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Binding affinity to lysC riboswitch in Bacillus subtilis
Assay data:3 Active, 2 Activity ≤ 1 µM, 5 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Antibacterial activity against Bacillus subtilis 168 1A1 after 24 hrs by CLSI method
Assay data:13 Tested
SummaryPubMed Citation
Binding affinity to lysine riboswitch 179 lysc of Bacillus subtilis 168 M2 harboring adenosine deletion within 95 to 97 sequence in loop E of P2 motif
Assay data:1 Active, 4 Tested
SummaryCompounds, ActivePubMed Citation
Binding affinity to lysine riboswitch 179 lysc of Bacillus subtilis 168 M1 harboring G163A mutation in P4 motif
Binding affinity to Bacillus subtilis 168 1A1 lysine riboswitch 179 lysc
Inhibition of lysine riboswitch 179 lysc in Bacillus subtilis 168 M2 harboring adenosine deletion within 95 to 97 sequence in loop E of P2 motif assessed as reduction of beta-galactosidase activity at 5 mM after 3 hrs by lacZ reporter gene assay
Assay data:4 Tested
Inhibition of lysine riboswitch 179 lysc in Bacillus subtilis 168 M1 harboring G163A mutation in P4 motif assessed as reduction of beta-galactosidase activity at 5 mM after 3 hrs by lacZ reporter gene assay
Antibacterial activity against Bacillus subtilis 168 M2 harboring adenosine deletion within 95 to 97 sequence in loop E of P2 motif after 24 hrs by CLSI method
Antibacterial activity against Bacillus subtilis 168 M1 harboring G163A mutation in P4 motif after 24 hrs by CLSI method
Inhibition of wild-type Bacillus subtilis 168 1A1 lysine riboswitch 179 lysc assessed as reduction of beta-galactosidase activity at 5 mM after 3 hrs by lacZ reporter gene assay
Antibacterial activity against Bacillus subtilis 1A40 at 1 mM after 3 hrs by CLSI method
Assay data:3 Active, 5 Tested
Antibacterial activity against Bacillus subtilis 168 1A1 at 100 uM after 24 hrs by by CLSI method
Assay data:3 Active, 4 Tested
Binding affinity to Bacillus subtilis 168 1A1 lysine riboswitch 179 lysc by in-line probing assay
Assay data:5 Active, 2 Activity ≤ 1 µM, 14 Tested
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