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Inhibition Assay from Article 10.1074/jbc.M113.521955: "Transition state analogues of Plasmodium falciparum and human orotate phosphoribosyltransferases."
Assay data:20 Active, 19 Activity ≤ 1 µM, 20 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Enzyme Inhibition Assay from Article 10.1021/jm801224t: "Structure-activity relationships of orotidine-5'-monophosphate decarboxylase inhibitors as anticancer agents."
Assay data:4 Active, 4 Activity ≤ 1 µM, 8 Tested
Inhibition of human ODCase
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB
Assay data:3598 Active, 421 Activity ≤ 1 nM, 2233 Activity ≤ 1 µM, 3598 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Inhibition of human ODCase by isothermal titration calorimetry
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of human 5'-monophosphate decarboxylase by VP-ITC microcalorimeter
Reversible inhibition of human uridine 5'-monophosphate synthase at 0.1 to 1 mM after overnight incubation at room temperature by UV spectroscopy
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of human uridine 5'-monophosphate synthase after overnight incubation at room temperature by UV spectroscopy
Irreversible inhibition of human ODCase
Assay data:1 Active, 2 Tested
Reversible inhibition of human ODCase
Assay data:1 Active, 1 Activity ≤ 1 µM, 7 Tested
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