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Inhibition of FOXO-1 in human HepG2 cells incubated for 20 hrs by Renilla luciferase reporter gene assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of PAX3-FOXO1 driven transcriptional activity in human Rh4 cells assessed as upregulation of BCL2L1 gene expression at 20 uM incubated for 6 hrs by GSEA analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of PAX3-FOXO1 driven transcriptional activity in human Rh4 cells assessed as upregulation of ID1 gene expression at 20 uM incubated for 6 hrs by GSEA analysis
Inhibition of PAX3-FOXO1 driven transcriptional activity in human Rh4 cells assessed as upregulation of VEGFA gene expression at 20 uM incubated for 6 hrs by GSEA analysis
Inhibition of PAX3-FOXO1 driven transcriptional activity in human Rh4 cells assessed as upregulation of SOX9 gene expression at 20 uM incubated for 6 hrs by GSEA analysis
Inhibition of PAX3-FOXO1 driven transcriptional activity in human Rh4 cells assessed as upregulation of KLF10 gene expression at 20 uM incubated for 6 hrs by GSEA analysis
Inhibition of PAX3-FOXO1 driven transcriptional activity in human Rh4 cells assessed as upregulation of TNFRSF12A gene expression at 20 uM incubated for 6 hrs by GSEA analysis
Inhibition of PAX3-FOXO1 driven transcriptional activity in human Rh4 cells assessed as upregulation of SERPINE1 gene expression at 20 uM incubated for 6 hrs by GSEA analysis
Inhibition of PAX3-FOXO1 driven transcriptional activity in human Rh4 cells assessed as upregulation of LBH gene expression at 20 uM incubated for 6 hrs by GSEA analysis
Inhibition of PAX3-FOXO1 driven transcriptional activity in human Rh4 cells assessed as upregulation of KIT gene expression at 20 uM incubated for 6 hrs by GSEA analysis
Inhibition of PAX3-FOXO1 driven transcriptional activity in human Rh4 cells assessed as upregulation of IL-11 gene expression at 20 uM incubated for 6 hrs by GSEA analysis
Inhibition of PAX3-FOXO1 driven transcriptional activity in human Rh4 cells assessed as upregulation of TIMP3 gene expression at 20 uM incubated for 6 hrs by GSEA analysis
Inhibition of PAX3-FOXO1 driven transcriptional activity in human Rh4 cells assessed as upregulation of EPHA2 gene expression at 20 uM incubated for 6 hrs by GSEA analysis
Inhibition of PAX3-FOXO1 driven transcriptional activity in human Rh4 cells assessed as upregulation of DGKD gene expression at 20 uM incubated for 6 hrs by GSEA analysis
Inhibition of PAX3-FOXO1 driven transcriptional activity in human Rh4 cells assessed as upregulation of GADD45B gene expression at 20 uM incubated for 6 hrs by GSEA analysis
Inhibition of PAX3-FOXO1 driven transcriptional activity in human Rh4 cells transfected with ALK-Luc construct incubated for 24 hrs by luciferase assay
Assay data:8 Tested
SummaryPubMed CitationRelated BioAssays by Target
Activation of FoxO1A in human MDA-MB-453 cells after 72 hrs by immunoblot analysis
Activation of FoxO1A in human BT-20 cells after 72 hrs by immunoblot analysis
Activation of FoxO1A in human MDA-MB-231 cells after 72 hrs by immunoblot analysis
Inhibition of FoxO signaling pathway in human HeLa cells assessed as inhibition of luciferase at 100 uM treated 30 mins before induction
Assay data:4 Tested
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