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Primary screen in NF54 nanoGlo assay, in single point, at 2uM, 72h
Assay data:147432 Tested
Summary
Cell-based high throughput primary assay to identify activators of GPR151
Assay data:6756 Active, 646675 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Target
Luminescence cell-based high throughput primary assay to identify inhibitors of TEAD-YAP interaction.
Assay data:9273 Active, 641570 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of microphthalmia-associated transcription factor (MITF)
Assay data:5861 Active, 646275 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
AlphaScreen-based biochemical high throughput primary assay to identify activators of the E3 ligase (FBW7).
Assay data:853 Active, 645212 Tested
SummaryCompounds, ActivePubMed Citation
Inhibition of human recombinant N-terminal histidine tagged LSD1 expressed in Escherichia coli BL21 (DE3) assessed as production of H2O2 using H3K4me2 (1 to 21 amino acid residues) as substrate at 10 uM by chemiluminescence assay
Assay data:32 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of LSD1 in human Calu6 cells assessed as increase in H3K4me2 at 10 uM after 48 hrs by Western blot method relative to control
Inhibition of LSD1 in human Calu6 cells assessed as increase in H3K4me2 at 10 uM after 24 hrs by Western blot method relative to control
Assay data:6 Active, 26 Tested
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