BioAssays for PubChem Compound (Select 356285) - PubChem BioAssay - NCBI

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Select item 19189691.

Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress

Source:: ICCB-Longwood Screening Facility, Harvard Medical School

Assay data:281 Active, 189401 Tested

AID:: 1918969

Summary Compounds, Active

Select item 17948082.

Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL).

Source:: University of Kansas High Throughput Screening Laboratory

Assay data:523 Active, 206263 Tested

AID:: 1794808

Summary Compounds, Active PubMed Citation

Select item 16712023.

Alphascreen assay for small molecules abrogating mHTT-CaM Interaction

Source:: University of Kansas High Throughput Screening Laboratory

Protein Target:: Huntingtin

Assay data:6896 Active, 193105 Tested

AID:: 1671202

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 15086024.

Cell-based high throughput primary assay to identify activators of GPR151

Source:: The Scripps Research Institute Molecular Screening Center

Protein Target:: G-protein coupled receptor 151; G-protein coupled receptor PGR7; GPCR-2037; Galanin receptor 4; Galanin-receptor-like protein; GalRL

Assay data:6756 Active, 646675 Tested

AID:: 1508602

Summary Compounds, Active Related BioAssays by Depositor Related BioAssays by Target

Select item 12594235.

Primary cell-based high-throughput screening assay for identification of small molecule agonists of Aedes aegypti NPYLR7 [Small Molecule Inhibitors of Mosquito Biting Behavior]

Source:: Fisher Drug Discovery Resource Center

Assay data:412 Active, 270665 Tested

AID:: 1259423

Summary Compounds, Active PubMed Citation Related BioAssays by Depositor

Select item 12594226.

Luminescence cell-based high throughput primary assay to identify inhibitors of TEAD-YAP interaction.

Source:: The Scripps Research Institute Molecular Screening Center

Protein Target:: transcriptional coactivator YAP1 isoform 1

Assay data:9273 Active, 641570 Tested

AID:: 1259422

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 12593987.

human cGAS chemiluminescence screen

Source:: Fisher Drug Discovery Resource Center

Protein Target:: Cyclic GMP-AMP synthase

Assay data:234 Active, 287414 Tested

AID:: 1259398

Summary Compounds, Active Related BioAssays by Depositor Related BioAssays by Target

Select item 12593978.

mouse cGAS RapidFire screen

Source:: Fisher Drug Discovery Resource Center

Protein Target:: Cyclic GMP-AMP synthase

Assay data:231 Active, 125931 Tested

AID:: 1259397

Summary Compounds, Active PubMed Citation Related BioAssays by Depositor Related BioAssays by Target

Select item 12593749.

AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of microphthalmia-associated transcription factor (MITF)

Source:: The Scripps Research Institute Molecular Screening Center

Protein Target:: microphthalmia-associated transcription factor isoform 9

Assay data:5861 Active, 646275 Tested

AID:: 1259374

Summary Compounds, Active PubMed Citation Related BioAssays by Depositor Related BioAssays by Target

Select item 125935410.

Small-molecule inhibitors of ST2 (IL1RL1)

Source:: Paczesny and Yang Labs, IUPUI and University of Michigan

Protein Target:: Chain B, Interleukin-1 receptor-like 1

Assay data:1825 Active, 77700 Tested

AID:: 1259354

Summary Compounds, Active Related BioAssays by Target

Select item 125931011.

AlphaScreen-based biochemical high throughput primary assay to identify activators of the E3 ligase (FBW7).

Source:: The Scripps Research Institute Molecular Screening Center

Assay data:853 Active, 645212 Tested

AID:: 1259310

Summary Compounds, Active PubMed Citation

Select item 122490512.

High-throughput screen for inhibitors of the GIV GBA-motif interaction with Galpha-i G protein subunits

Source:: ICCB-Longwood Screening Facility, Harvard Medical School

Protein Targets:: Guanine nucleotide-binding protein G(i) subunit alpha-3; ...
Total:: 2

Assay data:879 Active, 206873 Tested

AID:: 1224905

Summary Compounds, Active Related BioAssays by Depositor Related BioAssays by Target

Select item 72071713.

Chemical Probes of Kaposi's Sarcoma Herpes Virus Latent Infection

Source:: ICCB-Longwood Screening Facility, Harvard Medical School

Assay data:152 Active, 51130 Tested

AID:: 720717

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 72064114.

A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus

Source:: ICCB-Longwood Screening Facility, Harvard Medical School

Protein Target:: anion-binding protein

Assay data:902 Active, 168808 Tested

AID:: 720641

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 58851915.

A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities

Source:: ICCB-Longwood Screening Facility, Harvard Medical School

Protein Target:: Chain A, Genome polyprotein

Assay data:1006 Active, 152580 Tested

AID:: 588519

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 54029916.

A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis

Source:: ICCB-Longwood Screening Facility, Harvard Medical School

Protein Target:: 1,4-dihydroxy-2-naphthoyl-CoA synthase

Assay data:440 Active, 103205 Tested

AID:: 540299

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 50477017.

A screen for compounds that inhibit replication of Vibrio cholerae chromosome II

Source:: ICCB-Longwood Screening Facility, Harvard Medical School

Protein Target:: hypothetical protein VC_A0002

Assay data:352 Active, 132739 Tested

AID:: 504770

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 49303318.

A screen for compounds that inhibit the bacterial siderophore biosynthetic enzyme MbtI

Source:: ICCB-Longwood Screening Facility, Harvard Medical School

Protein Target:: Salicylate synthase

Assay data:931 Active, 104781 Tested

AID:: 493033

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 49296719.

A screen for compounds that inhibit the CapD enzyme of Bacillus anthracis

Source:: ICCB-Longwood Screening Facility, Harvard Medical School

Protein Target:: gamma-glutamyltranspeptidase (plasmid)

Assay data:320 Active, 139468 Tested

AID:: 492967

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 48539520.

A screen for compounds that inhibit the activity of Staphylococcus aureus DNA helicase

Source:: ICCB-Longwood Screening Facility, Harvard Medical School

Protein Target:: replicative DNA helicase

Assay data:55 Active, 116258 Tested

AID:: 485395

Summary Compounds, Active PubMed Citation Related BioAssays by Target

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Target

Proteins (16)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (28)
BioAssays with compounds reported as biologically active

Experiment Type

Primary Screening (13)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose

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Other (21)
BioAssays deposited by other experimentalists

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BioAssays for PubChem Compound (Select 356285) (28)
PubChem BioAssay
Taxonomy Links for GEO Profiles (Select 104004553) (1)
Taxonomy
OMIM Links for Nucleotide (Select 1889516182) (5)
OMIM
Homo sapiens cellular communication network factor 3 (CCN3), mRNA
Homo sapiens cellular communication network factor 3 (CCN3), mRNA
gi|1519242329|ref|NM_002514.4|

Nucleotide
zinc-regulated GTPase metalloprotein activator 1E isoform X7 [Homo sapiens]
zinc-regulated GTPase metalloprotein activator 1E isoform X7 [Homo sapiens]
gi|1370514033|ref|XP_024303221.1|

Protein

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