BioAssays for PubChem Compound (Select 222492) - PubChem BioAssay - NCBI

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Items: 20

Select item 19189691.

Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress

Source:: ICCB-Longwood Screening Facility, Harvard Medical School

Assay data:281 Active, 189401 Tested

AID:: 1918969

Summary Compounds, Active

Select item 15086022.

Cell-based high throughput primary assay to identify activators of GPR151

Source:: The Scripps Research Institute Molecular Screening Center

Protein Target:: G-protein coupled receptor 151; G-protein coupled receptor PGR7; GPCR-2037; Galanin receptor 4; Galanin-receptor-like protein; GalRL

Assay data:6756 Active, 646675 Tested

AID:: 1508602

Summary Compounds, Active Related BioAssays by Depositor Related BioAssays by Target

Select item 12594223.

Luminescence cell-based high throughput primary assay to identify inhibitors of TEAD-YAP interaction.

Source:: The Scripps Research Institute Molecular Screening Center

Protein Target:: transcriptional coactivator YAP1 isoform 1

Assay data:9273 Active, 641570 Tested

AID:: 1259422

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 12593744.

AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of microphthalmia-associated transcription factor (MITF)

Source:: The Scripps Research Institute Molecular Screening Center

Protein Target:: microphthalmia-associated transcription factor isoform 9

Assay data:5861 Active, 646275 Tested

AID:: 1259374

Summary Compounds, Active PubMed Citation Related BioAssays by Depositor Related BioAssays by Target

Select item 12593105.

AlphaScreen-based biochemical high throughput primary assay to identify activators of the E3 ligase (FBW7).

Source:: The Scripps Research Institute Molecular Screening Center

Assay data:853 Active, 645212 Tested

AID:: 1259310

Summary Compounds, Active PubMed Citation

Select item 12249056.

High-throughput screen for inhibitors of the GIV GBA-motif interaction with Galpha-i G protein subunits

Source:: ICCB-Longwood Screening Facility, Harvard Medical School

Protein Targets:: Guanine nucleotide-binding protein G(i) subunit alpha-3; ...
Total:: 2

Assay data:879 Active, 206873 Tested

AID:: 1224905

Summary Compounds, Active Related BioAssays by Depositor Related BioAssays by Target

Select item 7207177.

Chemical Probes of Kaposi's Sarcoma Herpes Virus Latent Infection

Source:: ICCB-Longwood Screening Facility, Harvard Medical School

Assay data:152 Active, 51130 Tested

AID:: 720717

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 6023148.

A screen for compounds that modulate the activity of the Staphylococcus aureus MgrA protein

Source:: ICCB-Longwood Screening Facility, Harvard Medical School

Protein Target:: MarR family regulatory protein

Assay data:107 Active, 83548 Tested

AID:: 602314

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 5047709.

A screen for compounds that inhibit replication of Vibrio cholerae chromosome II

Source:: ICCB-Longwood Screening Facility, Harvard Medical School

Protein Target:: hypothetical protein VC_A0002

Assay data:352 Active, 132739 Tested

AID:: 504770

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 49316210.

A screen for compounds that inhibit processive DNA synthesis of vaccinia virus

Source:: ICCB-Longwood Screening Facility, Harvard Medical School

Protein Target:: DNA polymerase

Assay data:431 Active, 45756 Tested

AID:: 493162

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 49296711.

A screen for compounds that inhibit the CapD enzyme of Bacillus anthracis

Source:: ICCB-Longwood Screening Facility, Harvard Medical School

Protein Target:: gamma-glutamyltranspeptidase (plasmid)

Assay data:320 Active, 139468 Tested

AID:: 492967

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 42212.

HTS for 14-3-3 protein interaction modulators

Source:: Emory University Molecular Libraries Screening Center

Protein Target:: 14-3-3 protein gamma

Assay data:314 Active, 163857 Tested

AID:: 422

Summary Compounds, Active PubMed Citation Related BioAssays by Depositor Related BioAssays by Target

Select item 32813.

NCI In Vivo Anticancer Drug Screen. Data for tumor model P388 Leukemia (intraperitoneal) in B6D2F1 (BDF1) mice

Source:: DTP/NCI

Assay data:1675 Active, 12988 Tested

AID:: 328

Summary Compounds, Active

Select item 24814.

NCI In Vivo Anticancer Drug Screen. Data for tumor model L1210 Leukemia (intraperitoneal) in B6D2F1 (BDF1) mice

Source:: DTP/NCI

Assay data:1655 Active, 58883 Tested

AID:: 248

Summary Compounds, Active

Select item 17515.

NCI Yeast Anticancer Drug Screen. Data for the mlh1 rad18 strain

Source:: DTP/NCI

Assay data:10990 Active, 86130 Tested

AID:: 175

Summary Compounds, Active

Select item 16716.

NCI Yeast Anticancer Drug Screen. Data for the bub3 strain

Source:: DTP/NCI

Assay data:10366 Active, 85477 Tested

AID:: 167

Summary Compounds, Active

Select item 16517.

NCI Yeast Anticancer Drug Screen. Data for the cln2 rad14 strain

Source:: DTP/NCI

Assay data:8776 Active, 85470 Tested

AID:: 165

Summary Compounds, Active

Select item 16118.

NCI Yeast Anticancer Drug Screen. Data for the sgs1 mgt1 strain

Source:: DTP/NCI

Assay data:10341 Active, 85470 Tested

AID:: 161

Summary Compounds, Active

Select item 15719.

NCI Yeast Anticancer Drug Screen. Data for the mec2-1 strain

Source:: DTP/NCI

Assay data:9577 Active, 86152 Tested

AID:: 157

Summary Compounds, Active

Select item 15520.

NCI Yeast Anticancer Drug Screen. Data for the rad50 strain

Source:: DTP/NCI

Assay data:10610 Active, 86152 Tested

AID:: 155

Summary Compounds, Active

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Target

Proteins (10)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (20)
BioAssays with compounds reported as biologically active

Experiment Type

Primary Screening (7)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose

Depositor Category

NIH MLP (1)
BioAssays deposited by the NIH Molecular Libraries Program
Other (11)
BioAssays deposited by other experimentalists

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BioAssays for PubChem Compound (Select 222492) (20)
PubChem BioAssay
Tssr111512 AND (alive[prop]) (0)
Gene
SAMN35982472 (1)
SRA
Tssr37500 AND (alive[prop]) (0)
Gene
Tssr37506 AND (alive[prop]) (0)
Gene

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