Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19633821.

Assay for Inhibition of MMP from US Patent US20240050571: "CARBORANE HYDROXAMIC ACID MATRIX METALLOPROTEINASE INHIBITORS AND AGENTS FOR BORON NEUTRON CAPTURE THERAPY"

Source:: BindingDB

Protein Targets:: 72 kDa type IV collagenase; ...
Total:: 3

Assay data:4 Active, 1 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 4 Tested

AID:: 1963382

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19557292.

Inhibition of MMP-9 (unknown origin) using QXL520-gamma-Abu-Pro-Cha-Abu-Smc-His-Ala-Dab(5-FAM)-Ala-Lys-NH2 as fluorogenic substrate at 100 uM preincubated for 10 mins followed by substrate addition and measured for 25 mins by microplate reader assay

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-9

Assay data:1 Tested

AID:: 1955729

Summary PubMed Citation Related BioAssays by Target

Select item 19557273.

Inhibition of MMP-9 (unknown origin) using QXL520-gamma-Abu-Pro-Cha-Abu-Smc-His-Ala-Dab(5-FAM)-Ala-Lys-NH2 as fluorogenic substrate at 1 to 100 uM preincubated for 10 mins followed by substrate addition and measured for 25 mins by microplate reader assay

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-9

Assay data:1 Tested

AID:: 1955727

Summary PubMed Citation Related BioAssays by Target

Select item 19557234.

Inhibition of MMP-9 (unknown origin) using QXL520-gamma-Abu-Pro-Cha-Abu-Smc-His-Ala-Dab(5-FAM)-Ala-Lys-NH2 as fluorogenic substrate preincubated for 10 mins followed by substrate addition and measured for 25 mins by microplate reader assay

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-9

Assay data:1 Tested

AID:: 1955723

Summary PubMed Citation Related BioAssays by Target

Select item 19457555.

Inhibition of MMP-9 (unknown origin) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins followed by substrate addition by fluorometric assay

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-9

Assay data:4 Tested

AID:: 1945755

Summary PubMed Citation Related BioAssays by Target

Select item 19457546.

Inhibition of MMP-3 (unknown origin) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 30 mins by fluorometric assay

Source:: ChEMBL

Protein Target:: Stromelysin-1

Assay data:4 Tested

AID:: 1945754

Summary PubMed Citation Related BioAssays by Target

Select item 19400747.

Inhibition of MMP-9 (unknown origin)

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-9

Assay data:1 Active, 1 Tested

AID:: 1940074

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 19400738.

Inhibition of MMP-3 (unknown origin)

Source:: ChEMBL

Protein Target:: Stromelysin-1

Assay data:1 Active, 1 Tested

AID:: 1940073

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 19400709.

Inhibition of beta-glucosidase activated MMP-9 (unknown origin) relative to control

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-9

Assay data:1 Tested

AID:: 1940070

Summary PubMed Citation Related BioAssays by Target

Select item 194006310.

Inhibition of human MMP-9 at 100 uM relative to control

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-9

Assay data:1 Tested

AID:: 1940063

Summary PubMed Citation Related BioAssays by Target

Select item 194006211.

Inhibition of human MMP-3 at 100 uM relative to control

Source:: ChEMBL

Protein Target:: Stromelysin-1

Assay data:2 Tested

AID:: 1940062

Summary PubMed Citation Related BioAssays by Target

Select item 194006012.

Inhibition of human MMP-1 at 100 uM relative to control

Source:: ChEMBL

Protein Target:: Interstitial collagenase

Assay data:2 Tested

AID:: 1940060

Summary PubMed Citation Related BioAssays by Target

Select item 194005913.

Inhibition of human MMP-3

Source:: ChEMBL

Protein Target:: Stromelysin-1

Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested

AID:: 1940059

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 194005514.

Inhibition of human MMP-9

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-9

Assay data:5 Tested

AID:: 1940055

Summary PubMed Citation Related BioAssays by Target

Select item 194005315.

Inhibition of human MMP-1

Source:: ChEMBL

Protein Target:: Interstitial collagenase

Assay data:5 Tested

AID:: 1940053

Summary PubMed Citation Related BioAssays by Target

Select item 194005216.

Inhibition of MMP-3 (unknown origin) by Colorimetric assay

Source:: ChEMBL

Protein Target:: Stromelysin-1

Assay data:1 Tested

AID:: 1940052

Summary PubMed Citation Related BioAssays by Target

Select item 194005117.

Inhibition of MMP-3 (unknown origin) by fluorescence based assay

Source:: ChEMBL

Protein Target:: Stromelysin-1

Assay data:1 Tested

AID:: 1940051

Summary PubMed Citation Related BioAssays by Target

Select item 193864018.

Inhibition of MMP10 (unknown origin) using FRET peptide

Source:: ChEMBL

Protein Target:: Stromelysin-2

Assay data:1 Active, 1 Tested

AID:: 1938640

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 193863819.

Inhibition of MMP-10 (unknown origin)

Source:: ChEMBL

Protein Target:: Stromelysin-2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1938638

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 193779520.

Inhibition of MMP9 (unknown origin) assessed as inhibition constant

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-9

Assay data:8 Active, 8 Activity ≤ 1 µM, 9 Tested

AID:: 1937795

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

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Proteins (16)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (1,063)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (186)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (873)
BioAssays with the active concentration of tested reagents less than 1 micromolar

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Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (1,250)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (4)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose

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BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

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Literature Extraction (1,726)
BioAssays extracted from the literature
NIH MLP (9)
BioAssays deposited by the NIH Molecular Libraries Program
Other (38)
BioAssays deposited by other experimentalists

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