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Anti-inflammatory activity in murine RAW264.7 cells assessed as inhibition of LPS-induced NO production
Assay data:2 Active, 6 Tested
SummaryCompounds, ActivePubMed Citation
Primary qHTS assay for inhibitors of human arachidonate 12S-lipoxygenase (ALOX12): Round 2
Assay data:6069 Active, 5332 Activity ≤ 1 µM, 575118 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Validation qHTS for agonist of cAMP-regulated guanine nucleotide exchange factor 4 (EPAC2)
Assay data:41 Active, 124 Activity ≤ 1 µM, 15613 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Validation qHTS for antagonist of cAMP-regulated guanine nucleotide exchange factor 4 (EPAC2)
Assay data:265 Active, 171 Activity ≤ 1 µM, 15637 Tested
Validation qHTS for agonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1)
Assay data:160 Active, 22 Activity ≤ 1 µM, 15634 Tested
Validation qHTS for antagonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1)
Assay data:115 Active, 91 Activity ≤ 1 µM, 15634 Tested
qHTS Assay for Foot and Mouth Disease Virus Antivirals: Primary Screen against the MLPCN compound library
Assay data:1964 Active, 408697 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal
Assay data:316 Active, 7162 Tested
qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): Viability assay - alamar blue signal for LCMV Primary Screen
Assay data:468 Active, 7162 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Target
qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen
Assay data:588 Active, 7162 Tested
qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal
Assay data:239 Active, 7162 Tested
Inhibition of mushroom tyrosinase activity using L-DOPA as substrate at 100 uM after 30 mins
Assay data:25 Tested
SummaryPubMed Citation
Inhibition of mushroom tyrosinase activity using L-DOPA as substrate at 10 uM after 30 mins
Inhibition of mushroom tyrosinase activity using L-tyrosine as substrate at 100 uM after 30 mins
Inhibition of mushroom tyrosinase activity using L-tyrosine as substrate at 10 uM after 30 mins
Cytotoxicity against theophylline-stimulated mouse B16-4A5 cells assessed as cell viability at 100 uM after 72 hrs by MTT assay relative to control
Assay data:15 Tested
Cytotoxicity against theophylline-stimulated mouse B16-4A5 cells assessed as cell viability at 30 uM after 72 hrs by MTT assay relative to control
Cytotoxicity against theophylline-stimulated mouse B16-4A5 cells assessed as cell viability at 10 uM after 72 hrs by MTT assay relative to control
Assay data:24 Tested
Cytotoxicity against theophylline-stimulated mouse B16-4A5 cells assessed as cell viability at 3 uM after 72 hrs by MTT assay relative to control
Antimelanogenic activity in theophylline-stimulated mouse B16-4A5 cells assessed as inhibition of melanogenesis at 100 uM after 72 hrs relative to control
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