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Inhibition of TNIK (unknown origin) at 10 uM by biochemical hotspot kinase assay relative to control
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of MINK (unknown origin) at 10 uM by biochemical hotspot kinase assay relative to control
Inhibition of Mink1 (unknown origin) at 1 uM relative to control
Assay data:3 Tested
Inhibition of KCNQ1/MINK (unknown origin) at 10 uM
Inhibition of TNIK (unknown origin) by Ambit kinase assay
Inhibition of TNIK (unknown origin) at 10 uM relative to control
Inhibition of MINK1 (unknown origin) at 25 nM relative to control
Assay data:6 Tested
TNIK Human STE Kinase Enzymatic Radiometric Assay from US Patent US11530199: "Analogs for the treatment of disease"
Assay data:39 Active, 45 Activity ≤ 1 µM, 45 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
TNIK Human STE Kinase Enzymatic Radiometric Assay from US Patent US11530197: "Analogs for the treatment of disease"
Inhibition of TNIK (unknown origin) at 100 nM by KINOMEscan assay relative to control
Inhibition of human MINK1 at 10 uM relative to control by Electrophysiological QPatch assay
Inhibition of TNIK (unknown origin)
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of TNIK (unknown origin) at 0.1 uM relative to control
Inhibition of TNIK signalling pathway in human HCT-116 cells assessed as expression of TNIK level at 5 to 40 uM measured after 48 hrs by Western blot analysis
Inhibition of human recombinant TNIK (1 to 367 residues) using RLGRDKYKTLRQIRQ as substrate in presence of ATP incubated for 40 mins by radiometric based scintillation method
Assay data:34 Active, 25 Activity ≤ 1 µM, 54 Tested
Assay data:3 Active, 2 Activity ≤ 1 µM, 5 Tested
Inhibition of MINK1 (unknown origin) assessed as residual activity at 1 uM by radiometric 33 PanQuinase assay relative to control
Inhibition of human MINK assessed as residual activity at 30 uM relative to control
Inhibition of human recombinant TNIK (1 to 367 residues) using RLGRDKYKTLRQIRQ as substrate incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based radiometric scintillation counting method
Assay data:27 Active, 15 Activity ≤ 1 µM, 39 Tested
Inhibition of MINK1 (unknown origin) at 1.0 uM relative to control
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