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Human SHP (0B. DAX-like receptors)
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Effect on SHP(NR0B2) dependent reporter activity in HEK293 cells at 20 uM
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Binding affinity to GST-tagged human recombinant SHP at 200 uM by NMR spectroscopy
Assay data:1 Tested
Binding affinity to GST-tagged human recombinant SHP at 100 uM by NMR spectroscopy
Assay data:2 Active, 2 Tested
Late stage assay provider results from the probe development effort to identify inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Displacement of [5,5'-3H2]AHPN from human recombinant GST-SHP at 50 uM by liquid scintillation counting relative to 3-Cl-AHPC
Assay data:8 Tested
Displacement of [5,5'-3H2]AHPN from human recombinant GST-SHP by liquid scintillation counting relative to 3-Cl-AHPC
Assay data:4 Active, 2 Activity ≤ 1 µM, 4 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Displacement of [5,5'-3H2]AHPN from recombinant human GST-SHP partner nuclear orphan receptor at 50 uM
Assay data:7 Tested
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors.
Assay data:14 Active, 14 Tested
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