Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Inhibition of Cytochrome P450 Oxidase from US Patent US20240158438: "POLYPEPTIDE COMPOUND AND APPLICATION THEREOF"
Assay data:2 Active, 31 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Target
CYP Enzyme Inhibition Assay from US Patent US11981669: "1,7-naphthyridine derivative and preparation method and use therefor"
Assay data:8 Tested
SummaryRelated BioAssays by DepositorRelated BioAssays by Target
CYP Enzyme Inhibitory Activity IC50 Assay from US Patent US20240124479: "PYRIMIDINE CARBOXAMIDE COMPOUND AND USE THEREOF"
Assay data:1 Tested
Enzymatic Activity of CYP2C9, CYP2D6, and CYP3A4 from US Patent US20240124454: "TRICYCLIC COMPOUND AND USE THEREOF"
Assay data:10 Tested
CYP inhibitio from US Patent US20240124434: "ATF6 INHIBITORS AND USES THEREOF"
Assay data:10 Active, 3 Activity ≤ 1 µM, 17 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Inhibitory Activity Assay from US Patent US11952364: "TRK inhibitors useful as anticancer drugs"
Assay data:3 Active, 1 Activity ≤ 1 µM, 3 Tested
Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate at 10 uM preincubated for 10 mins followed by NADPH addition and measured after 15 mins by LC-MS/MS analysis
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of CYP2D6 (unknown origin)
Assay data:3 Tested
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Time-dependent inhibition of CYP2D6 (unknown origin)
Inhibition of CYP2D6 in human liver microsomes incubated for 10 mins in presence of NADPH by LC/MS/MS analysis
Assay data:2 Tested
Reversible inhibition of CYP2D6 in human liver microsomes assessed as residual activity at 5 uM using dextromethorphan as substrate preincubated for 30 mins followed by substrate addition measured after 20 mins by LC-MS/MS analysis relative to control
Inhibition of human CYP2D6
Inhibition of CYP2D6 in human liver microsomes
Inhibition of CYP2D6 in human liver microsomes using midazolam as substrate preincubated for 15 mins followed by NADPH addition and measured after 8 mins by LC/MS/MS analysis
Inhibition of CYP2D6 in human liver microsomes using bufuralol as substrate assessed as reduction in substrate hydroxylation incubated for 5 mins in presence of beta-NADPH measured by LC-MS/MS analysis
Assay data:1 Active, 2 Tested
Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate in presence of NADPH by LC-MS/MS analysis
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on