Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19635401.

ABL1 Biochemical Kinase Assay from US Patent US20240101536: "COMPOUNDS FOR TREATING CERTAIN LEUKEMIAS"

Source:: BindingDB

Protein Targets:: Tyrosine-protein kinase ABL1; ...
Total:: 1

Assay data:217 Active, 190 Activity ≤ 1 nM, 217 Activity ≤ 1 µM, 217 Tested

AID:: 1963540

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19633172.

Source:: National Center for Advancing Translational Sciences (NCATS)

Deposit Date:: 2024/05/07
Modify Date:: 2024/05/13
Hold-until Date:: 2025/05/03

AID:: 1963317

Select item 19633163.

Source:: National Center for Advancing Translational Sciences (NCATS)

Deposit Date:: 2024/05/07
Modify Date:: 2024/05/13
Hold-until Date:: 2025/05/03

AID:: 1963316

Select item 19633154.

Source:: National Center for Advancing Translational Sciences (NCATS)

Deposit Date:: 2024/05/07
Modify Date:: 2024/05/13
Hold-until Date:: 2025/05/06

AID:: 1963315

Select item 19628855.

ABL1 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase ABL1

Assay data:1 Tested

AID:: 1962885

Summary Related BioAssays by Target

Select item 19627816.

ABL1 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase ABL1

Assay data:1 Tested

AID:: 1962781

Summary Related BioAssays by Target

Select item 19626787.

ABL1 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase ABL1

Assay data:1 Tested

AID:: 1962678

Summary Related BioAssays by Target

Select item 19625798.

ABL1 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase ABL1

Assay data:1 Tested

AID:: 1962579

Summary Related BioAssays by Target

Select item 19624009.

ABL1 Invitrogen Lab (UK) kinase screen (BI)

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase ABL1

Assay data:1 Tested

AID:: 1962400

Summary Related BioAssays by Target

Select item 196225310.

ABL1 Invitrogen Lab (UK) kinase screen (BI)

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase ABL1

Assay data:1 Tested

AID:: 1962253

Summary Related BioAssays by Target

Select item 196086511.

Inhibition of ABL1 (unknown origin) at 10 uM by biochemical hotspot kinase assay

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase ABL1

Assay data:1 Tested

AID:: 1960865

Summary PubMed Citation Related BioAssays by Target

Select item 196051812.

Inhibition of KIT (unknown origin) preincubated for 60 mins followed by ATP addition and measured after 1 hr by ADP-Glo assay

Source:: ChEMBL

Protein Target:: Mast/stem cell growth factor receptor Kit

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1960518

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 196051113.

Inhibition of KIT (unknown origin) assessed as residual activity at 1 uM preincubated for 60 mins followed by ATP addition and measured after 1 hr by ADP-Glo assay relative to control

Source:: ChEMBL

Protein Target:: Mast/stem cell growth factor receptor Kit

Assay data:1 Tested

AID:: 1960511

Summary PubMed Citation Related BioAssays by Target

Select item 195884014.

Binding affinity to Abl-T315I mutant (unknown origin) assessed as inhibition constant

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase ABL1

Assay data:22 Active, 20 Activity ≤ 1 µM, 23 Tested

AID:: 1958840

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 195883915.

Binding affinity to Abl (unknown origin) assessed as inhibition constant

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase ABL1

Assay data:25 Active, 5 Activity ≤ 1 nM, 25 Activity ≤ 1 µM, 25 Tested

AID:: 1958839

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 195835416.

Inhibition of Abl (unknown origin) at 1 uM relative to control

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase ABL1

Assay data:3 Tested

AID:: 1958354

Summary PubMed Citation Related BioAssays by Target

Select item 195646317.

Inhibition of His-tagged human recombinant ABL1 expressed in insect cells at 200 nM by Z'-lyte assay

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase ABL1

Assay data:1 Tested

AID:: 1956463

Summary PubMed Citation Related BioAssays by Target

Select item 195594618.

Inhibition of KIT (unknown origin) at 1 uM relative to control

Source:: ChEMBL

Protein Target:: Mast/stem cell growth factor receptor Kit

Assay data:1 Tested

AID:: 1955946

Summary PubMed Citation Related BioAssays by Target

Select item 195592919.

Inhibition of ABL (unknown origin) at 1 uM relative to control

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase ABL1

Assay data:1 Tested

AID:: 1955929

Summary PubMed Citation Related BioAssays by Target

Select item 195591520.

Inhibition of ABL2 (unknown origin) at 1 uM relative to control

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase ABL2

Assay data:1 Tested

AID:: 1955915

Summary PubMed Citation Related BioAssays by Target

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Target

Proteins (16)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (1,698)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (242)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (1,242)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (1,635)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (2)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
On Hold (3)
On hold BioAssays

Assay Project (9)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (4,091)
BioAssays extracted from the literature
NIH MLP (13)
BioAssays deposited by the NIH Molecular Libraries Program
Other (1,270)
BioAssays deposited by other experimentalists

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PubChem BioAssay
Homo sapiens mRNA; cDNA DKFZp686A02165 (from clone DKFZp686A02165)
Homo sapiens mRNA; cDNA DKFZp686A02165 (from clone DKFZp686A02165)
gi|31874803|emb|BX538317.1|

Nucleotide

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