 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS assay to identify small molecule antagonists of the thyrotropin-releasing hormone receptor (TRHR) signaling pathway
Assay data:81 Active, 11 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule antagonists of the thyroid stimulating hormone receptor (TSHR) signaling pathway: Summary
Assay data:316 Active, 6 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway in the presence of an antagonist - cell viability counter screen
Assay data:564 Active, 27 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule antagonists of the thyroid stimulating hormone receptor (TSHR) signaling pathway
Assay data:205 Active, 1 Activity ≤ 1 nM, 56 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway in the presence of an antagonist - cell viability counter screen
Assay data:756 Active, 46 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line in the presence of 0.5 nM R1881 - cell viability counter screen
Assay data:369 Active, 41 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line in the presence of 0.1 nM 17-beta-estradiol - cell viability counter screen
Assay data:327 Active, 34 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule agonists of H2AX: Summary
Assay data:519 Active, 48 Activity ≤ 1 µM, 9667 Tested
A CellTox Green Cytotoxicity Assay to monitor cytotoxicity in HepG2 cells - 8 hour
Assay data:390 Active, 34 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Depositor
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