Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19586871.

new record, indexing in progress

AID:: 1958687

Select item 19583022.

new record, indexing in progress

AID:: 1958302

Select item 19518093.

new record, indexing in progress

AID:: 1951809

Select item 19492184.

new record, indexing in progress

AID:: 1949218

Select item 19491495.

new record, indexing in progress

AID:: 1949149

Select item 19384656.

new record, indexing in progress

AID:: 1938465

Select item 19378697.

new record, indexing in progress

AID:: 1937869

Select item 19331278.

new record, indexing in progress

AID:: 1933127

Select item 19292619.

new record, indexing in progress

AID:: 1929261

Select item 192382410.

new record, indexing in progress

AID:: 1923824

Select item 192018111.

In Vitro Activity Against CBP from US Patent US20240016795: "BROMODOMAIN INHIBITORS FOR ANDROGEN RECEPTOR-DRIVEN CANCERS"

Source:: BindingDB

Protein Targets:: CREB-binding protein; ...
Total:: 2

Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested

AID:: 1920181

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191850612.

Inhibition of CBP/p300 in human COLO 320HSR cells assessed as decrease in H3K9 acetylation at 0.3 to 1000 nM measured by western blot analysis

Source:: ChEMBL

Protein Targets:: CREB-binding protein; ...
Total:: 2

Assay data:1 Tested

AID:: 1918506

Summary PubMed Citation Related BioAssays by Target

Select item 191850513.

Inhibition of CBP/p300 in human COLO 320HSR cells assessed as decrease in H3K27 acetylation at 0.3 to 1000 nM measured by western blot analysis

Source:: ChEMBL

Protein Targets:: CREB-binding protein; ...
Total:: 2

Assay data:1 Active, 1 Tested

AID:: 1918505

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 191850414.

Inhibition of CBP/p300 in human COLO 320HSR cells assessed as decrease in H3K18 acetylation at 0.3 to 1000 nM measured by western blot analysis

Source:: ChEMBL

Protein Targets:: CREB-binding protein; ...
Total:: 2

Assay data:1 Active, 1 Tested

AID:: 1918504

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 191849815.

Inhibition of CBP (unknown origin) using Histone H3 substrate at 1 uM relative to control

Source:: ChEMBL

Protein Target:: CREB-binding protein

Assay data:1 Tested

AID:: 1918498

Summary PubMed Citation Related BioAssays by Target

Select item 191847416.

Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assay

Source:: ChEMBL

Protein Targets:: CREB-binding protein; ...
Total:: 2

Assay data:25 Active, 16 Activity ≤ 1 µM, 27 Tested

AID:: 1918474

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 191483717.

Selectivity interaction (BROMOscan? panel (DiscoverX)) EUB0000247b CREBBP

Source:: ChEMBL

Protein Target:: CREB-binding protein

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1914837

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191475918.

Selectivity interaction (BROMOscan (DiscoverX)) EUB0000191c CREBBP

Source:: ChEMBL

Protein Target:: CREB-binding protein

Assay data:1 Tested

AID:: 1914759

Summary Related BioAssays by Target

Select item 191474419.

Selectivity interaction (Bromodomain panel (DSF assay)) EUB0000330a CREBBP

Source:: ChEMBL

Protein Target:: CREB-binding protein

Assay data:1 Tested

AID:: 1914744

Summary Related BioAssays by Target

Select item 191473720.

Selectivity interaction (Bromoscan (DiscoverX, BromoKdELECT)) EUB0000004c CREBBP

Source:: ChEMBL

Protein Target:: CREB-binding protein

Assay data:1 Tested

AID:: 1914737

Summary Related BioAssays by Target

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Target

Proteins (5)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (241)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (9)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (133)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (212)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

Depositor Category

Literature Extraction (363)
BioAssays extracted from the literature
NIH MLP (4)
BioAssays deposited by the NIH Molecular Libraries Program
Other (31)
BioAssays deposited by other experimentalists

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