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Biochemical Assay from US Patent US11926614: "1,2,4-triazole derivatives as tankyrase inhibitors"
Assay data:161 Active, 2 Activity ≤ 1 nM, 160 Activity ≤ 1 µM, 161 Tested
SummaryRelated BioAssays by Target
Measurement of A2A or A2B Binding Affinity Using Radioligand Binding from US Patent US20240076297: "ADENOSINE A2A AND A2B RECEPTOR DUAL ANTAGONISTS FOR IMMUNO-ONCOLOGY"
Assay data:28 Active, 3 Activity ≤ 1 nM, 28 Activity ≤ 1 µM, 28 Tested
Measurement of A2A or A2B Binding Affinity Using SPA from US Patent US20240076297: "ADENOSINE A2A AND A2B RECEPTOR DUAL ANTAGONISTS FOR IMMUNO-ONCOLOGY"
Assay data:18 Active, 15 Activity ≤ 1 µM, 18 Tested
CDK2/Cyclin E1 HTRF Enzyme Activity Assay from US Patent US11919904: "Sulfonylamide compounds as CDK2 inhibitors"
Assay data:14 Active, 14 Activity ≤ 1 µM, 14 Tested
Determination of Binding Constants to Menin-MLL from US Patent US11919901: "Inhibitors of the menin-MLL interaction"
Assay data:253 Active, 249 Activity ≤ 1 nM, 253 Activity ≤ 1 µM, 253 Tested
In Vitro Test of Activities of Jak1, Jak2, Jak3, Tyk2 Kinases from US Patent US11919896: "[1,2,4]triazolo[1,5-a]pyridine compound as JAK inhibitor and use thereof"
Assay data:14 Active, 1 Activity ≤ 1 µM, 34 Tested
Assay data:34 Active, 22 Activity ≤ 1 µM, 34 Tested
AlphaScreen Assay from US Patent US11919855: "Substituted pyrrolidones and piperidones as small molecule inhibitors of EZH2 and EED protein binding"
Assay data:30 Active, 9 Activity ≤ 1 µM, 103 Tested
NAMPT Enzyme Activating Effect (In Vitro Cell-Free Enzyme Assay from US Patent US11918568: "Fused ring compound having urea structure"
Assay data:55 Active, 55 Activity ≤ 1 µM, 55 Tested
NMN Fluorescence Biochemical Assay from US Patent US20240067631: "PYRAZOLE DERIVATIVES USEFUL AS NAMPT MODULATORS"
Assay data:89 Active, 28 Activity ≤ 1 µM, 145 Tested
SARS-CoV-2 3C-like (3CL) protease fluorescence assay (FRET) from US Patent US11912714: "Spiropyrrolidine derived antiviral agents"
Assay data:47 Active, 48 Activity ≤ 1 µM, 48 Tested
Luciferase assay from US Patent US11912681: "Crystalline and salt forms of PPAR agonist compounds"
Assay data:2 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested
Mobility-Shift Assay from US Patent US11912663: "Multi-targeted tyrosine kinase inhibitors and their pharmaceutical uses"
Assay data:14 Active, 15 Activity ≤ 1 µM, 15 Tested
Evaluation of Kd Values from US Patent US20240059728: "NOVEL GALACTOSIDE INHIBITOR OF GALECTINS"
Assay data:6 Active, 3 Activity ≤ 1 nM, 6 Activity ≤ 1 µM, 6 Tested
Coupled Nucleotide Exchange Assay from US Patent US20240059703: "HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE"
Assay data:506 Active, 473 Activity ≤ 1 µM, 513 Tested
TBD from US Patent US20240059694: "COMPOUND CONTAINING 1,3-BENZODIOXOL STRUCTURE AND PREPARATION METHOD AND USE THEREOF"
Assay data:28 Active, 30 Activity ≤ 1 µM, 30 Tested
Assay data:30 Active, 30 Activity ≤ 1 µM, 30 Tested
Determination of Related Protease Inhibition from US Patent US20240059691: "ENZYME INHIBITORS"
Assay data:279 Active, 16 Activity ≤ 1 nM, 253 Activity ≤ 1 µM, 299 Tested
THR/RXR Heterodimer Assay for Thyroid Hormone Receptor Agonist Screening from US Patent US20240059682: "THYROID HORMONE RECEPTOR BETA AGONIST COMPOUNDS"
Assay data:26 Active, 25 Activity ≤ 1 µM, 26 Tested
Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) Assay for Thyroid Hormone Receptor Agonist Screening from US Patent US20240059682: "THYROID HORMONE RECEPTOR BETA AGONIST COMPOUNDS"
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
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