Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19608961.

Inhibition of TNIK (unknown origin) at 10 uM by biochemical hotspot kinase assay relative to control

Source:: ChEMBL

Protein Target:: TRAF2 and NCK-interacting protein kinase

Assay data:1 Tested

AID:: 1960896

Summary PubMed Citation Related BioAssays by Target

Select item 19608952.

Inhibition of HGK (unknown origin) at 10 uM by biochemical hotspot kinase assay relative to control

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase kinase 4

Assay data:1 Tested

AID:: 1960895

Summary PubMed Citation Related BioAssays by Target

Select item 19608943.

Inhibition of MINK (unknown origin) at 10 uM by biochemical hotspot kinase assay relative to control

Source:: ChEMBL

Protein Target:: Misshapen-like kinase 1

Assay data:1 Tested

AID:: 1960894

Summary PubMed Citation Related BioAssays by Target

Select item 19583734.

Inhibition of Mink1 (unknown origin) at 1 uM relative to control

Source:: ChEMBL

Protein Target:: Misshapen-like kinase 1

Assay data:3 Tested

AID:: 1958373

Summary PubMed Citation Related BioAssays by Target

Select item 19583715.

Inhibition of MAP4K4 (unknown origin) at 1 uM relative to control

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase kinase 4

Assay data:3 Tested

AID:: 1958371

Summary PubMed Citation Related BioAssays by Target

Select item 19542196.

Inhibition of KCNQ1/MINK (unknown origin) at 10 uM

Source:: ChEMBL

Protein Targets:: Misshapen-like kinase 1; ...
Total:: 2

Assay data:1 Tested

AID:: 1954219

Summary PubMed Citation Related BioAssays by Target

Select item 19490747.

Inhibition of TNIK (unknown origin) by Ambit kinase assay

Source:: ChEMBL

Protein Target:: TRAF2 and NCK-interacting protein kinase

Assay data:1 Tested

AID:: 1949074

Summary PubMed Citation Related BioAssays by Target

Select item 19343388.

Inhibition of TNIK (unknown origin) at 10 uM relative to control

Source:: ChEMBL

Protein Target:: TRAF2 and NCK-interacting protein kinase

Assay data:1 Tested

AID:: 1934338

Summary PubMed Citation Related BioAssays by Target

Select item 19282849.

Inhibition of MINK1 (unknown origin) at 25 nM relative to control

Source:: ChEMBL

Protein Target:: Misshapen-like kinase 1

Assay data:6 Tested

AID:: 1928284

Summary PubMed Citation Related BioAssays by Target

Select item 191990910.

MAP4K4 Kinase Activity Assay from US Patent US11795169: "MAP4K4 inhibitors"

Source:: BindingDB

Protein Targets:: Mitogen-activated protein kinase kinase kinase kinase 4; ...
Total:: 1

Assay data:82 Active, 97 Activity ≤ 1 µM, 97 Tested

AID:: 1919909

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191967611.

In Vitro Assay from US Patent US11739078: "Methods of inhibiting kinases"

Source:: BindingDB

Protein Targets:: Mitogen-activated protein kinase kinase kinase kinase 4; ...
Total:: 1

Assay data:100 Active, 110 Activity ≤ 1 µM, 123 Tested

AID:: 1919676

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor Related BioAssays by Target

Select item 191911712.

MAP4K4 Human STE Kinase Enzymatic Radiometric Assay from US Patent US11530199: "Analogs for the treatment of disease"

Source:: BindingDB

Protein Targets:: Mitogen-activated protein kinase kinase kinase kinase 4; ...
Total:: 1

Assay data:23 Active, 43 Activity ≤ 1 µM, 43 Tested

AID:: 1919117

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor Related BioAssays by Target

Select item 191911613.

TNIK Human STE Kinase Enzymatic Radiometric Assay from US Patent US11530199: "Analogs for the treatment of disease"

Source:: BindingDB

Protein Targets:: TRAF2 and NCK-interacting protein kinase; ...
Total:: 1

Assay data:39 Active, 45 Activity ≤ 1 µM, 45 Tested

AID:: 1919116

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor Related BioAssays by Target

Select item 191910914.

MAP4K4 Human STE Kinase Enzymatic Radiometric Assay from US Patent US11530197: "Analogs for the treatment of disease"

Source:: BindingDB

Protein Targets:: Mitogen-activated protein kinase kinase kinase kinase 4; ...
Total:: 1

Assay data:23 Active, 43 Activity ≤ 1 µM, 43 Tested

AID:: 1919109

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor Related BioAssays by Target

Select item 191910815.

TNIK Human STE Kinase Enzymatic Radiometric Assay from US Patent US11530197: "Analogs for the treatment of disease"

Source:: BindingDB

Protein Targets:: TRAF2 and NCK-interacting protein kinase; ...
Total:: 1

Assay data:39 Active, 45 Activity ≤ 1 µM, 45 Tested

AID:: 1919108

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor Related BioAssays by Target

Select item 191468316.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000753a MAP4K4

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase kinase 4

Assay data:1 Tested

AID:: 1914683

Summary Related BioAssays by Target

Select item 191050817.

Inhibition of TNIK (unknown origin) at 100 nM by KINOMEscan assay relative to control

Source:: ChEMBL

Protein Target:: TRAF2 and NCK-interacting protein kinase

Assay data:1 Tested

AID:: 1910508

Summary PubMed Citation Related BioAssays by Target

Select item 190760918.

Inhibition of human MINK1 at 10 uM relative to control by Electrophysiological QPatch assay

Source:: ChEMBL

Protein Target:: Misshapen-like kinase 1

Assay data:1 Tested

AID:: 1907609

Summary PubMed Citation Related BioAssays by Target

Select item 190468619.

Inhibition of TNIK (unknown origin)

Source:: ChEMBL

Protein Target:: TRAF2 and NCK-interacting protein kinase

Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 1904686

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 190059020.

Inhibition of TNIK (unknown origin) at 0.1 uM relative to control

Source:: ChEMBL

Protein Target:: TRAF2 and NCK-interacting protein kinase

Assay data:1 Tested

AID:: 1900590

Summary PubMed Citation Related BioAssays by Target

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Target

Proteins (5)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (143)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (17)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (115)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (149)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

Depositor Category

Literature Extraction (532)
BioAssays extracted from the literature
NIH MLP (1)
BioAssays deposited by the NIH Molecular Libraries Program
Other (72)
BioAssays deposited by other experimentalists

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