Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19630431.

Safety47 Scan (DiscoverX - Eurofins)

Source:: ChEMBL

Protein Target:: Histamine H2 receptor

Assay data:1 Tested

AID:: 1963043

Summary Related BioAssays by Target

Select item 19630422.

Safety47 Scan (DiscoverX - Eurofins)

Source:: ChEMBL

Protein Target:: Histamine H2 receptor

Assay data:1 Tested

AID:: 1963042

Summary Related BioAssays by Target

Select item 19625363.

Histamine H2 Eurofins Panlabs panel

Source:: ChEMBL

Protein Target:: Histamine H2 receptor

Assay data:1 Tested

AID:: 1962536

Summary Related BioAssays by Target

Select item 19623834.

H2/APT/HS Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: Histamine H2 receptor

Assay data:1 Tested

AID:: 1962383

Summary Related BioAssays by Target

Select item 19623345.

H2/APT/HS Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: Histamine H2 receptor

Assay data:1 Tested

AID:: 1962334

Summary Related BioAssays by Target

Select item 19622356.

H2/APT/HS Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: Histamine H2 receptor

Assay data:1 Tested

AID:: 1962235

Summary Related BioAssays by Target

Select item 19621897.

H2/APT/HS Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: Histamine H2 receptor

Assay data:1 Tested

AID:: 1962189

Summary Related BioAssays by Target

Select item 19621598.

H2/APT/HS Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: Histamine H2 receptor

Assay data:1 Tested

AID:: 1962159

Summary Related BioAssays by Target

Select item 19620939.

H2/APT/HS Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: Histamine H2 receptor

Assay data:1 Tested

AID:: 1962093

Summary Related BioAssays by Target

Select item 196204910.

H2/APT/HS Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: Histamine H2 receptor

Assay data:1 Tested

AID:: 1962049

Summary Related BioAssays by Target

Select item 196176811.

Binding affinity towards human HRH2 in an in vitro assay with cellular components measured by membrane filtration

Source:: ChEMBL

Protein Target:: Histamine H2 receptor

Assay data:61 Active, 32 Activity ≤ 1 µM, 283 Tested

AID:: 1961768

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 196176712.

Agonist activity at human HRH2 in an in vitro cell-based assay measured by time-resolved fluorescence resonance energy transfer method

Source:: ChEMBL

Protein Target:: Histamine H2 receptor

Assay data:12 Active, 7 Activity ≤ 1 µM, 1115 Tested

AID:: 1961767

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 195994113.

Inhibition of histamine h2 (unknown origin)

Source:: ChEMBL

Protein Target:: Histamine H2 receptor

Assay data:2 Tested

AID:: 1959941

Summary PubMed Citation Related BioAssays by Target

Select item 195910014.

Displacement of [3H]tiotidine from recombinant human histamine H2 receptor expressed in CHO-K1 cell membrane at 1 uM incubated for 45 mins by Scintillation counter analysis relative to control

Source:: ChEMBL

Protein Target:: Histamine H2 receptor

Assay data:1 Tested

AID:: 1959100

Summary PubMed Citation Related BioAssays by Target

Select item 195840115.

Displacement of [125I]APT from human recombinant histamine H2 receptor at 10 uM after 120 mins by scintillation counting analysis relative to control

Source:: ChEMBL

Protein Target:: Histamine H2 receptor

Assay data:3 Tested

AID:: 1958401

Summary PubMed Citation Related BioAssays by Target

Select item 195749716.

Antagonist potency at recombinant human histamine H2 receptor expressed in HEK293 cells assessed as inhibition of histamine-induced cAMP accumulation

Source:: ChEMBL

Protein Target:: Histamine H2 receptor

Assay data:1 Active, 1 Tested

AID:: 1957497

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 193328617.

Antagonist activity at histamine H2 receptor (unknown origin) assessed as inhibition constant

Source:: ChEMBL

Protein Target:: Histamine H2 receptor

Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested

AID:: 1933286

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 192575618.

Inhibition of histamine H2 receptor (unknown origin) at 10 uM

Source:: ChEMBL

Protein Target:: Histamine H2 receptor

Assay data:1 Tested

AID:: 1925756

Summary PubMed Citation Related BioAssays by Target

Select item 191516519.

Selectivity interaction (GPCR panel (PDSP screen)) EUB0000307b HRH2

Source:: ChEMBL

Protein Target:: Histamine H2 receptor

Assay data:1 Active, 1 Tested

AID:: 1915165

Summary Compounds, Active Related BioAssays by Target

Select item 191508120.

Selectivity interaction (PRESTO-Tango GPCR-ome screening) EUB0000539a HRH2

Source:: ChEMBL

Protein Target:: Histamine H2 receptor

Assay data:1 Active, 1 Tested

AID:: 1915081

Summary Compounds, Active Related BioAssays by Target

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Target

Proteins (24)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (217)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (10)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (150)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (262)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (5)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose

Assay Project (19)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (683)
BioAssays extracted from the literature
NIH MLP (22)
BioAssays deposited by the NIH Molecular Libraries Program
Other (57)
BioAssays deposited by other experimentalists

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Related BioAssays, by Target Similarity (List) for PubChem BioAss... (762)
Related BioAssays, by Target Similarity (List) for PubChem BioAssay (Select 1962235)
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PubChem BioAssay
ASAH2 N-acylsphingosine amidohydrolase 2 [Homo sapiens]
ASAH2 N-acylsphingosine amidohydrolase 2 [Homo sapiens]
Gene ID:56624

Gene
Gene Links for GEO Profiles (Select 101487188) (1)
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