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Half life in rat at 10 mg/kg
Assay data:6 Tested
SummaryPubMed Citation
AUC in rat at 10 mg/kg
Cmax in rat at 10 mg/kg
Assay data:6 Active, 5 Activity ≤ 1 µM, 6 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Oral bioavailability in rat at 10 mg/kg
Solubility in aqueous buffer at pH 7.4
Assay data:7 Tested
Solubility in aqueous buffer at pH 2.0
Metabolic stability to human liver microsomes assessed as half life
Antiproliferative activity against human SKOV3 cells
Assay data:3 Active, 3 Activity ≤ 1 µM, 7 Tested
Inhibition of EGFR
Assay data:21 Active, 20 Activity ≤ 1 µM, 22 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
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