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p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter screen
Assay data:213 Active, 2 Activity ≤ 1 nM, 241 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same Project
p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: qHTS cell viability counter screen
Assay data:214 Active, 153 Activity ≤ 1 µM, 9667 Tested
p53 small molecule agonists, cell-based qHTS assay with human liver microsomes: qHTS cell viability counter screen
Assay data:300 Active, 138 Activity ≤ 1 µM, 9667 Tested
Nuclear factor erythroid 2-related factor 2/antioxidant responsive element (Nrf2/ARE) small molecule agonists, luciferase reporter gene qHTS assay in human keratinocytes: Summary
Assay data:1038 Active, 9667 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Same Project
G protein-coupled receptor (GPCR) small molecule agonists, calcium flux assay: HEK293 wild type cell line counter screen
Assay data:47 Active, 1 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 9667 Tested
Human kisspeptin (KISS1R) small molecule agonists, calcium flux assay in KISS1R-HEK293 cells
Assay data:55 Active, 2 Activity ≤ 1 nM, 10 Activity ≤ 1 µM, 9667 Tested
Human gonadotropin-releasing hormone receptor (GnRHR) small molecule agonists, calcium flux assay in GnRHR-HEK293 cells
Assay data:169 Active, 2 Activity ≤ 1 nM, 27 Activity ≤ 1 µM, 9667 Tested
Nuclear factor erythroid 2-related factor 2/antioxidant responsive element (Nrf2/ARE) small molecule agonists: luciferase reporter gene qHTS assay in human keratinocytes
Assay data:1099 Active, 1 Activity ≤ 1 nM, 143 Activity ≤ 1 µM, 9667 Tested
Nuclear factor erythroid 2-related factor 2/antioxidant responsive element (Nrf2/ARE) small molecule agonists: qHTS cell viability counter screen in human keratinocytes
Assay data:683 Active, 47 Activity ≤ 1 µM, 9667 Tested
Cytochrome P450 Family 3 Subfamily A Member 4 (CYP3A4) small molecule antagonists: luciferase reporter qHTS assay
Assay data:1792 Active, 248 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Human Ether-a-go-go-Related Gene (hERG) channel small molecule antagonists: fluorescence cell-based qHTS assay
Assay data:704 Active, 81 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Cytochrome P450 Family 2 Subfamily C Member 9 (CYP2C9) small molecule antagonists: luciferase reporter qHTS assay
Assay data:2931 Active, 3 Activity ≤ 1 nM, 133 Activity ≤ 1 µM, 9667 Tested
Cytochrome P450 Family 2 Subfamily C Member 19 (CYP2C19) small molecule antagonists: luciferase reporter qHTS assay
Assay data:3508 Active, 4 Activity ≤ 1 nM, 319 Activity ≤ 1 µM, 9667 Tested
Cytochrome P450 Family 2 Subfamily D Member 6 (CYP2D6) small molecule antagonists: luciferase reporter qHTS assay
Assay data:2225 Active, 268 Activity ≤ 1 µM, 9667 Tested
Thyrotropin-releasing hormone receptor (TRHR) small molecule antagonists: Summary
Assay data:130 Active, 9667 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Caspase-3/7 induction in CHO-K1 cells by small molecules, qHTS assay: Summary
Assay data:221 Active, 9667 Tested
Caspase-3/7 induction in HepG2 cells by small molecules, qHTS assay: Summary
Assay data:415 Active, 9667 Tested
Human pregnane X receptor (PXR) small molecule agonists: Summary
Assay data:2076 Active, 9667 Tested
Thyrotropin-releasing hormone receptor (TRHR) small molecule agonists: Summary
Assay data:94 Active, 9667 Tested
Human pregnane X receptor (PXR) small molecule agonists, qHTS assay
Assay data:2218 Active, 1 Activity ≤ 1 nM, 106 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
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